iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059892

UUCD1 version

UUC-MeG-00837

Ensembl Protein ID

ENSMGAP00000007897.1

UniProt Accession

G1N6X7; G1N6X7_MELGA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000007723.1	ENSMGAT00000008685.1	ENSMGAP00000007897.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.70e-108	360.2	673	1513

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+++p +l  +++k+a++f+g
   Q: 673  TGLSNLGNTCFMNSSIQCVSNTQPLTRYFISgRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNIAPLKLRWTIAKYAPRFNG 759
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a+e++ ++n+s+++dlF+gqlksq+kc++c+++s+r++p
   Q: 760  FQQQDSQELLAFLLDGLHEDLNRVHDKPYVELKDSD--GRPDWevaaeAWENHLRRNRSIVVDLFHGQLKSQVKCKTCGHISVRFDP 844
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 845  FNFLSLPLPMDSYMHLEitvikldgttpvryglrlnmdekytglkkqlselcglkpeqillaevhssniknfpqdnqkvrlsvsgfl 931
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 932  cafeipvpgsptsasspvqsdistgssangapnvmmngdlpkptlipngmpntvvpcgternlanwtlnghvpvlsdspctgyiiav 1018
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1019 hrkmmrtelyflssqknrpslfgmplivpctvhtrkkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgns 1105
           *************************************************************************************** PP
   S: 186  ...................................................................slqdcLesftkeeelegenk 205
                                                                              +l++cL++ft+eeel ++++
   Q: 1106 cawcpwyrfcrgckiectedrasvgnayiavdwdptalhlryqtsqeriveehesveqsrraqaepiNLDSCLRAFTSEEELGEDEM 1192
           *************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................ 267
           yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f+++                        
   Q: 1193 YYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREnFDPSAFLVQrdpshfqrkqltpqideipeartl 1277
           ********************************99775..5569********************999999999999999999999998 PP
   S: 268  ....................................................................................... 267
                                                                                                  
   Q: 1278 qgdskkvdlqitystegdvnrspsslntanvmnnikaspslgrksgtscpsskssspnssprtlgrgkgrlrlpqlgknklsssken 1364
           888888888888888888888888888888888888888888888877777777777777666666666666666666666666655 PP
   S: 268  ......peekqke.......................................................................... 274
                 +                                                                                
   Q: 1365 ldgskeN-----Ctdqeqkiasdrsdtltrgqnlggsqnelytelytaqdnevtlangyiceqnaysngsingqidnhseediaddq 1446
           5555550.....055555566666666666666666666666667777777777777777777777777777777777778888888 PP
   S: 275  ......kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
                 + +Y+L+a+ +HsG +++GHYv+y+kn ++kW++++Ds+++e++ +e+ +   ++aY+lfY+++
   Q: 1447 reevcvNPIYNLYAISCHSGIMGGGHYVTYAKNPNNKWYCYNDSSCKELHPDEIDT---DSAYILFYEQQ 1513
           888888**************************************************...********985 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

VIYCSFGGIS KGLHFNNLIV GLVLLTRGKE EEKTKYIFSL FSNESGSYVV RDEMEKMLHV 60
VDGKVPESLK KCFSEGEKVN YEKFRIWLLH NKDAFTFSRW LLSGGVYVTL TDDSDTPTFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTATCTACT GTTCATTTGG AGGAATATCC AAAGGGCTGC ACTTCAATAA CTTGATAGTT 60
GGATTAGTTC TACTCACTAG AGGCAAAGAG GAGGAGAAAA CAAAATGTAA GTAATGTAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	85.45	0.00e+00	2352.00
IUUC-Apl-003272	Anas platyrhynchos	94.60	0.00e+00	2964.00
IUUC-Aca-005057	Anolis carolinensis	84.79	0.00e+00	2255.00
IUUC-Ame-010781	Astyanax mexicanus	75.14	0.00e+00	2319.00
IUUC-Bta-013502	Bos taurus	82.36	0.00e+00	2542.00
IUUC-Cel-018710	Caenorhabditis elegans	29.05	2.00e-77	283.00
IUUC-Cja-018754	Callithrix jacchus	86.47	0.00e+00	2679.00
IUUC-Cfa-020526	Canis familiaris	86.69	0.00e+00	2676.00
IUUC-Cpo-021568	Cavia porcellus	81.82	0.00e+00	2483.00
IUUC-Csa-023143	Chlorocebus sabaeus	85.82	0.00e+00	2623.00
IUUC-Cho-024603	Choloepus hoffmanni	57.12	5.00e-154	538.00
IUUC-Cin-025583	Ciona intestinalis	50.39	0.00e+00	1219.00
IUUC-Csv-026344	Ciona savignyi	46.73	0.00e+00	1125.00
IUUC-Dre-028121	Danio rerio	76.26	0.00e+00	2284.00
IUUC-Dno-029911	Dasypus novemcinctus	85.56	0.00e+00	2657.00
IUUC-Dor-030608	Dipodomys ordii	58.21	0.00e+00	1018.00
IUUC-Dme-032094	Drosophila melanogaster	44.05	1.00e-124	441.00
IUUC-Ete-032639	Echinops telfairi	83.03	0.00e+00	1409.00
IUUC-Eca-034253	Equus caballus	86.03	0.00e+00	2679.00
IUUC-Eeu-035084	Erinaceus europaeus	78.12	0.00e+00	1467.00
IUUC-Fca-035474	Felis catus	85.12	0.00e+00	2235.00
IUUC-Fal-036985	Ficedula albicollis	91.32	0.00e+00	2825.00
IUUC-Gmo-039568	Gadus morhua	74.73	0.00e+00	2234.00
IUUC-Gga-040509	Gallus gallus	95.68	0.00e+00	2993.00
IUUC-Gac-041757	Gasterosteus aculeatus	74.14	0.00e+00	2279.00
IUUC-Ggo-044956	Gorilla gorilla	83.97	0.00e+00	1601.00
IUUC-Hsa-046107	Homo sapiens	86.28	0.00e+00	2654.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	80.83	0.00e+00	1004.00
IUUC-Lch-050681	Latimeria chalumnae	78.71	0.00e+00	2392.00
IUUC-Loc-052474	Lepisosteus oculatus	77.59	0.00e+00	2397.00
IUUC-Laf-054273	Loxodonta africana	85.77	0.00e+00	2647.00
IUUC-Mcc-054718	Macaca mulatta	86.02	0.00e+00	2653.00
IUUC-Meu-056558	Macropus eugenii	71.92	0.00e+00	1287.00
IUUC-Mmr-060866	Microcebus murinus	85.36	0.00e+00	2691.00
IUUC-Mdo-062607	Monodelphis domestica	87.52	0.00e+00	2744.00
IUUC-Mmu-063797	Mus musculus	86.36	0.00e+00	2706.00
IUUC-Mpu-066121	Mustela putorius furo	86.56	0.00e+00	2700.00
IUUC-Mlu-067581	Myotis lucifugus	84.86	0.00e+00	2680.00
IUUC-Nle-069916	Nomascus leucogenys	83.97	0.00e+00	2562.00
IUUC-Opr-071073	Ochotona princeps	76.54	0.00e+00	1021.00
IUUC-Ont-071310	Oreochromis niloticus	81.33	0.00e+00	2076.00
IUUC-Oan-073356	Ornithorhynchus anatinus	85.98	0.00e+00	2680.00
IUUC-Ocu-074216	Oryctolagus cuniculus	86.40	0.00e+00	2664.00
IUUC-Ola-087434	Oryzias latipes	73.31	0.00e+00	2213.00
IUUC-Oga-089034	Otolemur garnettii	85.91	0.00e+00	2688.00
IUUC-Oar-090369	Ovis aries	86.29	0.00e+00	2719.00
IUUC-Ptr-090605	Pan troglodytes	86.40	0.00e+00	2659.00
IUUC-Pan-092381	Papio anubis	85.92	0.00e+00	2647.00
IUUC-Psi-093819	Pelodiscus sinensis	90.98	0.00e+00	2857.00
IUUC-Pma-094480	Petromyzon marinus	63.49	0.00e+00	1407.00
IUUC-Pfo-096561	Poecilia formosa	80.44	0.00e+00	2029.00
IUUC-Pab-097643	Pongo abelii	86.21	0.00e+00	2649.00
IUUC-Pca-100944	Procavia capensis	70.10	0.00e+00	934.00
IUUC-Pva-102732	Pteropus vampyrus	76.53	0.00e+00	2307.00
IUUC-Rno-105113	Rattus norvegicus	86.36	0.00e+00	2682.00
IUUC-Sha-107608	Sarcophilus harrisii	75.69	1.00e-165	575.00
IUUC-Sar-113201	Sorex araneus	74.91	0.00e+00	1536.00
IUUC-Ssc-115469	Sus scrofa	75.19	4.00e-153	533.00
IUUC-Tgu-117322	Taeniopygia guttata	92.40	0.00e+00	2888.00
IUUC-Tru-118705	Takifugu rubripes	69.40	0.00e+00	683.00
IUUC-Tsy-119433	Tarsius syrichta	74.39	0.00e+00	1945.00
IUUC-Tni-120631	Tetraodon nigroviridis	80.55	0.00e+00	2080.00
IUUC-Tbe-127553	Tupaia belangeri	90.79	2.00e-169	590.00
IUUC-Ttr-128260	Tursiops truncatus	85.29	0.00e+00	2677.00
IUUC-Vpa-130479	Vicugna pacos	81.27	0.00e+00	2472.00
IUUC-Xtr-132686	Xenopus tropicalis	82.95	0.00e+00	2530.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence