iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-065670

Ensembl Protein ID

GSMUA_Achr2P09260_001

UniProt Accession

M0S6G7; M0S6G7_MUSAM

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr2G09260_001	GSMUA_Achr2T09260_001	GSMUA_Achr2P09260_001

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	35.44	4.00e-41	166.00	IUUC-Hsa-046357
E3 activity/RING/RING	35.44	2.00e-41	166.00	IUUC-Mmu-064129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Musa acuminata

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MESDSIECVS SIDGIDEEAT SLPHHSSKSH GGAAPPAGIV PSTSVHELLE CPVCTNSMYP 60
PIHQCQNGHT LCSTCKTRVH NRCPTCRQEL GDIRCLALEK VAESLELPCK YYSLGCPEIF 120

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Nucleotide Sequence
(Fasta)

ATGGAGTCGG ATAGCATCGA ATGCGTGTCG TCGATCGACG GGATAGATGA GGAGGCGACC 60
TCCCTTCCCC ACCACTCCTC GAAGTCCCAC GGAGGCGCTG CGCCTCCCGC CGGGATCGTC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mus:103975958

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001186	Ailuropoda melanoleuca	36.07	2.00e-42	165.00
IUUC-Atr-003118	Amborella trichopoda	83.90	1.00e-137	481.00
IUUC-Apl-003813	Anas platyrhynchos	36.07	2.00e-42	165.00
IUUC-Aly-006522	Arabidopsis lyrata	78.22	6.00e-151	525.00
IUUC-Ath-007092	Arabidopsis thaliana	79.38	5.00e-153	533.00
IUUC-Bta-012887	Bos taurus	36.07	2.00e-42	165.00
IUUC-Bdi-014729	Brachypodium distachyon	78.53	5.00e-157	546.00
IUUC-Bol-015983	Brassica oleracea	78.19	8.00e-152	528.00
IUUC-Bra-016910	Brassica rapa	79.06	2.00e-153	534.00
IUUC-Cja-019796	Callithrix jacchus	35.44	1.00e-42	166.00
IUUC-Cpo-022348	Cavia porcellus	35.44	8.00e-43	166.00
IUUC-Csa-023974	Chlorocebus sabaeus	35.44	1.00e-42	166.00
IUUC-Dno-029764	Dasypus novemcinctus	36.07	2.00e-42	165.00
IUUC-Dme-031755	Drosophila melanogaster	35.69	3.00e-37	148.00
IUUC-Eca-033536	Equus caballus	36.07	2.00e-42	165.00
IUUC-Fca-035362	Felis catus	36.07	2.00e-42	165.00
IUUC-Fal-037487	Ficedula albicollis	36.07	1.00e-42	166.00
IUUC-Gga-040269	Gallus gallus	36.07	2.00e-42	165.00
IUUC-Gac-042282	Gasterosteus aculeatus	35.79	3.00e-43	168.00
IUUC-Gma-042926	Glycine max	79.23	4.00e-137	479.00
IUUC-Ggo-045444	Gorilla gorilla	35.44	1.00e-42	166.00
IUUC-Hsa-046357	Homo sapiens	35.44	1.00e-42	166.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	35.44	8.00e-43	166.00
IUUC-Lch-049504	Latimeria chalumnae	36.07	1.00e-42	165.00
IUUC-Lpe-050879	Leersia perrieri	72.97	8.00e-126	442.00
IUUC-Laf-053668	Loxodonta africana	36.07	2.00e-42	165.00
IUUC-Mcc-054640	Macaca mulatta	35.44	1.00e-42	166.00
IUUC-Mtr-058699	Medicago truncatula	84.31	3.00e-163	566.00
IUUC-Mga-059503	Meleagris gallopavo	35.54	2.00e-42	165.00
IUUC-Mmr-060794	Microcebus murinus	35.44	8.00e-43	166.00
IUUC-Mmu-064129	Mus musculus	35.44	6.00e-43	166.00
IUUC-Mpu-066488	Mustela putorius furo	36.07	2.00e-42	165.00
IUUC-Mlu-067207	Myotis lucifugus	35.76	9.00e-43	166.00
IUUC-Nle-069706	Nomascus leucogenys	35.44	1.00e-42	166.00
IUUC-Ont-071849	Oreochromis niloticus	35.79	2.00e-43	168.00
IUUC-Ocu-074876	Oryctolagus cuniculus	35.44	1.00e-42	166.00
IUUC-Oba-075289	Oryza barthii	92.19	1.00e-143	502.00
IUUC-Obr-076037	Oryza brachyantha	80.00	1.00e-133	468.00
IUUC-Ogl-077148	Oryza glaberrima	80.00	2.00e-133	467.00
IUUC-Ogu-078042	Oryza glumaepatula	80.00	1.00e-133	468.00
IUUC-Oin-079325	Oryza indica	80.00	2.00e-133	467.00
IUUC-Olo-080244	Oryza longistaminata	80.00	1.00e-133	469.00
IUUC-Ome-081318	Oryza meridionalis	81.10	3.00e-125	440.00
IUUC-Oni-082163	Oryza nivara	80.00	2.00e-133	467.00
IUUC-Opu-084065	Oryza punctata	80.71	7.00e-125	439.00
IUUC-Oru-084833	Oryza rufipogon	80.00	2.00e-133	467.00
IUUC-Osa-085316	Oryza sativa	80.00	2.00e-133	467.00
IUUC-Ola-086814	Oryzias latipes	35.79	3.00e-43	168.00
IUUC-Oga-088399	Otolemur garnettii	35.44	8.00e-43	166.00
IUUC-Oar-089323	Ovis aries	36.07	2.00e-42	165.00
IUUC-Ptr-090692	Pan troglodytes	35.44	1.00e-42	166.00
IUUC-Pan-092012	Papio anubis	35.44	1.00e-42	166.00
IUUC-Psi-093687	Pelodiscus sinensis	36.07	2.00e-42	165.00
IUUC-Ppa-095212	Physcomitrella patens	88.01	9.00e-144	501.00
IUUC-Pfo-097134	Poecilia formosa	35.79	3.00e-43	168.00
IUUC-Pab-097555	Pongo abelii	35.44	1.00e-42	166.00
IUUC-Pop-100033	Populus trichocarpa	81.33	3.00e-159	553.00
IUUC-Ppe-101960	Prunus persica	82.88	2.00e-165	573.00
IUUC-Pva-103132	Pteropus vampyrus	26.85	1.00e-10	59.30
IUUC-Rno-104866	Rattus norvegicus	35.44	6.00e-43	166.00
IUUC-Sha-106547	Sarcophilus harrisii	36.07	3.00e-42	165.00
IUUC-Smo-109412	Selaginella moellendorffii	79.33	2.00e-144	504.00
IUUC-Sit-110245	Setaria italica	80.83	1.00e-132	465.00
IUUC-Sly-111259	Solanum lycopersicum	80.66	6.00e-157	545.00
IUUC-Stu-112571	Solanum tuberosum	79.88	3.00e-156	543.00
IUUC-Sbi-114035	Sorghum bicolor	80.37	7.00e-134	469.00
IUUC-Tgu-116579	Taeniopygia guttata	36.07	2.00e-42	165.00
IUUC-Tca-121517	Theobroma cacao	82.54	3.00e-164	570.00
IUUC-Tur-126259	Triticum urartu	82.13	2.00e-133	467.00
IUUC-Vvi-131233	Vitis vinifera	79.20	2.00e-133	468.00
IUUC-Xtr-132553	Xenopus tropicalis	35.09	1.00e-42	166.00
IUUC-Xma-133670	Xiphophorus maculatus	35.79	3.00e-43	168.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence