iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116304

Ensembl Protein ID

ENSSSCP00000024065.1

UniProt Accession

I3LJ08; I3LJ08_PIG

Genbank Protein ID

ENSSSCP00000024065

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU570907

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000021721.1	ENSSSCT00000029246.1	ENSSSCP00000024065.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.40e-88	295.2	132	461

Active Site

Position(s)	Description	Evidence
430	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 7    krlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.....ehlklFeflGrllgkalqdgrlldl 90
           ++++v+fvgE++ d+gG  +e +a++++elqn  ++l+  ++n++ +   n+d +l +p      h+++F+flG+llg+a+++g +l l
   Q: 132  RVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLFSPaarapVHTNMFRFLGVLLGIAIRTGSPLSL 220
           4566****************************************************99999999************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
           +l+++++k+l g +l++ dl+evd++++  l++i++n+ ++ e +++ l f+     +++++ +++  +++ +++t +N+ eYv+l ++
   Q: 221  NLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFT-----VPSASGQDIQLSSKYTHITLDNRAEYVRLAIN 304
           *************************************9999999999***99.....788999999*********************** PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           yrl+e ++eqv+a+reG+ +v+p  llslFt  ele+++cG+++i ++ lk+ ++ykg ++++ + iqwFwev+e+fs++er+ fL+Fv
   Q: 305  YRLHE-FDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKG-VEPSASLIQWFWEVMESFSNTERSLFLRFV 391
           *****.**************************************************77.****************************** PP
   S: 269  TgssrlPlgGfaelkprlfvirk....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           +g+ rlP + +a+++ r fvi+     +  d+ lP+s TCf++LkLP+Ys k++l+ekL yAi+ +k++++
   Q: 392  WGRTRLP-RTIADFRGRDFVIQVldkyNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDT 461
           *******.8*************999988888***********************************99875 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MEYNHLQEIP IIALRNRLLL LHHISELFCP CIPMFDLEGS LDETGLGPSV GFDTLRGILI 60
SQGKEAAFRK VVQATMVRDR QHGPVVELNR IQVKRSRSKG GLAGPDGTKS VFGQMCAKMS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGATTACAGA TGTCTGGGTC ATCATGAGGT TAACATTCAT ACAGATGACT GCCAGCACCC 60
AACTGGACGG TAGTGAAGAC TGTATATGGG AAGACGGTGG TGGCTGTGCG TTCATTGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cin-025709	Ciona intestinalis	66.46	0.00e+00	660.00
IUUC-Csv-026336	Ciona savignyi	67.50	0.00e+00	669.00
IUUC-Dme-032171	Drosophila melanogaster	67.38	0.00e+00	660.00
IUUC-Gmo-038739	Gadus morhua	87.68	0.00e+00	726.00
IUUC-Gac-041879	Gasterosteus aculeatus	89.13	0.00e+00	738.00
IUUC-Lch-049808	Latimeria chalumnae	94.84	0.00e+00	936.00
IUUC-Meu-056660	Macropus eugenii	96.81	0.00e+00	954.00
IUUC-Oan-072721	Ornithorhynchus anatinus	94.44	0.00e+00	927.00
IUUC-Ola-087346	Oryzias latipes	93.33	0.00e+00	911.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence