iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107612

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01222348

Gene Name

AMBRA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000015742.1	ENSSHAT00000018700.1	ENSSHAP00000018546.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-07	31.5	93	126

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           gH    +c+ f ++  +l++sG+ Dg +++WDl+
   Q: 93   GHRRTPWCVTFhPTipGLIASGCLDGEVRIWDLH 126
           6777779*****66679***************97 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MKVVPEKNAV RILWGRERGT RALGAQRLLQ ELVEDKTRWM KWEGKKVELP DSPRSTFLLA 60
FSPDRTLMAS THVNHNIYIT EVKTGKCVHS LVGHRRTPWC VTFHPTIPGL IASGCLDGEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGGTTG TCCCCGAGAA GAATGCTGTC CGGATACTGT GGGGTCGAGA AAGGGGCACG 60
CGAGCCTTGG GGGCTCAGCG GCTTCTACAG GAGCTGGTGG AGGATAAAAC TCGGTGGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0045335--C:phagocytic vesicle
GO:0006914--P:autophagy
GO:0008285--P:negative regulation of cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0021915--P:neural tube development
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:2000785--P:regulation of autophagosome assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001917	Ailuropoda melanoleuca	88.40	0.00e+00	1641.00
IUUC-Atr-002557	Amborella trichopoda	37.74	1.00e-30	128.00
IUUC-Apl-004186	Anas platyrhynchos	84.11	0.00e+00	1970.00
IUUC-Aca-004419	Anolis carolinensis	76.41	0.00e+00	1796.00
IUUC-Aly-006308	Arabidopsis lyrata	37.61	9.00e-29	122.00
IUUC-Ath-007656	Arabidopsis thaliana	36.45	2.00e-28	120.00
IUUC-Ame-011354	Astyanax mexicanus	60.56	0.00e+00	1242.00
IUUC-Bta-012455	Bos taurus	85.54	0.00e+00	1998.00
IUUC-Bdi-014580	Brachypodium distachyon	41.72	4.00e-30	126.00
IUUC-Bol-016094	Brassica oleracea	39.67	6.00e-29	122.00
IUUC-Bra-017308	Brassica rapa	40.22	7.00e-30	125.00
IUUC-Cja-019073	Callithrix jacchus	95.31	3.00e-150	525.00
IUUC-Cfa-020994	Canis familiaris	87.56	0.00e+00	1366.00
IUUC-Cpo-022101	Cavia porcellus	87.16	0.00e+00	1954.00
IUUC-Csa-023273	Chlorocebus sabaeus	84.32	0.00e+00	1430.00
IUUC-Cin-025567	Ciona intestinalis	52.68	1.00e-55	211.00
IUUC-Csv-026005	Ciona savignyi	52.46	9.00e-55	206.00
IUUC-Dre-028282	Danio rerio	59.05	0.00e+00	1286.00
IUUC-Dno-029948	Dasypus novemcinctus	84.81	0.00e+00	1984.00
IUUC-Dor-030568	Dipodomys ordii	84.44	0.00e+00	1093.00
IUUC-Ete-032864	Echinops telfairi	83.33	0.00e+00	1073.00
IUUC-Eca-034392	Equus caballus	84.12	0.00e+00	1432.00
IUUC-Eeu-034440	Erinaceus europaeus	77.35	0.00e+00	1101.00
IUUC-Fca-035359	Felis catus	83.12	0.00e+00	1945.00
IUUC-Fal-037483	Ficedula albicollis	83.95	0.00e+00	2021.00
IUUC-Gmo-039343	Gadus morhua	75.09	0.00e+00	766.00
IUUC-Gga-040787	Gallus gallus	85.13	0.00e+00	1289.00
IUUC-Gac-041321	Gasterosteus aculeatus	63.40	0.00e+00	1372.00
IUUC-Gma-044022	Glycine max	37.62	6.00e-31	129.00
IUUC-Ggo-044775	Gorilla gorilla	86.30	0.00e+00	969.00
IUUC-Hsa-045708	Homo sapiens	85.61	0.00e+00	2022.00
IUUC-Hvu-047536	Hordeum vulgare	42.17	3.00e-31	129.00
IUUC-Itr-048376	Ictidomys tridecemlineatus	84.94	0.00e+00	1103.00
IUUC-Lch-050255	Latimeria chalumnae	71.07	0.00e+00	1436.00
IUUC-Lpe-050684	Leersia perrieri	41.76	7.00e-32	132.00
IUUC-Loc-052881	Lepisosteus oculatus	67.36	0.00e+00	1498.00
IUUC-Laf-053342	Loxodonta africana	85.02	0.00e+00	743.00
IUUC-Mcc-055848	Macaca mulatta	83.50	0.00e+00	1996.00
IUUC-Meu-056320	Macropus eugenii	94.81	0.00e+00	1238.00
IUUC-Mtr-058484	Medicago truncatula	38.54	2.00e-30	127.00
IUUC-Mga-059401	Meleagris gallopavo	87.68	0.00e+00	1725.00
IUUC-Mmr-061037	Microcebus murinus	87.66	0.00e+00	1973.00
IUUC-Mdo-062484	Monodelphis domestica	83.22	0.00e+00	1896.00
IUUC-Mmu-064090	Mus musculus	84.14	0.00e+00	1969.00
IUUC-Mac-065308	Musa acuminata	42.05	2.00e-30	127.00
IUUC-Mpu-066165	Mustela putorius furo	84.71	0.00e+00	1371.00
IUUC-Mlu-068038	Myotis lucifugus	84.19	0.00e+00	2011.00
IUUC-Nle-069361	Nomascus leucogenys	89.42	0.00e+00	1801.00
IUUC-Opr-070360	Ochotona princeps	90.67	0.00e+00	781.00
IUUC-Ont-071277	Oreochromis niloticus	63.60	0.00e+00	1367.00
IUUC-Oan-073623	Ornithorhynchus anatinus	85.15	0.00e+00	1086.00
IUUC-Ocu-074600	Oryctolagus cuniculus	89.08	0.00e+00	1299.00
IUUC-Oba-075024	Oryza barthii	43.02	7.00e-34	139.00
IUUC-Obr-076172	Oryza brachyantha	37.67	4.00e-34	139.00
IUUC-Ogl-077411	Oryza glaberrima	43.02	1.00e-33	138.00
IUUC-Ogu-078025	Oryza glumaepatula	43.02	1.00e-33	139.00
IUUC-Oni-082463	Oryza nivara	43.02	7.00e-34	139.00
IUUC-Opu-084041	Oryza punctata	43.02	2.00e-33	137.00
IUUC-Oru-085075	Oryza rufipogon	43.02	3.00e-33	137.00
IUUC-Osa-085781	Oryza sativa	43.02	1.00e-33	138.00
IUUC-Ola-086729	Oryzias latipes	63.86	0.00e+00	1386.00
IUUC-Olu-087735	Ostreococcus lucimarinus	39.52	5.00e-24	105.00
IUUC-Oga-089113	Otolemur garnettii	84.08	0.00e+00	1922.00
IUUC-Oar-090171	Ovis aries	88.21	0.00e+00	1930.00
IUUC-Ptr-090970	Pan troglodytes	85.68	0.00e+00	2024.00
IUUC-Pan-092778	Papio anubis	84.21	0.00e+00	1436.00
IUUC-Psi-093571	Pelodiscus sinensis	82.94	0.00e+00	1982.00
IUUC-Pma-094563	Petromyzon marinus	74.58	4.00e-106	377.00
IUUC-Ppa-095832	Physcomitrella patens	36.24	2.00e-30	127.00
IUUC-Pfo-097365	Poecilia formosa	62.15	0.00e+00	1303.00
IUUC-Pab-098647	Pongo abelii	84.84	0.00e+00	1098.00
IUUC-Pop-099742	Populus trichocarpa	40.86	5.00e-31	129.00
IUUC-Pca-101035	Procavia capensis	80.74	0.00e+00	1047.00
IUUC-Ppe-101783	Prunus persica	42.78	6.00e-31	129.00
IUUC-Pva-103187	Pteropus vampyrus	87.13	0.00e+00	835.00
IUUC-Rno-105701	Rattus norvegicus	84.21	0.00e+00	1954.00
IUUC-Smo-109107	Selaginella moellendorffii	40.11	1.00e-28	121.00
IUUC-Sit-110786	Setaria italica	41.62	6.00e-33	135.00
IUUC-Sly-110859	Solanum lycopersicum	37.62	9.00e-32	132.00
IUUC-Stu-112031	Solanum tuberosum	38.10	6.00e-32	132.00
IUUC-Sar-113242	Sorex araneus	85.27	0.00e+00	975.00
IUUC-Ssc-116094	Sus scrofa	85.44	0.00e+00	2021.00
IUUC-Tru-118308	Takifugu rubripes	62.67	0.00e+00	1337.00
IUUC-Tsy-119552	Tarsius syrichta	82.24	0.00e+00	1077.00
IUUC-Tca-121616	Theobroma cacao	38.57	3.00e-32	133.00
IUUC-Tae-124768	Triticum aestivum	41.57	4.00e-30	126.00
IUUC-Tur-126480	Triticum urartu	41.57	2.00e-30	127.00
IUUC-Tbe-127902	Tupaia belangeri	83.93	0.00e+00	867.00
IUUC-Ttr-129278	Tursiops truncatus	82.92	0.00e+00	1058.00
IUUC-Vpa-130741	Vicugna pacos	78.07	0.00e+00	742.00
IUUC-Vvi-131437	Vitis vinifera	46.10	1.00e-30	128.00
IUUC-Xtr-132247	Xenopus tropicalis	66.07	0.00e+00	1357.00
IUUC-Xma-134277	Xiphophorus maculatus	63.16	0.00e+00	1394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence