iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133625

Ensembl Protein ID

ENSXMAP00000009747.1

UniProt Accession

M4A5K3; M4A5K3_XIPMA

Genbank Protein ID

ENSXMAP00000009747

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01004807

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000009721.1	ENSXMAT00000009761.1	ENSXMAP00000009747.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.50e-77	259.9	445	933

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNS++Q+L++ +++r+ +l+    +ln +      ++++k lq lf+ l ++++ a++pr++l++ +   + f+  +q
   Q: 445  TGLINLGNTCYMNSIIQTLFMATDFRRHVLS---LHLNGS------NTVMKRLQLLFAFLAHTQRAAYAPRNFLEVSR--PPWFNVGSQ 522
           7******************************...666665......58***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk................eknkpkeeeeeedkselsde....................aeekkkkknksli 142
           qD++E+l+fll++l+ee k                                    +                    ae++  + +++li
   Q: 523  QDCSEYLRFLLERLHEEEKTlhvlqsakptvaslvdP------------------IsrdpispttsedckdchlveAENRCANDGRTLI 593
           ******************6666654444444333330..................1333345666666667777778899999999*** PP
   S: 143  sdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.............................................s 186
           +++F+g+l + i+c +c+++s++eepf+dlsl++  +++++ +                                             s
   Q: 594  ERMFGGKLITGIRCMQCNSISEKEEPFTDLSLAFCPSSSSQGSpkserpteegkvlcqgsvnggseapessnlatnvqyepvtnepplS 682
           ***********************************99987666999******************************************* PP
   S: 187  lqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts........ 267
           + d+ + f ++e l+++n+y+cekc ++q+ae+++k+ + Pe+Lil L Rfs++ + + r+ki ++v +p  L l  + +         
   Q: 683  VPDLVNYFLAPEILDEDNAYFCEKCVSLQRAERTMKVVSAPEYLILTLLRFSYDAKSHIRKKILDNVIIPPALRLPVHASAtpvqwssa 771
           **********************************************************************9999987666678888888 PP
   S: 268  ..............................peekqke..................kkkYeLiavvvHsG.slssGHYvayvkn...... 301
                                         +     +                  ++ Y L++vvvHsG s++sGHY++y +n      
   Q: 772  sssplqvdspessenlakklkpsqgeeeeeR-----KlrldeaekmtrgretsvqSVPYMLSSVVVHSGvSSESGHYYSYGRNingadg 855
           8888888888877777777776665555550.....0555556666666666666********************************** PP
   S: 302  .....................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                                e ++Wllf+Ds+Vt ++ ++v++ t+    +taYvl+Y+++
   Q: 856  tqhpagfssvkqdlasdqaacslckseqgdslpnvglEARDWLLFNDSRVTYTSLQSVQNITNrfpkDTAYVLMYRKQ 933
           *********************99999999888888877888*******************999************986 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MDKILEGLIS SDHSVPVKRA IVKKVVEAAE NDVTQEQCRA LFTLTTRLIL LGDDAFQKQI 60
GLQVLEAYAR YHRPEFELFF CKDFVLCLLQ QGYGQLEHRD AAIIDYIHCC LRLLISCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAGCAGA GAAGCACCCC TGATGCAAAA AGAACTAATT ATCTATAAAT AGACTAAGTA 60
TGTCCATATA AAGACAAAGT AAATCTAAAG CGTTCTTAGT TGCTATATAG AAATACCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

xma:102218346

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	62.01	0.00e+00	1166.00
IUUC-Apl-003435	Anas platyrhynchos	60.60	0.00e+00	974.00
IUUC-Aca-004556	Anolis carolinensis	57.22	0.00e+00	1006.00
IUUC-Ame-010616	Astyanax mexicanus	69.05	0.00e+00	1339.00
IUUC-Bta-013544	Bos taurus	62.50	0.00e+00	1170.00
IUUC-Cja-018745	Callithrix jacchus	60.65	0.00e+00	1169.00
IUUC-Cfa-020434	Canis familiaris	61.50	0.00e+00	1152.00
IUUC-Cpo-021666	Cavia porcellus	61.14	0.00e+00	1133.00
IUUC-Csa-023965	Chlorocebus sabaeus	62.13	0.00e+00	1203.00
IUUC-Cho-024809	Choloepus hoffmanni	53.48	0.00e+00	721.00
IUUC-Cin-025604	Ciona intestinalis	30.58	2.00e-43	169.00
IUUC-Csv-026333	Ciona savignyi	40.88	2.00e-30	125.00
IUUC-Dre-028338	Danio rerio	68.24	0.00e+00	1348.00
IUUC-Dno-029372	Dasypus novemcinctus	61.47	0.00e+00	1186.00
IUUC-Dor-030752	Dipodomys ordii	57.43	0.00e+00	728.00
IUUC-Dme-031871	Drosophila melanogaster	29.83	1.00e-60	228.00
IUUC-Ete-032588	Echinops telfairi	52.64	0.00e+00	673.00
IUUC-Eca-034416	Equus caballus	62.35	0.00e+00	1190.00
IUUC-Eeu-035132	Erinaceus europaeus	49.53	0.00e+00	828.00
IUUC-Fca-036137	Felis catus	62.07	0.00e+00	1191.00
IUUC-Fal-037297	Ficedula albicollis	60.22	0.00e+00	1135.00
IUUC-Gmo-038727	Gadus morhua	79.40	0.00e+00	1211.00
IUUC-Gga-041091	Gallus gallus	60.84	0.00e+00	1102.00
IUUC-Gac-042082	Gasterosteus aculeatus	80.77	0.00e+00	1509.00
IUUC-Ggo-045376	Gorilla gorilla	58.47	0.00e+00	1080.00
IUUC-Hsa-046444	Homo sapiens	62.33	0.00e+00	1201.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	62.00	0.00e+00	1193.00
IUUC-Lch-050500	Latimeria chalumnae	58.56	0.00e+00	1100.00
IUUC-Loc-052625	Lepisosteus oculatus	67.88	0.00e+00	1362.00
IUUC-Laf-053689	Loxodonta africana	62.20	0.00e+00	1181.00
IUUC-Mcc-055286	Macaca mulatta	62.27	0.00e+00	1192.00
IUUC-Meu-056906	Macropus eugenii	48.81	0.00e+00	628.00
IUUC-Mga-059905	Meleagris gallopavo	60.13	0.00e+00	946.00
IUUC-Mmr-061397	Microcebus murinus	62.65	0.00e+00	1170.00
IUUC-Mdo-062833	Monodelphis domestica	62.19	0.00e+00	1224.00
IUUC-Mmu-063157	Mus musculus	61.18	0.00e+00	1162.00
IUUC-Mpu-066434	Mustela putorius furo	62.37	0.00e+00	1200.00
IUUC-Mlu-068178	Myotis lucifugus	61.76	0.00e+00	1144.00
IUUC-Nle-070153	Nomascus leucogenys	61.92	0.00e+00	1159.00
IUUC-Opr-070454	Ochotona princeps	44.29	1.00e-68	254.00
IUUC-Ont-072330	Oreochromis niloticus	80.67	0.00e+00	1571.00
IUUC-Oan-072709	Ornithorhynchus anatinus	58.88	0.00e+00	884.00
IUUC-Ocu-074832	Oryctolagus cuniculus	63.27	0.00e+00	1184.00
IUUC-Ola-087003	Oryzias latipes	70.98	1.00e-63	235.00
IUUC-Oga-088517	Otolemur garnettii	61.41	0.00e+00	1161.00
IUUC-Oar-089472	Ovis aries	60.33	0.00e+00	1094.00
IUUC-Ptr-090996	Pan troglodytes	62.45	0.00e+00	1204.00
IUUC-Pan-091837	Papio anubis	61.25	0.00e+00	1159.00
IUUC-Psi-093236	Pelodiscus sinensis	60.07	0.00e+00	856.00
IUUC-Pma-094349	Petromyzon marinus	52.50	0.00e+00	926.00
IUUC-Pfo-097193	Poecilia formosa	96.61	0.00e+00	1858.00
IUUC-Pab-098710	Pongo abelii	62.22	0.00e+00	1221.00
IUUC-Pca-100794	Procavia capensis	54.29	0.00e+00	983.00
IUUC-Pva-102722	Pteropus vampyrus	62.10	0.00e+00	1189.00
IUUC-Rno-105743	Rattus norvegicus	60.48	0.00e+00	1150.00
IUUC-Sha-106563	Sarcophilus harrisii	60.70	0.00e+00	963.00
IUUC-Sar-113533	Sorex araneus	56.44	0.00e+00	1004.00
IUUC-Ssc-116259	Sus scrofa	77.45	0.00e+00	801.00
IUUC-Tgu-117475	Taeniopygia guttata	59.71	0.00e+00	1016.00
IUUC-Tru-118623	Takifugu rubripes	75.02	0.00e+00	1431.00
IUUC-Tsy-119250	Tarsius syrichta	59.48	0.00e+00	855.00
IUUC-Tni-120441	Tetraodon nigroviridis	71.91	0.00e+00	1356.00
IUUC-Tbe-127936	Tupaia belangeri	52.64	0.00e+00	889.00
IUUC-Ttr-128483	Tursiops truncatus	53.35	0.00e+00	825.00
IUUC-Vpa-130303	Vicugna pacos	77.34	0.00e+00	851.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence