iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000009458.1	ENSONIT00000011893.1	ENSONIP00000011884.1
ENSONIG00000009458.1	ENSONIT00000011894.1	ENSONIP00000011885.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-06	29.5	385	424

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pC H+++++Cl +w    + +s  + CP Cr
   Q: 385  CKICAENDKD-VKIEPCRHLMCTSCLTAW----Q-ESEGQGCPFCR 424
           99********.******************....5.555555****8 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

PVVSHPPPAQ PRANPRSPTE LMAGNPRRGA GLIGLMKDAF QPHQQALQPH QPAVVDKKMV 60
EKCWKLMDKV VRLCQNPKVA LKNSPPYILD LLPDTYQHLR TILSRYEGKM EILGENEYFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCTTTTAC TTTGAAGATA CGGCCGGACA TCCTTGTTTA CTTTATCTGC TGGCTTGCTG 60
TTGGCTGGAT CCGCTGCTCA ACCTGTTTGT TAATCGCGCT GTGTGGCTTA TTAACGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gmo-039279	Gadus morhua	95.25	0.00e+00	881.00
IUUC-Gac-041760	Gasterosteus aculeatus	73.19	0.00e+00	1080.00
IUUC-Ola-086885	Oryzias latipes	74.39	0.00e+00	1159.00
IUUC-Pfo-096049	Poecilia formosa	76.68	0.00e+00	1242.00
IUUC-Tru-118300	Takifugu rubripes	74.86	0.00e+00	1181.00
IUUC-Tni-119861	Tetraodon nigroviridis	75.87	0.00e+00	1159.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence