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Tag Content
iUUCD ID IUUC-Eca-033471
Ensembl Protein ID ENSECAP00000006288.1
UniProt Accession F6T4C6; F6T4C6_HORSE
Protein Name DNA repair protein REV1
Gene Name REV1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSECAG00000007804.1 ENSECAT00000008405.1 ENSECAP00000006288.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBM 7.00e-21 73.3 1014 1042
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBM
   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP+e+Q+E++a+++q++
   Q: 1014 AFSQVDPEVFAALPPELQKELKAAYDQRQ 1042
           59*************************98 PP
   
Organism Equus caballus
Functional Description
(View)

Functional Description


     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
 Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
MRRGGWRRRA ENDGWEKWGG YMAAKVQKLE EQFRSDATMQ KDGTSSTIFS GVAIYVNGYT 60
DPSAEELRKL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 120
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Protein Fasta Sequence


>IUUC-Eca-033471|UBD,UBM|Equus caballus
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Nucleotide Sequence
(Fasta)
ATGAGACGCG GTGGATGGAG AAGGCGTGCT GAAAATGATG GCTGGGAAAA ATGGGTGTGT 60
TTTAAAAGAA TAAAAATAGT TATATTGAAC TGTCTAGGTA TTTTTCATTC TTCTTTTAGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Eca-033471|UBD,UBM|Equus caballus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC
PROSITE

PS50172--BRCT
PS50173--UMUC
Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C
SMART

SM00292--BRCT
Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV
KEGG ecb:100050347
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 30.88 2.00e-33 137.00
IUUC-Aml-001185 Ailuropoda melanoleuca 90.43 0.00e+00 2221.00
IUUC-Atr-002915 Amborella trichopoda 32.54 3.00e-83 303.00
IUUC-Apl-004054 Anas platyrhynchos 75.79 0.00e+00 1821.00
IUUC-Aca-004304 Anolis carolinensis 68.86 0.00e+00 1677.00
IUUC-Aly-005696 Arabidopsis lyrata 34.10 2.00e-84 307.00
IUUC-Ath-006893 Arabidopsis thaliana 33.63 2.00e-84 307.00
IUUC-Ago-007722 Ashbya gossypii 27.95 5.00e-39 156.00
IUUC-Acl-008347 Aspergillus clavatus 37.67 1.00e-87 318.00
IUUC-Afl-008444 Aspergillus flavus 36.57 1.00e-86 315.00
IUUC-Afu-008837 Aspergillus fumigatus 30.73 1.00e-85 311.00
IUUC-Ani-009188 Aspergillus nidulans 38.18 6.00e-92 332.00
IUUC-Ang-009866 Aspergillus niger 39.76 1.00e-96 348.00
IUUC-Aor-010107 Aspergillus oryzae 36.57 1.00e-86 314.00
IUUC-Ate-010359 Aspergillus terreus 33.39 2.00e-91 330.00
IUUC-Ame-010664 Astyanax mexicanus 49.56 0.00e+00 1117.00
IUUC-Bgr-012244 Blumeria graminis 29.01 5.00e-82 299.00
IUUC-Bta-013405 Bos taurus 82.72 0.00e+00 1865.00
IUUC-Bci-013849 Botrytis cinerea 31.36 4.00e-87 316.00
IUUC-Bdi-014066 Brachypodium distachyon 36.76 7.00e-85 308.00
IUUC-Bol-015544 Brassica oleracea 34.98 2.00e-86 313.00
IUUC-Bra-017792 Brassica rapa 34.50 1.00e-82 301.00
IUUC-Cel-018148 Caenorhabditis elegans 35.80 2.00e-82 300.00
IUUC-Cja-019742 Callithrix jacchus 75.96 0.00e+00 1531.00
IUUC-Cfa-020112 Canis familiaris 90.91 0.00e+00 2253.00
IUUC-Cpo-022152 Cavia porcellus 84.13 0.00e+00 2140.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 43.15 2.00e-41 164.00
IUUC-Csa-023504 Chlorocebus sabaeus 87.88 0.00e+00 2194.00
IUUC-Cho-024780 Choloepus hoffmanni 68.10 0.00e+00 745.00
IUUC-Cin-025276 Ciona intestinalis 41.99 4.00e-111 395.00
IUUC-Csv-026283 Ciona savignyi 44.10 1.00e-114 407.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 28.42 1.00e-91 331.00
IUUC-Cne-027079 Cryptococcus neoformans 34.71 6.00e-79 289.00
IUUC-Cme-027346 Cyanidioschyzon merolae 28.15 1.00e-46 181.00
IUUC-Dre-028073 Danio rerio 51.17 0.00e+00 1121.00
IUUC-Dno-030038 Dasypus novemcinctus 83.51 0.00e+00 2058.00
IUUC-Dor-031100 Dipodomys ordii 82.65 0.00e+00 1520.00
IUUC-Dse-031310 Dothistroma septosporum 30.01 1.00e-87 318.00
IUUC-Dme-031991 Drosophila melanogaster 41.21 4.00e-110 392.00
IUUC-Ete-033082 Echinops telfairi 77.53 0.00e+00 1434.00
IUUC-Eeu-034993 Erinaceus europaeus 85.22 0.00e+00 1434.00
IUUC-Fca-035367 Felis catus 89.55 0.00e+00 2144.00
IUUC-Fal-036973 Ficedula albicollis 75.85 0.00e+00 1765.00
IUUC-Fox-037677 Fusarium oxysporum 32.10 1.00e-90 328.00
IUUC-Fso-038252 Fusarium solani 32.59 6.00e-95 342.00
IUUC-Gmo-039669 Gadus morhua 60.33 6.00e-172 598.00
IUUC-Ggr-039988 Gaeumannomyces graminis 33.39 2.00e-86 314.00
IUUC-Gga-040423 Gallus gallus 76.10 0.00e+00 1820.00
IUUC-Gac-042134 Gasterosteus aculeatus 50.77 0.00e+00 804.00
IUUC-Gma-042929 Glycine max 36.40 6.00e-89 322.00
IUUC-Ggo-044528 Gorilla gorilla 88.28 0.00e+00 2191.00
IUUC-Hsa-046259 Homo sapiens 88.04 0.00e+00 2157.00
IUUC-Hvu-047139 Hordeum vulgare 35.87 2.00e-57 216.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 87.32 0.00e+00 2161.00
IUUC-Kpa-049169 Komagataella pastoris 29.12 2.00e-61 230.00
IUUC-Lch-050471 Latimeria chalumnae 65.24 0.00e+00 1566.00
IUUC-Lpe-050800 Leersia perrieri 32.68 4.00e-87 316.00
IUUC-Loc-052320 Lepisosteus oculatus 47.25 0.00e+00 937.00
IUUC-Lma-053149 Leptosphaeria maculans 29.58 3.00e-85 310.00
IUUC-Laf-053810 Loxodonta africana 84.76 0.00e+00 2011.00
IUUC-Mcc-055574 Macaca mulatta 88.20 0.00e+00 2147.00
IUUC-Meu-055945 Macropus eugenii 65.71 0.00e+00 1150.00
IUUC-Mor-057195 Magnaporthe oryzae 28.37 5.00e-102 365.00
IUUC-Mpo-057488 Magnaporthe poae 34.44 2.00e-86 314.00
IUUC-Mtr-057955 Medicago truncatula 35.80 3.00e-90 326.00
IUUC-Mla-059027 Melampsora laricipopulina 36.20 9.00e-80 291.00
IUUC-Mga-060156 Meleagris gallopavo 76.03 0.00e+00 1825.00
IUUC-Mvi-060398 Microbotryum violaceum 35.46 3.00e-80 293.00
IUUC-Mmr-061113 Microcebus murinus 89.95 0.00e+00 2184.00
IUUC-Mdo-063001 Monodelphis domestica 82.55 0.00e+00 1994.00
IUUC-Mmu-063180 Mus musculus 82.15 0.00e+00 2022.00
IUUC-Mac-065551 Musa acuminata 38.11 3.00e-54 206.00
IUUC-Mpu-066525 Mustela putorius furo 90.27 0.00e+00 2209.00
IUUC-Mlu-067877 Myotis lucifugus 87.72 0.00e+00 2142.00
IUUC-Nfi-068418 Neosartorya fischeri 32.92 8.00e-84 305.00
IUUC-Ncr-068648 Neurospora crassa 31.70 3.00e-88 320.00
IUUC-Nle-069959 Nomascus leucogenys 88.28 0.00e+00 2170.00
IUUC-Opr-070522 Ochotona princeps 83.43 0.00e+00 1197.00
IUUC-Ont-072293 Oreochromis niloticus 45.68 0.00e+00 814.00
IUUC-Oan-073519 Ornithorhynchus anatinus 79.29 0.00e+00 1947.00
IUUC-Ocu-074492 Oryctolagus cuniculus 84.02 0.00e+00 1948.00
IUUC-Oba-075567 Oryza barthii 32.94 6.00e-89 322.00
IUUC-Obr-076332 Oryza brachyantha 36.78 1.00e-85 311.00
IUUC-Ogl-077348 Oryza glaberrima 32.94 6.00e-89 322.00
IUUC-Ogu-078779 Oryza glumaepatula 29.25 1.00e-102 367.00
IUUC-Oin-079738 Oryza indica 30.36 1.00e-76 281.00
IUUC-Olo-080701 Oryza longistaminata 30.42 5.00e-77 283.00
IUUC-Ome-081708 Oryza meridionalis 32.92 1.00e-84 308.00
IUUC-Oni-082251 Oryza nivara 32.63 6.00e-86 312.00
IUUC-Opu-083528 Oryza punctata 31.49 2.00e-80 294.00
IUUC-Oru-084293 Oryza rufipogon 32.19 1.00e-83 305.00
IUUC-Osa-085549 Oryza sativa 32.94 1.00e-88 321.00
IUUC-Ola-086793 Oryzias latipes 49.50 0.00e+00 834.00
IUUC-Olu-087786 Ostreococcus lucimarinus 28.36 2.00e-60 227.00
IUUC-Oga-089006 Otolemur garnettii 88.01 0.00e+00 2144.00
IUUC-Oar-089597 Ovis aries 83.35 0.00e+00 2029.00
IUUC-Ptr-091520 Pan troglodytes 88.12 0.00e+00 2159.00
IUUC-Pan-092333 Papio anubis 88.84 0.00e+00 2131.00
IUUC-Psi-094004 Pelodiscus sinensis 78.09 0.00e+00 1899.00
IUUC-Pma-094128 Petromyzon marinus 53.55 2.00e-93 336.00
IUUC-Pno-094849 Phaeosphaeria nodorum 29.33 8.00e-82 298.00
IUUC-Ppa-095714 Physcomitrella patens 31.45 7.00e-92 332.00
IUUC-Pfo-096569 Poecilia formosa 52.64 0.00e+00 807.00
IUUC-Pab-097960 Pongo abelii 87.72 0.00e+00 2152.00
IUUC-Pop-098921 Populus trichocarpa 37.01 1.00e-84 308.00
IUUC-Pca-100509 Procavia capensis 69.65 0.00e+00 1212.00
IUUC-Ppe-101730 Prunus persica 31.71 1.00e-92 334.00
IUUC-Pva-102142 Pteropus vampyrus 87.00 0.00e+00 2116.00
IUUC-Pgr-103446 Puccinia graminis 31.67 2.00e-71 264.00
IUUC-Ptt-103849 Puccinia triticina 30.41 5.00e-74 273.00
IUUC-Pte-104128 Pyrenophora teres 31.09 7.00e-84 305.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 34.81 1.00e-81 298.00
IUUC-Rno-104871 Rattus norvegicus 80.33 0.00e+00 1972.00
IUUC-Sce-106236 Saccharomyces cerevisiae 26.80 9.00e-40 159.00
IUUC-Sha-106962 Sarcophilus harrisii 81.96 0.00e+00 1969.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 31.57 1.00e-63 238.00
IUUC-Spo-108170 Schizosaccharomyces pombe 34.30 3.00e-64 240.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 34.97 3.00e-88 320.00
IUUC-Smo-109554 Selaginella moellendorffii 36.23 2.00e-84 307.00
IUUC-Sit-110479 Setaria italica 36.24 7.00e-71 262.00
IUUC-Sly-111752 Solanum lycopersicum 37.55 2.00e-90 327.00
IUUC-Sar-113304 Sorex araneus 87.19 0.00e+00 2086.00
IUUC-Sbi-114196 Sorghum bicolor 36.69 1.00e-72 268.00
IUUC-Sre-115151 Sporisorium reilianum 30.51 1.00e-85 312.00
IUUC-Ssc-116104 Sus scrofa 87.66 0.00e+00 2142.00
IUUC-Tgu-117438 Taeniopygia guttata 76.03 0.00e+00 1805.00
IUUC-Tru-118553 Takifugu rubripes 47.44 0.00e+00 990.00
IUUC-Tsy-119056 Tarsius syrichta 85.59 0.00e+00 2005.00
IUUC-Tni-119933 Tetraodon nigroviridis 47.57 0.00e+00 954.00
IUUC-Tca-121376 Theobroma cacao 32.23 1.00e-111 397.00
IUUC-Tre-121972 Trichoderma reesei 35.07 2.00e-81 297.00
IUUC-Tvi-122342 Trichoderma virens 35.77 1.00e-81 298.00
IUUC-Tae-123898 Triticum aestivum 33.19 2.00e-90 327.00
IUUC-Tur-126735 Triticum urartu 30.37 7.00e-36 145.00
IUUC-Tme-126999 Tuber melanosporum 32.29 3.00e-80 294.00
IUUC-Tbe-127280 Tupaia belangeri 87.94 5.00e-141 495.00
IUUC-Ttr-129104 Tursiops truncatus 87.43 0.00e+00 2107.00
IUUC-Uma-129562 Ustilago maydis 35.60 5.00e-81 296.00
IUUC-Vda-129862 Verticillium dahliae 31.44 1.00e-90 328.00
IUUC-Vpa-130819 Vicugna pacos 84.79 0.00e+00 1114.00
IUUC-Vvi-131111 Vitis vinifera 34.12 4.00e-84 306.00
IUUC-Xtr-132629 Xenopus tropicalis 61.61 0.00e+00 1414.00
IUUC-Xma-134065 Xiphophorus maculatus 45.69 0.00e+00 806.00
IUUC-Yli-134633 Yarrowia lipolytica 32.63 2.00e-65 244.00
IUUC-Zma-135176 Zea mays 32.45 1.00e-86 315.00
Created Date 25-Jun-2017

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