iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053918

Ensembl Protein ID

ENSLAFP00000008306.3

UniProt Accession

G3T4L2; G3T4L2_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KDM5A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009908.3	ENSLAFT00000009913.3	ENSLAFP00000008306.3
ENSLAFG00000009908.3	ENSLAFT00000025601.1	ENSLAFP00000029461.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-13	51.2	297	344

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vC +Cg+g +++ +l+ C+ C++ +H  Cl ++  +++p+ + w CpkC +
   Q: 297  VCMFCGRGNNED-KLLLCDGCDDSYHTFCLIPP-LPDVPKGD-WRCPKCVA 344
           8*********88.6*******************.*******7.******75 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

ITMAGVGPGG YAAEFVPPPE CPVFEPSWEE FTDPLSFIGR IRPLAEKTGI CKIRPPKDWQ 60
PPFACEVKSF RFTPRVQRLN ELEAMTRVRL DFLDQLAKFW ELQGSTLKIP IVERKILDLY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTACCATGG CGGGTGTGGG GCCAGGAGGC TACGCGGCGG AGTTCGTGCC ACCACCTGAG 60
TGCCCGGTGT TTGAGCCCAG CTGGGAGGAG TTCACTGACC CACTCAGCTT CATCGGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002061	Ailuropoda melanoleuca	91.58	0.00e+00	2571.00
IUUC-Apl-004141	Anas platyrhynchos	85.25	0.00e+00	2419.00
IUUC-Aca-004952	Anolis carolinensis	84.14	0.00e+00	2426.00
IUUC-Ame-011323	Astyanax mexicanus	69.65	0.00e+00	1744.00
IUUC-Bta-012902	Bos taurus	90.67	0.00e+00	2596.00
IUUC-Cja-018988	Callithrix jacchus	90.13	0.00e+00	2388.00
IUUC-Cfa-020212	Canis familiaris	91.26	0.00e+00	2562.00
IUUC-Cpo-022221	Cavia porcellus	87.76	0.00e+00	1664.00
IUUC-Csa-023575	Chlorocebus sabaeus	91.33	0.00e+00	2597.00
IUUC-Cho-024280	Choloepus hoffmanni	90.65	0.00e+00	1587.00
IUUC-Csv-026185	Ciona savignyi	42.55	0.00e+00	923.00
IUUC-Dre-027909	Danio rerio	68.43	0.00e+00	1426.00
IUUC-Dno-029473	Dasypus novemcinctus	90.68	0.00e+00	2456.00
IUUC-Dor-030281	Dipodomys ordii	84.76	0.00e+00	1023.00
IUUC-Ete-033144	Echinops telfairi	92.85	0.00e+00	879.00
IUUC-Eca-034265	Equus caballus	89.87	0.00e+00	2560.00
IUUC-Fca-035476	Felis catus	91.70	0.00e+00	2571.00
IUUC-Fal-037078	Ficedula albicollis	84.46	0.00e+00	2225.00
IUUC-Gga-040466	Gallus gallus	84.76	0.00e+00	2506.00
IUUC-Gac-042566	Gasterosteus aculeatus	69.69	0.00e+00	1871.00
IUUC-Ggo-044524	Gorilla gorilla	83.54	0.00e+00	2116.00
IUUC-Hsa-045821	Homo sapiens	91.21	0.00e+00	2593.00
IUUC-Kpa-049245	Komagataella pastoris	24.79	1.00e-27	119.00
IUUC-Lch-050630	Latimeria chalumnae	71.71	0.00e+00	2005.00
IUUC-Loc-051963	Lepisosteus oculatus	70.44	0.00e+00	1832.00
IUUC-Mcc-055672	Macaca mulatta	91.27	0.00e+00	2589.00
IUUC-Mga-059192	Meleagris gallopavo	77.36	0.00e+00	2118.00
IUUC-Mmr-060968	Microcebus murinus	90.53	0.00e+00	2591.00
IUUC-Mdo-062945	Monodelphis domestica	88.94	0.00e+00	2523.00
IUUC-Mmu-063614	Mus musculus	89.67	0.00e+00	2551.00
IUUC-Mpu-066349	Mustela putorius furo	91.52	0.00e+00	2571.00
IUUC-Mlu-067363	Myotis lucifugus	91.27	0.00e+00	2633.00
IUUC-Nle-070142	Nomascus leucogenys	91.27	0.00e+00	2592.00
IUUC-Opr-071002	Ochotona princeps	81.44	0.00e+00	1195.00
IUUC-Ont-072471	Oreochromis niloticus	71.17	0.00e+00	1642.00
IUUC-Oan-072797	Ornithorhynchus anatinus	76.69	0.00e+00	1882.00
IUUC-Ocu-074164	Oryctolagus cuniculus	89.64	0.00e+00	2620.00
IUUC-Ola-087076	Oryzias latipes	69.54	0.00e+00	1870.00
IUUC-Oga-088350	Otolemur garnettii	88.69	0.00e+00	2484.00
IUUC-Oar-090045	Ovis aries	90.46	0.00e+00	2580.00
IUUC-Ptr-091199	Pan troglodytes	91.63	0.00e+00	2590.00
IUUC-Pan-092094	Papio anubis	86.86	0.00e+00	2500.00
IUUC-Psi-093550	Pelodiscus sinensis	84.87	0.00e+00	2335.00
IUUC-Pfo-097266	Poecilia formosa	71.39	0.00e+00	1657.00
IUUC-Pab-098576	Pongo abelii	91.28	0.00e+00	2591.00
IUUC-Pca-100123	Procavia capensis	84.10	0.00e+00	1378.00
IUUC-Pva-103109	Pteropus vampyrus	84.54	0.00e+00	2410.00
IUUC-Pgr-103434	Puccinia graminis	33.94	1.00e-26	114.00
IUUC-Rno-105664	Rattus norvegicus	89.55	0.00e+00	2541.00
IUUC-Sha-107506	Sarcophilus harrisii	86.51	0.00e+00	2161.00
IUUC-Smo-108843	Selaginella moellendorffii	52.08	9.00e-11	62.40
IUUC-Sar-113052	Sorex araneus	89.87	0.00e+00	2566.00
IUUC-Sbi-114173	Sorghum bicolor	58.14	8.00e-12	64.30
IUUC-Tgu-116613	Taeniopygia guttata	84.34	0.00e+00	2417.00
IUUC-Tru-118604	Takifugu rubripes	69.34	0.00e+00	1911.00
IUUC-Tni-120779	Tetraodon nigroviridis	69.00	0.00e+00	1885.00
IUUC-Ttr-129242	Tursiops truncatus	88.94	0.00e+00	2502.00
IUUC-Vpa-130429	Vicugna pacos	85.95	0.00e+00	1375.00
IUUC-Xtr-131762	Xenopus tropicalis	70.41	0.00e+00	1923.00
IUUC-Xma-133693	Xiphophorus maculatus	69.10	0.00e+00	1917.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence