iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074224

Ensembl Protein ID

ENSOCUP00000010018.3

UniProt Accession

G1T1P7; G1T1P7_RABIT

Genbank Protein ID

ENSOCUP00000010018

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02028688

Gene Name

AHI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000011645.3	ENSOCUT00000011648.3	ENSOCUP00000010018.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-19	68.5	635	665
UBD/SH3	6.40e-14	51.7	1047	1099

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH + +++l++ +d ++++++s Dgt ++W 
   Q: 635  GHLNIIYDLCWsTDdRYILTSSSDGTARIWK 665
           79999*******666***************7 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v +lydy+a+ +deLt+++Gd+++v    + +e+W++g +  +g+ G fP+n v+
   Q: 1047 TVVALYDYTANRSDELTIHRGDIIRVF--FKDNEDWWYG-SIGKGQDGYFPANHVA 1099
           689***********************9..8999******.799**********996 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MPAVESEAKV KTKVRFEELL KTHNDLIRER KRLKKKLAKS KENISADAVR SNLQNIKESE 60
SGDVKATNTD NPEKGMRVSK NKLRNTQSAA ESPHDDASVE EDKQGKPNRK AGKTAPQVTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTGTCAACC TGGCGCTGAA TGTTGAACCT GTGAAGTGCC TTCTTAATGA CACCCAGAAA 60
AGGTGACGGA TACGTTACGT TTCTAAGAAA AGAGTCAAAT TCTGTTAGAG GCGTTTTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR023302--Pept_S9A_N
IPR001452--SH3_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50002--SH3
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00018--SH3_1
PF00400--WD40

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3
SM00320--WD40

Gene Ontology

GO:0005912--C:adherens junction
GO:0005911--C:cell-cell junction
GO:0005814--C:centriole
GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0005929--C:cilium
GO:0097730--C:non-motile cilium
GO:0034613--P:cellular protein localization
GO:0007417--P:central nervous system development
GO:0060271--P:cilium assembly
GO:0035844--P:cloaca development
GO:0001947--P:heart looping
GO:0030902--P:hindbrain development
GO:0070121--P:Kupffer's vesicle development
GO:0070986--P:left/right axis specification
GO:0001738--P:morphogenesis of a polarized epithelium
GO:0043066--P:negative regulation of apoptotic process
GO:0071599--P:otic vesicle development
GO:0035845--P:photoreceptor cell outer segment organization
GO:0030862--P:positive regulation of polarized epithelial cell differentiation
GO:0002092--P:positive regulation of receptor internalization
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0039023--P:pronephric duct morphogenesis
GO:0039008--P:pronephric nephron tubule morphogenesis
GO:0050795--P:regulation of behavior
GO:0010842--P:retina layer formation
GO:0065001--P:specification of axis polarity
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016192--P:vesicle-mediated transport

KEGG

ocu:100339239

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001943	Ailuropoda melanoleuca	81.09	0.00e+00	1650.00
IUUC-Apl-004057	Anas platyrhynchos	50.13	0.00e+00	1059.00
IUUC-Aca-004306	Anolis carolinensis	48.09	0.00e+00	956.00
IUUC-Ame-010981	Astyanax mexicanus	48.63	0.00e+00	842.00
IUUC-Bta-013129	Bos taurus	82.67	0.00e+00	1841.00
IUUC-Cja-018979	Callithrix jacchus	80.42	0.00e+00	1612.00
IUUC-Cfa-020121	Canis familiaris	82.77	0.00e+00	1892.00
IUUC-Cpo-022219	Cavia porcellus	81.71	0.00e+00	1372.00
IUUC-Csa-023991	Chlorocebus sabaeus	84.09	0.00e+00	1974.00
IUUC-Cho-024782	Choloepus hoffmanni	80.45	0.00e+00	992.00
IUUC-Cin-025149	Ciona intestinalis	38.80	5.00e-167	581.00
IUUC-Csv-026188	Ciona savignyi	38.37	2.00e-123	435.00
IUUC-Dre-028737	Danio rerio	51.03	0.00e+00	848.00
IUUC-Dno-029756	Dasypus novemcinctus	80.86	0.00e+00	1757.00
IUUC-Dor-030821	Dipodomys ordii	73.64	0.00e+00	1571.00
IUUC-Ete-032237	Echinops telfairi	74.30	0.00e+00	1586.00
IUUC-Eca-033491	Equus caballus	82.45	0.00e+00	1913.00
IUUC-Eeu-034812	Erinaceus europaeus	71.18	0.00e+00	931.00
IUUC-Fca-035868	Felis catus	82.45	0.00e+00	1813.00
IUUC-Fal-037571	Ficedula albicollis	55.26	0.00e+00	810.00
IUUC-Gmo-039358	Gadus morhua	49.62	0.00e+00	789.00
IUUC-Gga-040233	Gallus gallus	52.89	0.00e+00	991.00
IUUC-Gac-041744	Gasterosteus aculeatus	48.60	0.00e+00	791.00
IUUC-Ggo-044766	Gorilla gorilla	84.26	0.00e+00	1996.00
IUUC-Hsa-046660	Homo sapiens	84.09	0.00e+00	1995.00
IUUC-Itr-048282	Ictidomys tridecemlineatus	85.49	0.00e+00	1994.00
IUUC-Loc-052658	Lepisosteus oculatus	48.28	0.00e+00	914.00
IUUC-Laf-053564	Loxodonta africana	86.10	0.00e+00	1473.00
IUUC-Mcc-055480	Macaca mulatta	84.34	0.00e+00	1989.00
IUUC-Meu-056362	Macropus eugenii	58.73	0.00e+00	814.00
IUUC-Mga-060033	Meleagris gallopavo	51.25	0.00e+00	1081.00
IUUC-Mmr-061075	Microcebus murinus	84.75	0.00e+00	1985.00
IUUC-Mdo-062818	Monodelphis domestica	55.28	0.00e+00	1199.00
IUUC-Mmu-063987	Mus musculus	80.24	0.00e+00	1655.00
IUUC-Mpu-066242	Mustela putorius furo	79.31	0.00e+00	1783.00
IUUC-Mlu-067123	Myotis lucifugus	76.58	0.00e+00	1673.00
IUUC-Nle-069793	Nomascus leucogenys	84.42	0.00e+00	2003.00
IUUC-Opr-071110	Ochotona princeps	81.48	0.00e+00	951.00
IUUC-Ont-072179	Oreochromis niloticus	47.50	0.00e+00	832.00
IUUC-Oan-073201	Ornithorhynchus anatinus	63.16	6.00e-135	473.00
IUUC-Ola-086818	Oryzias latipes	53.24	3.00e-73	267.00
IUUC-Oga-088338	Otolemur garnettii	85.93	0.00e+00	1824.00
IUUC-Oar-089247	Ovis aries	79.81	0.00e+00	1874.00
IUUC-Ptr-090830	Pan troglodytes	85.13	0.00e+00	1953.00
IUUC-Pan-092469	Papio anubis	84.84	0.00e+00	2008.00
IUUC-Psi-093183	Pelodiscus sinensis	52.48	0.00e+00	1063.00
IUUC-Pma-094415	Petromyzon marinus	46.37	2.00e-158	552.00
IUUC-Pfo-096577	Poecilia formosa	45.40	0.00e+00	807.00
IUUC-Pab-098236	Pongo abelii	83.52	0.00e+00	1703.00
IUUC-Pca-100560	Procavia capensis	68.49	0.00e+00	1481.00
IUUC-Pva-102565	Pteropus vampyrus	77.43	0.00e+00	1342.00
IUUC-Rno-104881	Rattus norvegicus	80.07	0.00e+00	1681.00
IUUC-Sha-106577	Sarcophilus harrisii	65.23	5.00e-163	566.00
IUUC-Sar-113265	Sorex araneus	69.45	0.00e+00	1491.00
IUUC-Ssc-116174	Sus scrofa	81.29	0.00e+00	1857.00
IUUC-Tgu-116618	Taeniopygia guttata	50.00	0.00e+00	893.00
IUUC-Tru-117761	Takifugu rubripes	41.80	0.00e+00	681.00
IUUC-Tsy-119557	Tarsius syrichta	82.67	0.00e+00	991.00
IUUC-Tni-119782	Tetraodon nigroviridis	49.87	0.00e+00	805.00
IUUC-Tbe-127529	Tupaia belangeri	71.28	8.00e-150	525.00
IUUC-Ttr-128444	Tursiops truncatus	79.80	0.00e+00	1823.00
IUUC-Vpa-130337	Vicugna pacos	74.49	0.00e+00	1641.00
IUUC-Xtr-132055	Xenopus tropicalis	56.95	0.00e+00	736.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence