iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000394

Ensembl Protein ID

EMT04082

UniProt Accession

M8BM43; M8BM43_AEGTA

Genbank Protein ID

EMT04082.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

KD599074

Gene Name

F775_27833

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_27833	EMT04082	EMT04082

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.30e-33	116.0	396	823
UBD/Alpha-Helix/UBA	8.90e-11	42.3	700	739

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 41   npkepkgellkslqklfeelw........kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeek 133
           ++ +p+ +l ++++kl + ++        ++ ++ + pr++++++++ ++efs+++qqDa Ef ++l+d++e++                           
   Q: 396  SQADPTLDLNMQMTKLAHGMLsgkysapsQEGQEGIRPRMFKSVIAASHPEFSSMRQQDALEFYHHLIDKVEQAN-------------------------- 470
           33688889************76666666677788*************************************9988.......................... PP
   S: 134  kkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgkeetkke...........................slqdcLesftkeeelegenky 206
           + +++ +   + F++ ++++++c++ + ++ +  ++fl+ls+p+++ ++++++                            l+ cL+sf+  ee+ +   +
   Q: 471  PGNHELN-PCTGFKFIIEERVQCPSGKVSYnQHCDNFLTLSIPLHEATNKEQLeafhekkaamdldgkevskeeivrprvPLEACLASFSGGEEVPE---F 567
           3444444.4568************999888788899*********999776669*****************************************96...* PP
   S: 207  ycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts........................................ 267
           y++  ++k++a k+++lk++P++L+l++  +               +++p+ +d+s++ ++                                        
   Q: 568  YSTALNSKTTAIKTTGLKTFPDYLVLQMHVY---------------IDVPDIIDISHMRSNgvqpgeellpegascgnkaeparpvadedivsqlanigfn 653
           ***************************9998...............3444444444333333333333333333334566666666666666666666666 PP
   S: 268  ............................................peekqke.................................................. 274
                                                       +     +                                                  
   Q: 654  yfacqkaaintsnagleeamnwllshtqdpdinepisqdpmpaeD-----Tideaslqtlvsfgfpedvsrmalkasggnieratewvfshpeasssvsad 749
           666666666666666666666666666555555555555555550.....055555555555555555555566666666666666666666666666777 PP
   S: 275  ................kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                           + +Y+L+a v+H+G s+++GHYva++ + +g+W  f+D+kV ++   +  +   + +Y++f++r
   Q: 750  sstnnvkdddshisdgSGRYKLMAFVSHMGtSTHCGHYVAHILK-DGRWTIFNDNKVAAS--VDLPK---DMGYLYFFQR 823
           7777778888999999****************************.9***********999..68888...999*999997 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLldg 41
           +de  l+ lv+ GF+++  + aL a+++n+e+A+e+++++
   Q: 700  IDEASLQTLVSFGFPEDVSRMALKASGGNIERATEWVFSH 739
           58899*********************************97 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MEVQPEPGRA RLPRGRVDRG DTIPHACCRD CVPVRRRYTA GPRHTKVPRK RGALYMAKFA 60
EANLDIVAVE LEFFAKRDKE CKKKDEKEMD HKNFVERSEG GLYVDMNSFL GFGREHVAWN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGTAC AGCCGGAGCC GGGTCGAGCA CGGCTTCCCC GAGGTAGAGT CGATCGAGGG 60
GACACAATTC CTCACGCTTG TTGTAGGGAT TGTGTTCCTG TGAGGAGAAG GTACACCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ats:F775_27833

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002104	Ailuropoda melanoleuca	44.20	0.00e+00	637.00
IUUC-Atr-002580	Amborella trichopoda	69.34	5.00e-146	511.00
IUUC-Apl-003774	Anas platyrhynchos	44.70	0.00e+00	651.00
IUUC-Aca-005368	Anolis carolinensis	46.19	0.00e+00	668.00
IUUC-Aly-005727	Arabidopsis lyrata	63.81	0.00e+00	986.00
IUUC-Ath-006974	Arabidopsis thaliana	64.46	0.00e+00	990.00
IUUC-Ago-007890	Ashbya gossypii	26.94	1.00e-60	227.00
IUUC-Acl-008057	Aspergillus clavatus	32.19	6.00e-101	361.00
IUUC-Afl-008547	Aspergillus flavus	32.65	4.00e-93	335.00
IUUC-Afu-008805	Aspergillus fumigatus	33.22	2.00e-84	306.00
IUUC-Ani-009441	Aspergillus nidulans	33.01	7.00e-75	274.00
IUUC-Ang-009720	Aspergillus niger	31.89	7.00e-87	314.00
IUUC-Aor-010111	Aspergillus oryzae	31.89	2.00e-98	352.00
IUUC-Ate-010531	Aspergillus terreus	30.84	1.00e-78	287.00
IUUC-Ame-011470	Astyanax mexicanus	39.30	1.00e-163	569.00
IUUC-Bgr-012183	Blumeria graminis	31.05	8.00e-90	324.00
IUUC-Bta-013179	Bos taurus	44.67	0.00e+00	640.00
IUUC-Bci-013858	Botrytis cinerea	32.22	2.00e-92	333.00
IUUC-Bdi-014904	Brachypodium distachyon	84.67	0.00e+00	1285.00
IUUC-Bol-015536	Brassica oleracea	63.99	0.00e+00	974.00
IUUC-Bra-017619	Brassica rapa	63.04	0.00e+00	969.00
IUUC-Cel-018625	Caenorhabditis elegans	32.10	3.00e-100	358.00
IUUC-Cja-019063	Callithrix jacchus	43.72	0.00e+00	630.00
IUUC-Cfa-020976	Canis familiaris	45.58	0.00e+00	654.00
IUUC-Cpo-022265	Cavia porcellus	45.47	0.00e+00	653.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	41.60	5.00e-111	394.00
IUUC-Csa-024078	Chlorocebus sabaeus	39.95	1.00e-165	576.00
IUUC-Cho-024702	Choloepus hoffmanni	37.52	4.00e-94	338.00
IUUC-Cin-025411	Ciona intestinalis	40.30	4.00e-153	534.00
IUUC-Csv-026347	Ciona savignyi	39.32	1.00e-148	519.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	32.08	4.00e-84	305.00
IUUC-Cne-026831	Cryptococcus neoformans	32.92	1.00e-94	340.00
IUUC-Cme-027335	Cyanidioschyzon merolae	32.39	6.00e-29	122.00
IUUC-Dre-027651	Danio rerio	40.84	8.00e-177	613.00
IUUC-Dno-029034	Dasypus novemcinctus	44.59	0.00e+00	644.00
IUUC-Dor-030130	Dipodomys ordii	35.23	9.00e-91	327.00
IUUC-Dse-031467	Dothistroma septosporum	32.81	1.00e-94	340.00
IUUC-Dme-032075	Drosophila melanogaster	42.07	7.00e-164	570.00
IUUC-Ete-032865	Echinops telfairi	41.57	3.00e-164	571.00
IUUC-Eca-034059	Equus caballus	44.43	0.00e+00	640.00
IUUC-Eeu-035304	Erinaceus europaeus	44.26	7.00e-169	587.00
IUUC-Fca-035515	Felis catus	44.55	0.00e+00	646.00
IUUC-Fal-037271	Ficedula albicollis	45.27	0.00e+00	636.00
IUUC-Fox-037745	Fusarium oxysporum	32.95	2.00e-96	345.00
IUUC-Fso-038158	Fusarium solani	31.96	1.00e-92	333.00
IUUC-Gmo-039071	Gadus morhua	41.77	2.00e-157	548.00
IUUC-Ggr-040098	Gaeumannomyces graminis	31.56	4.00e-91	328.00
IUUC-Gga-040635	Gallus gallus	44.30	0.00e+00	650.00
IUUC-Gac-042528	Gasterosteus aculeatus	40.07	3.00e-159	555.00
IUUC-Gma-043614	Glycine max	62.24	0.00e+00	944.00
IUUC-Ggo-044602	Gorilla gorilla	44.43	0.00e+00	642.00
IUUC-Hsa-045959	Homo sapiens	44.43	0.00e+00	642.00
IUUC-Hvu-047563	Hordeum vulgare	90.98	0.00e+00	1153.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	44.07	0.00e+00	647.00
IUUC-Kpa-049156	Komagataella pastoris	30.16	8.00e-90	324.00
IUUC-Lch-049648	Latimeria chalumnae	44.00	0.00e+00	643.00
IUUC-Lpe-051523	Leersia perrieri	81.32	0.00e+00	1253.00
IUUC-Loc-052072	Lepisosteus oculatus	40.81	3.00e-167	581.00
IUUC-Lma-053216	Leptosphaeria maculans	32.64	3.00e-91	330.00
IUUC-Laf-054327	Loxodonta africana	44.31	0.00e+00	644.00
IUUC-Mcc-055443	Macaca mulatta	44.43	0.00e+00	639.00
IUUC-Meu-056298	Macropus eugenii	46.59	4.00e-126	444.00
IUUC-Mor-057106	Magnaporthe oryzae	32.59	6.00e-96	344.00
IUUC-Mpo-057589	Magnaporthe poae	31.82	2.00e-91	330.00
IUUC-Mtr-058680	Medicago truncatula	61.68	0.00e+00	968.00
IUUC-Mla-058903	Melampsora laricipopulina	31.24	1.00e-84	306.00
IUUC-Mga-059669	Meleagris gallopavo	44.34	0.00e+00	640.00
IUUC-Mvi-060476	Microbotryum violaceum	32.24	1.00e-83	303.00
IUUC-Mmr-060575	Microcebus murinus	44.55	0.00e+00	639.00
IUUC-Mdo-062183	Monodelphis domestica	44.06	0.00e+00	640.00
IUUC-Mmu-063592	Mus musculus	44.55	0.00e+00	643.00
IUUC-Mac-065634	Musa acuminata	61.64	0.00e+00	1000.00
IUUC-Mpu-066082	Mustela putorius furo	45.33	0.00e+00	646.00
IUUC-Mlu-067345	Myotis lucifugus	43.72	0.00e+00	635.00
IUUC-Nfi-068558	Neosartorya fischeri	32.12	1.00e-95	343.00
IUUC-Ncr-068960	Neurospora crassa	30.09	1.00e-82	300.00
IUUC-Nle-070173	Nomascus leucogenys	45.83	0.00e+00	650.00
IUUC-Opr-070556	Ochotona princeps	43.95	0.00e+00	650.00
IUUC-Ont-071502	Oreochromis niloticus	42.96	5.00e-161	560.00
IUUC-Oan-072959	Ornithorhynchus anatinus	47.70	2.00e-61	227.00
IUUC-Ocu-074861	Oryctolagus cuniculus	45.08	0.00e+00	658.00
IUUC-Oba-075109	Oryza barthii	83.98	0.00e+00	1281.00
IUUC-Obr-076292	Oryza brachyantha	80.73	0.00e+00	1201.00
IUUC-Ogl-077065	Oryza glaberrima	82.02	0.00e+00	1271.00
IUUC-Ogu-078776	Oryza glumaepatula	85.25	0.00e+00	1299.00
IUUC-Oin-080048	Oryza indica	81.63	0.00e+00	1261.00
IUUC-Olo-080711	Oryza longistaminata	82.02	0.00e+00	1248.00
IUUC-Ome-081506	Oryza meridionalis	83.92	0.00e+00	1260.00
IUUC-Oni-082320	Oryza nivara	81.46	0.00e+00	1269.00
IUUC-Opu-083801	Oryza punctata	83.98	0.00e+00	1250.00
IUUC-Oru-085139	Oryza rufipogon	81.33	0.00e+00	1265.00
IUUC-Osa-085713	Oryza sativa	82.02	0.00e+00	1273.00
IUUC-Ola-086951	Oryzias latipes	40.31	1.00e-155	542.00
IUUC-Olu-087822	Ostreococcus lucimarinus	40.51	8.00e-146	510.00
IUUC-Oga-088625	Otolemur garnettii	43.64	0.00e+00	638.00
IUUC-Oar-089995	Ovis aries	43.77	0.00e+00	632.00
IUUC-Ptr-090640	Pan troglodytes	43.46	0.00e+00	639.00
IUUC-Pan-091974	Papio anubis	43.60	0.00e+00	633.00
IUUC-Psi-093957	Pelodiscus sinensis	44.19	0.00e+00	660.00
IUUC-Pma-094242	Petromyzon marinus	41.30	4.00e-81	294.00
IUUC-Pno-094835	Phaeosphaeria nodorum	32.48	3.00e-85	308.00
IUUC-Ppa-095901	Physcomitrella patens	57.22	0.00e+00	888.00
IUUC-Pfo-097148	Poecilia formosa	41.37	4.00e-160	558.00
IUUC-Pab-098672	Pongo abelii	39.58	3.00e-157	548.00
IUUC-Pop-098943	Populus trichocarpa	64.17	0.00e+00	971.00
IUUC-Pca-100738	Procavia capensis	40.99	2.00e-121	429.00
IUUC-Ppe-101315	Prunus persica	62.90	0.00e+00	969.00
IUUC-Pva-102154	Pteropus vampyrus	43.70	0.00e+00	628.00
IUUC-Pgr-103343	Puccinia graminis	30.38	1.00e-74	273.00
IUUC-Ptt-103928	Puccinia triticina	29.66	4.00e-68	252.00
IUUC-Pte-104306	Pyrenophora teres	32.45	2.00e-77	283.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	32.45	1.00e-80	293.00
IUUC-Rno-105801	Rattus norvegicus	44.67	0.00e+00	646.00
IUUC-Sce-106304	Saccharomyces cerevisiae	29.80	2.00e-63	236.00
IUUC-Sha-107635	Sarcophilus harrisii	45.42	0.00e+00	648.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	31.68	2.00e-84	306.00
IUUC-Spo-108144	Schizosaccharomyces pombe	31.22	5.00e-92	331.00
IUUC-Smo-108848	Selaginella moellendorffii	56.15	0.00e+00	815.00
IUUC-Sit-110728	Setaria italica	81.26	0.00e+00	1256.00
IUUC-Sly-111523	Solanum lycopersicum	62.79	0.00e+00	987.00
IUUC-Sar-113733	Sorex araneus	43.49	8.00e-86	311.00
IUUC-Sbi-114419	Sorghum bicolor	81.00	0.00e+00	1238.00
IUUC-Sre-115225	Sporisorium reilianum	30.87	2.00e-88	319.00
IUUC-Ssc-115686	Sus scrofa	43.46	0.00e+00	640.00
IUUC-Tgu-117346	Taeniopygia guttata	44.24	0.00e+00	634.00
IUUC-Tru-118627	Takifugu rubripes	39.69	3.00e-167	581.00
IUUC-Tsy-119278	Tarsius syrichta	36.74	9.00e-147	513.00
IUUC-Tni-120658	Tetraodon nigroviridis	40.24	9.00e-154	536.00
IUUC-Tca-121585	Theobroma cacao	63.37	0.00e+00	965.00
IUUC-Tre-122043	Trichoderma reesei	32.36	2.00e-93	335.00
IUUC-Tvi-122303	Trichoderma virens	32.78	4.00e-90	325.00
IUUC-Tae-125686	Triticum aestivum	94.36	0.00e+00	1449.00
IUUC-Tur-126732	Triticum urartu	98.63	0.00e+00	1481.00
IUUC-Tme-126909	Tuber melanosporum	32.56	2.00e-84	306.00
IUUC-Tbe-127261	Tupaia belangeri	36.75	7.00e-98	351.00
IUUC-Ttr-129119	Tursiops truncatus	53.38	3.00e-89	322.00
IUUC-Uma-129599	Ustilago maydis	31.87	3.00e-94	339.00
IUUC-Vda-129688	Verticillium dahliae	32.01	2.00e-91	329.00
IUUC-Vpa-130170	Vicugna pacos	33.98	5.00e-127	447.00
IUUC-Vvi-131116	Vitis vinifera	65.85	0.00e+00	980.00
IUUC-Xtr-131953	Xenopus tropicalis	43.08	1.00e-173	603.00
IUUC-Xma-133837	Xiphophorus maculatus	41.24	1.00e-159	556.00
IUUC-Yli-134510	Yarrowia lipolytica	30.65	6.00e-89	321.00
IUUC-Zma-135786	Zea mays	79.29	0.00e+00	1185.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence