iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062348

UUCD1 version

UUC-MoD-01024

Ensembl Protein ID

ENSMODP00000018605.2

UniProt Accession

F6YKS8; F6YKS8_MONDO

Protein Name

Uncharacterized protein

Gene Name

UBE2E1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000014876.3	ENSMODT00000018940.3	ENSMODP00000018605.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.70e-50	168.4	38	173

Active Site

Position(s)	Description	Evidence
118	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++++ dpp+++sa+p+ + +++ew+ +ilGp++++Ye gvF l+i+f+++YPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 38   RIQKELADITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYESGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 123
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 124  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQ 173
           *********************************************99985 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

SSIHSFIHSV SQNLNLAKKK ENIIFTKRKK FPATLRLRIQ KELADITLDP PPNCSAGPKG 60
DNIYEWRSTI LGPPGSVYES GVFFLDITFT PEYPFKPPKV TFRTRIYHCN INSQGVICLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCATCCATTC ATTCATTCAT CCATTCAGTC AGTCAAAATC TTAACTTAGC CAAGAAAAAA 60
GAAAACATTA TCTTCTAGAC TAAAAGAAAG AAATTTCCTG CAAGAGGTCA CAAAAATAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0042296--F:ISG15 transferase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0033523--P:histone H2B ubiquitination
GO:0010390--P:histone monoubiquitination
GO:0032020--P:ISG15-protein conjugation
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dno-029441	Dasypus novemcinctus	99.21	3.00e-73	266.00
IUUC-Dor-030450	Dipodomys ordii	99.09	2.00e-62	229.00
IUUC-Eca-033613	Equus caballus	99.30	1.00e-83	301.00
IUUC-Itr-048197	Ictidomys tridecemlineatus	99.21	3.00e-73	266.00
IUUC-Meu-056590	Macropus eugenii	99.30	6.00e-83	298.00
IUUC-Oan-073006	Ornithorhynchus anatinus	99.21	5.00e-73	265.00
IUUC-Ola-086636	Oryzias latipes	95.80	4.00e-81	293.00
IUUC-Pma-094642	Petromyzon marinus	94.44	7.00e-70	254.00
IUUC-Pfo-096966	Poecilia formosa	95.80	5.00e-81	293.00
IUUC-Sha-106897	Sarcophilus harrisii	98.61	5.00e-84	302.00
IUUC-Ssc-116298	Sus scrofa	99.30	1.00e-83	301.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence