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Tag Content
UUCD2 ID IUUC-Ola-086814
UUCD1 version UUC-OrL-00619
Ensembl Protein ID ENSORLP00000017018.1
UniProt Accession H2MEL0; H2MEL0_ORYLA
Genbank Protein ID ENSORLP00000017018
Protein Name E3 ubiquitin-protein ligase
Genbank Nucleotide ID BAAF04008192
Gene Name n4bp1; siah1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSORLG00000013569.1 ENSORLT00000017016.1 ENSORLP00000017015.1
ENSORLG00000013569.1 ENSORLT00000017019.1 ENSORLP00000017018.1
ENSORLG00000013569.1 ENSORLT00000017024.1 ENSORLP00000017023.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 82.35 2.00e-126 448.00 IUUC-Dme-031700
E3 activity/RING/RING 97.52 2.00e-166 582.00 IUUC-Hsa-046357
E3 activity/RING/RING 97.87 1.00e-166 582.00 IUUC-Mmu-064129
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Oryzias latipes
Functional Description
(View)

Functional Description


     E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
 E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Protein Sequence
(Fasta)
MSRQTATALP TGTSKCPPSQ RVPTLSGTTA SNSDLASLFE CPVCFDYVLP PILQCQSGHL 60
VCSNCRPKLT CCPTCRGPLG SIRNLAMEKV ANSVLFPCKY ASSGCEVTLP HTDKTEHEEL 120
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Protein Fasta Sequence


>IUUC-Ola-086814|E3,RING|Oryzias latipes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGGCCGCCG GAAGGCAGCA GACGGAGGCC GCCACCACCG TGGACGAGTT CACCGTCCTG 60
GAGGATAAAG AAGAGGAGCT GAAATGCGCC AAGCCGCGCG TGGAACAGGT TTTTAAGGTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ola-086814|E3,RING|Oryzias latipes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH
PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH
Pfam

PF03145--Sina
Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000061 Aegilops tauschii 37.36 4.00e-45 174.00
IUUC-Aml-001186 Ailuropoda melanoleuca 97.16 9.00e-167 578.00
IUUC-Atr-002857 Amborella trichopoda 36.57 6.00e-45 174.00
IUUC-Apl-003813 Anas platyrhynchos 97.16 1.00e-166 578.00
IUUC-Aca-005014 Anolis carolinensis 97.16 7.00e-167 579.00
IUUC-Aly-006522 Arabidopsis lyrata 37.35 1.00e-41 163.00
IUUC-Ath-007049 Arabidopsis thaliana 33.45 6.00e-42 164.00
IUUC-Ame-011196 Astyanax mexicanus 98.94 3.00e-169 587.00
IUUC-Bta-012887 Bos taurus 97.16 9.00e-167 578.00
IUUC-Bdi-014200 Brachypodium distachyon 37.73 2.00e-45 176.00
IUUC-Bol-016263 Brassica oleracea 33.81 1.00e-42 166.00
IUUC-Bra-016910 Brassica rapa 36.82 8.00e-42 163.00
IUUC-Cel-018320 Caenorhabditis elegans 72.37 6.00e-116 410.00
IUUC-Cja-019796 Callithrix jacchus 97.52 2.00e-167 580.00
IUUC-Cfa-020642 Canis familiaris 97.16 1.00e-167 582.00
IUUC-Cpo-022348 Cavia porcellus 97.52 1.00e-167 581.00
IUUC-Csa-023974 Chlorocebus sabaeus 97.52 1.00e-167 582.00
IUUC-Cho-024933 Choloepus hoffmanni 84.92 2.00e-130 457.00
IUUC-Cin-025674 Ciona intestinalis 78.72 5.00e-135 473.00
IUUC-Csv-026233 Ciona savignyi 85.04 2.00e-132 464.00
IUUC-Dre-028041 Danio rerio 99.29 3.00e-170 590.00
IUUC-Dno-029764 Dasypus novemcinctus 97.16 1.00e-166 578.00
IUUC-Dor-030489 Dipodomys ordii 84.70 2.00e-94 337.00
IUUC-Dme-031700 Drosophila melanogaster 84.27 6.00e-120 423.00
IUUC-Ete-032423 Echinops telfairi 96.62 5.00e-156 543.00
IUUC-Eca-033536 Equus caballus 97.16 1.00e-166 578.00
IUUC-Eeu-035314 Erinaceus europaeus 96.62 4.00e-156 543.00
IUUC-Fca-035362 Felis catus 97.16 7.00e-167 579.00
IUUC-Fal-037487 Ficedula albicollis 97.16 1.00e-166 578.00
IUUC-Gmo-039091 Gadus morhua 83.67 1.00e-128 452.00
IUUC-Gga-040269 Gallus gallus 97.16 1.00e-166 578.00
IUUC-Gac-042282 Gasterosteus aculeatus 100.00 2.00e-170 590.00
IUUC-Gma-042926 Glycine max 34.04 7.00e-41 160.00
IUUC-Ggo-045444 Gorilla gorilla 97.52 1.00e-167 582.00
IUUC-Hsa-046357 Homo sapiens 97.52 1.00e-167 582.00
IUUC-Hvu-047574 Hordeum vulgare 37.00 5.00e-45 174.00
IUUC-Itr-048046 Ictidomys tridecemlineatus 97.52 1.00e-167 581.00
IUUC-Lch-049504 Latimeria chalumnae 97.16 1.00e-166 578.00
IUUC-Lpe-050879 Leersia perrieri 40.25 8.00e-43 167.00
IUUC-Loc-052191 Lepisosteus oculatus 97.52 5.00e-167 579.00
IUUC-Laf-053668 Loxodonta africana 97.16 1.00e-166 578.00
IUUC-Mcc-054640 Macaca mulatta 97.52 1.00e-167 582.00
IUUC-Meu-055922 Macropus eugenii 83.33 4.00e-127 446.00
IUUC-Mtr-058747 Medicago truncatula 34.81 2.00e-42 165.00
IUUC-Mga-059503 Meleagris gallopavo 97.16 6.00e-167 579.00
IUUC-Mmr-060794 Microcebus murinus 97.52 1.00e-167 581.00
IUUC-Mdo-061971 Monodelphis domestica 84.92 4.00e-130 456.00
IUUC-Mmu-064129 Mus musculus 97.87 7.00e-168 582.00
IUUC-Mac-065670 Musa acuminata 35.79 4.00e-43 168.00
IUUC-Mpu-066488 Mustela putorius furo 97.16 1.00e-166 578.00
IUUC-Mlu-067207 Myotis lucifugus 97.16 4.00e-167 580.00
IUUC-Nle-069706 Nomascus leucogenys 97.52 1.00e-167 581.00
IUUC-Opr-070341 Ochotona princeps 55.56 4.00e-49 187.00
IUUC-Ont-071849 Oreochromis niloticus 100.00 2.00e-170 590.00
IUUC-Oan-073701 Ornithorhynchus anatinus 52.56 5.00e-49 187.00
IUUC-Ocu-074876 Oryctolagus cuniculus 97.52 2.00e-167 581.00
IUUC-Oba-075454 Oryza barthii 40.66 4.00e-43 168.00
IUUC-Obr-076037 Oryza brachyantha 35.43 1.00e-40 159.00
IUUC-Ogl-077712 Oryza glaberrima 40.66 4.00e-43 168.00
IUUC-Ogu-078910 Oryza glumaepatula 40.83 7.00e-43 167.00
IUUC-Oin-079749 Oryza indica 40.66 4.00e-43 168.00
IUUC-Olo-080244 Oryza longistaminata 35.43 1.00e-40 160.00
IUUC-Ome-081318 Oryza meridionalis 40.66 4.00e-43 167.00
IUUC-Oni-083109 Oryza nivara 40.66 4.00e-43 168.00
IUUC-Opu-084065 Oryza punctata 41.08 2.00e-43 169.00
IUUC-Oru-084785 Oryza rufipogon 40.66 4.00e-43 168.00
IUUC-Osa-085610 Oryza sativa 40.66 4.00e-43 168.00
IUUC-Oga-088399 Otolemur garnettii 97.52 1.00e-167 581.00
IUUC-Oar-089323 Ovis aries 97.16 1.00e-166 578.00
IUUC-Ptr-090692 Pan troglodytes 97.52 9.00e-168 582.00
IUUC-Pan-092012 Papio anubis 97.52 1.00e-167 582.00
IUUC-Psi-093687 Pelodiscus sinensis 97.16 5.00e-167 579.00
IUUC-Pma-094387 Petromyzon marinus 92.58 1.00e-157 548.00
IUUC-Ppa-095212 Physcomitrella patens 35.82 8.00e-41 160.00
IUUC-Pfo-097134 Poecilia formosa 100.00 2.00e-170 590.00
IUUC-Pab-097555 Pongo abelii 97.52 1.00e-167 582.00
IUUC-Pop-099970 Populus trichocarpa 35.29 8.00e-45 173.00
IUUC-Pca-100328 Procavia capensis 84.00 2.00e-126 445.00
IUUC-Ppe-101760 Prunus persica 36.10 2.00e-43 169.00
IUUC-Pva-102368 Pteropus vampyrus 90.00 9.00e-57 213.00
IUUC-Rno-104866 Rattus norvegicus 97.87 7.00e-168 582.00
IUUC-Sha-106547 Sarcophilus harrisii 97.16 9.00e-167 578.00
IUUC-Smo-109412 Selaginella moellendorffii 34.28 7.00e-40 157.00
IUUC-Sit-110595 Setaria italica 37.11 2.00e-42 165.00
IUUC-Sly-111259 Solanum lycopersicum 36.76 9.00e-42 163.00
IUUC-Stu-112571 Solanum tuberosum 36.76 8.00e-42 164.00
IUUC-Sbi-114090 Sorghum bicolor 37.50 3.00e-43 168.00
IUUC-Ssc-116441 Sus scrofa 85.20 6.00e-130 456.00
IUUC-Tgu-116579 Taeniopygia guttata 97.16 1.00e-166 578.00
IUUC-Tru-118250 Takifugu rubripes 94.68 3.00e-160 556.00
IUUC-Tsy-119548 Tarsius syrichta 81.68 7.00e-60 223.00
IUUC-Tni-120488 Tetraodon nigroviridis 98.94 5.00e-166 576.00
IUUC-Tca-121228 Theobroma cacao 36.61 1.00e-41 163.00
IUUC-Tae-123647 Triticum aestivum 37.36 4.00e-45 174.00
IUUC-Tur-126259 Triticum urartu 35.11 9.00e-40 157.00
IUUC-Ttr-129166 Tursiops truncatus 96.68 2.00e-140 491.00
IUUC-Vpa-130799 Vicugna pacos 88.30 1.00e-91 328.00
IUUC-Vvi-131451 Vitis vinifera 37.86 5.00e-42 164.00
IUUC-Xtr-132553 Xenopus tropicalis 97.52 2.00e-167 581.00
IUUC-Xma-133670 Xiphophorus maculatus 100.00 2.00e-170 590.00
Created Date 25-Jun-2017

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