iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049991

Ensembl Protein ID

ENSLACP00000006462.2

UniProt Accession

H3A9Z1; H3A9Z1_LATCH

Genbank Protein ID

ENSLACP00000006462

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AFYH01047151

Gene Name

LYN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000005733.2	ENSLACT00000006515.2	ENSLACP00000006462.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.20e-17	62.4	69	125

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + + +ly+yea + d+L +kkGd+++v+   e+ ++W+k+ + +++k+G++P+n+v++++
   Q: 69   NIFVALYPYEAMHPDDLGFKKGDKLKVL---EEQGEWWKARSLTTKKEGFIPSNYVARIN 125
           57899***********************...899************************97 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MGCVKSKSFM NSGEDGINKK NQPVRTTEQT IYVRDPTSNN RQMPHSNTDS HLLPGQRFKH 60
LDEEAKGGNI FVALYPYEAM HPDDLGFKKG DKLKVLEEQG EWWKARSLTT KKEGFIPSNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCAAGCTGG TGTGTTTGGT TTTACCCAGG AGAGTTTCTG ATACTTTTAT TTTTTTTAAG 60
TTTTATATTA TTTTTATTGC AGTTGTAAGA AAGATTCGAC GTGAAAGGAG GTTTCTTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0090022--P:regulation of neutrophil chemotaxis
GO:0009611--P:response to wounding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001812	Ailuropoda melanoleuca	82.14	0.00e+00	891.00
IUUC-Apl-004139	Anas platyrhynchos	81.70	0.00e+00	884.00
IUUC-Aca-004333	Anolis carolinensis	80.04	0.00e+00	862.00
IUUC-Ame-011257	Astyanax mexicanus	77.37	0.00e+00	845.00
IUUC-Bta-013257	Bos taurus	81.55	0.00e+00	890.00
IUUC-Cja-018827	Callithrix jacchus	81.36	0.00e+00	885.00
IUUC-Cfa-020816	Canis familiaris	81.94	0.00e+00	890.00
IUUC-Cpo-021423	Cavia porcellus	80.78	0.00e+00	881.00
IUUC-Csa-024244	Chlorocebus sabaeus	81.36	0.00e+00	883.00
IUUC-Dre-028518	Danio rerio	78.65	0.00e+00	846.00
IUUC-Dno-029322	Dasypus novemcinctus	81.75	0.00e+00	887.00
IUUC-Dor-030706	Dipodomys ordii	72.82	0.00e+00	776.00
IUUC-Eca-034193	Equus caballus	82.14	0.00e+00	895.00
IUUC-Fca-035937	Felis catus	68.68	0.00e+00	723.00
IUUC-Fal-037273	Ficedula albicollis	81.94	0.00e+00	890.00
IUUC-Gmo-039677	Gadus morhua	74.78	0.00e+00	739.00
IUUC-Gga-040417	Gallus gallus	80.19	0.00e+00	861.00
IUUC-Gac-042490	Gasterosteus aculeatus	72.15	0.00e+00	797.00
IUUC-Ggo-045096	Gorilla gorilla	81.36	0.00e+00	886.00
IUUC-Hsa-046214	Homo sapiens	81.36	0.00e+00	886.00
IUUC-Itr-048354	Ictidomys tridecemlineatus	82.14	0.00e+00	892.00
IUUC-Loc-052309	Lepisosteus oculatus	80.62	0.00e+00	875.00
IUUC-Laf-053568	Loxodonta africana	81.94	0.00e+00	891.00
IUUC-Mcc-054849	Macaca mulatta	81.36	0.00e+00	883.00
IUUC-Meu-056170	Macropus eugenii	68.74	0.00e+00	707.00
IUUC-Mga-060194	Meleagris gallopavo	71.43	0.00e+00	691.00
IUUC-Mmr-061519	Microcebus murinus	81.55	0.00e+00	886.00
IUUC-Mdo-062090	Monodelphis domestica	73.79	0.00e+00	808.00
IUUC-Mmu-063760	Mus musculus	81.55	0.00e+00	888.00
IUUC-Mpu-065677	Mustela putorius furo	82.14	0.00e+00	892.00
IUUC-Mlu-067386	Myotis lucifugus	81.36	0.00e+00	885.00
IUUC-Nle-069742	Nomascus leucogenys	81.36	0.00e+00	885.00
IUUC-Opr-070705	Ochotona princeps	68.92	0.00e+00	753.00
IUUC-Ont-071537	Oreochromis niloticus	76.02	0.00e+00	835.00
IUUC-Oan-073193	Ornithorhynchus anatinus	82.72	0.00e+00	904.00
IUUC-Ocu-074501	Oryctolagus cuniculus	81.36	0.00e+00	884.00
IUUC-Ola-086726	Oryzias latipes	74.61	0.00e+00	825.00
IUUC-Oga-088069	Otolemur garnettii	80.66	0.00e+00	879.00
IUUC-Oar-090091	Ovis aries	81.36	0.00e+00	885.00
IUUC-Ptr-091409	Pan troglodytes	81.36	0.00e+00	886.00
IUUC-Pan-092268	Papio anubis	81.36	0.00e+00	885.00
IUUC-Psi-093685	Pelodiscus sinensis	80.73	0.00e+00	877.00
IUUC-Pma-094100	Petromyzon marinus	71.01	0.00e+00	687.00
IUUC-Pfo-096217	Poecilia formosa	74.42	0.00e+00	820.00
IUUC-Pab-098601	Pongo abelii	81.36	0.00e+00	885.00
IUUC-Pva-102160	Pteropus vampyrus	72.67	0.00e+00	768.00
IUUC-Rno-105557	Rattus norvegicus	80.97	0.00e+00	884.00
IUUC-Sha-106643	Sarcophilus harrisii	81.17	0.00e+00	885.00
IUUC-Ssc-116317	Sus scrofa	76.25	0.00e+00	817.00
IUUC-Tgu-116865	Taeniopygia guttata	81.94	0.00e+00	890.00
IUUC-Tru-118284	Takifugu rubripes	72.87	0.00e+00	795.00
IUUC-Tsy-119440	Tarsius syrichta	78.83	0.00e+00	842.00
IUUC-Tni-120005	Tetraodon nigroviridis	72.20	0.00e+00	794.00
IUUC-Tbe-128144	Tupaia belangeri	68.61	0.00e+00	648.00
IUUC-Ttr-128481	Tursiops truncatus	70.49	0.00e+00	729.00
IUUC-Xtr-131907	Xenopus tropicalis	71.35	0.00e+00	756.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence