iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098755

Ensembl Protein ID

ENSPPYP00000014069.2

UniProt Accession

H2P6T8; H2P6T8_PONAB

Genbank Protein ID

ENSPPYP00000014069

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01204304

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000012599.2	ENSPPYT00000014637.2	ENSPPYP00000014069.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.10e-61	202.9	1121	1173

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy a+n+deL++ kG  + v+  ++ d +W++g  e +g  GlfP+n+v+ 
   Q: 1121 QVIAMYDYAANNEDELSFSKGQLINVM--NKDDPDWWQG--EINGVAGLFPSNYVKM 1173
           6899**********************9..8899******..9*************85 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

VMAQFPTAMN GGPNMWAITS EERTKHDRQF DNLKPSGGYI TGDQARNFFL QSGLPAPVLA 60
EIWALSDLNK DGKMDQQEFS IAMKLIKLKL QGQQLPVVLP PIMKQPPMFS PLISARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCGGCCG CCATGTTGTT GTGGGGCTGA GGCGGCGCCC GCGGAGCCCT GAGCGGCCGT 60
GACAGGCTAC GCAACAGGTT CGCGGGCGGC GGCCTGACGA CCAAGCCGGC TGCAGTGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	91.35	0.00e+00	2093.00
IUUC-Apl-004205	Anas platyrhynchos	77.47	0.00e+00	2377.00
IUUC-Aca-004287	Anolis carolinensis	77.39	0.00e+00	1605.00
IUUC-Ago-007935	Ashbya gossypii	32.03	1.00e-12	68.20
IUUC-Ani-009428	Aspergillus nidulans	43.66	7.00e-11	63.20
IUUC-Ame-011759	Astyanax mexicanus	62.51	0.00e+00	1197.00
IUUC-Bta-013248	Bos taurus	89.15	0.00e+00	2003.00
IUUC-Cel-018490	Caenorhabditis elegans	33.48	2.00e-53	204.00
IUUC-Cfa-020628	Canis familiaris	91.77	0.00e+00	2107.00
IUUC-Cpo-022427	Cavia porcellus	78.56	0.00e+00	2516.00
IUUC-Csa-023122	Chlorocebus sabaeus	92.82	0.00e+00	2152.00
IUUC-Cho-024969	Choloepus hoffmanni	56.11	0.00e+00	1076.00
IUUC-Cin-025435	Ciona intestinalis	42.87	0.00e+00	877.00
IUUC-Csv-026290	Ciona savignyi	51.20	0.00e+00	671.00
IUUC-Cgl-026697	Colletotrichum gloeosporioides	38.60	3.00e-08	54.30
IUUC-Cne-026918	Cryptococcus neoformans	35.53	2.00e-38	155.00
IUUC-Dre-027849	Danio rerio	62.30	0.00e+00	1149.00
IUUC-Dno-029419	Dasypus novemcinctus	91.27	0.00e+00	2098.00
IUUC-Dor-030504	Dipodomys ordii	76.28	0.00e+00	1683.00
IUUC-Dme-032099	Drosophila melanogaster	33.41	9.00e-59	222.00
IUUC-Eca-034196	Equus caballus	91.68	0.00e+00	2052.00
IUUC-Eeu-034972	Erinaceus europaeus	68.44	0.00e+00	639.00
IUUC-Fca-035757	Felis catus	91.19	0.00e+00	2107.00
IUUC-Fal-037531	Ficedula albicollis	83.72	0.00e+00	1689.00
IUUC-Gmo-039632	Gadus morhua	50.39	0.00e+00	1148.00
IUUC-Gga-041012	Gallus gallus	77.58	0.00e+00	1862.00
IUUC-Gac-041948	Gasterosteus aculeatus	58.83	0.00e+00	1186.00
IUUC-Ggo-045405	Gorilla gorilla	92.32	0.00e+00	2702.00
IUUC-Hsa-046833	Homo sapiens	96.90	0.00e+00	2155.00
IUUC-Kpa-049215	Komagataella pastoris	35.46	7.00e-15	75.50
IUUC-Lch-050094	Latimeria chalumnae	72.54	0.00e+00	1629.00
IUUC-Loc-052646	Lepisosteus oculatus	68.58	0.00e+00	1388.00
IUUC-Laf-053798	Loxodonta africana	87.75	0.00e+00	1442.00
IUUC-Mcc-054709	Macaca mulatta	96.25	0.00e+00	2174.00
IUUC-Meu-056396	Macropus eugenii	77.41	0.00e+00	1482.00
IUUC-Mga-059997	Meleagris gallopavo	81.65	0.00e+00	1983.00
IUUC-Mmr-060891	Microcebus murinus	90.78	0.00e+00	2146.00
IUUC-Mmu-064226	Mus musculus	85.32	0.00e+00	2082.00
IUUC-Mpu-066431	Mustela putorius furo	88.66	0.00e+00	2075.00
IUUC-Mlu-068190	Myotis lucifugus	91.44	0.00e+00	2098.00
IUUC-Nle-070116	Nomascus leucogenys	96.37	0.00e+00	1803.00
IUUC-Opr-070815	Ochotona princeps	77.10	0.00e+00	1708.00
IUUC-Ont-072464	Oreochromis niloticus	62.29	0.00e+00	1179.00
IUUC-Ola-086482	Oryzias latipes	58.61	0.00e+00	1169.00
IUUC-Oga-088449	Otolemur garnettii	90.86	0.00e+00	2056.00
IUUC-Oar-090275	Ovis aries	89.56	0.00e+00	2045.00
IUUC-Ptr-091667	Pan troglodytes	96.08	0.00e+00	2131.00
IUUC-Pan-091723	Papio anubis	92.00	0.00e+00	1848.00
IUUC-Psi-093136	Pelodiscus sinensis	80.31	0.00e+00	1898.00
IUUC-Pfo-097486	Poecilia formosa	60.22	0.00e+00	1211.00
IUUC-Pca-101134	Procavia capensis	89.30	0.00e+00	1186.00
IUUC-Pva-102433	Pteropus vampyrus	83.44	0.00e+00	1899.00
IUUC-Rno-105691	Rattus norvegicus	89.72	0.00e+00	2143.00
IUUC-Sce-106410	Saccharomyces cerevisiae	30.43	7.00e-13	68.90
IUUC-Spo-108101	Schizosaccharomyces pombe	42.42	4.00e-15	77.00
IUUC-Sar-112978	Sorex araneus	89.99	0.00e+00	1422.00
IUUC-Sre-115028	Sporisorium reilianum	36.71	2.00e-33	139.00
IUUC-Ssc-115562	Sus scrofa	84.07	0.00e+00	1868.00
IUUC-Tgu-116758	Taeniopygia guttata	81.20	0.00e+00	1963.00
IUUC-Tru-117789	Takifugu rubripes	60.16	0.00e+00	1203.00
IUUC-Tni-119752	Tetraodon nigroviridis	56.49	0.00e+00	1261.00
IUUC-Tbe-127477	Tupaia belangeri	92.25	0.00e+00	759.00
IUUC-Ttr-129196	Tursiops truncatus	88.98	0.00e+00	2001.00
IUUC-Vpa-130035	Vicugna pacos	80.42	0.00e+00	632.00
IUUC-Xtr-132905	Xenopus tropicalis	57.33	0.00e+00	1384.00
IUUC-Xma-133300	Xiphophorus maculatus	61.42	0.00e+00	1153.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence