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Tag Content
UUCD2 ID IUUC-Bta-012432
UUCD1 version UUC-BoT-00078
Ensembl Protein ID ENSBTAP00000027702.4
UniProt Accession A6QLW1; A6QLW1_BOVIN
Genbank Protein ID AAI48106.1
Protein Name PIK3R4 protein
Genbank Nucleotide ID DAAA02003664
Gene Name PIK3R4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000020787.4 ENSBTAT00000027702.4 ENSBTAP00000027702.4
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.20e-17 63.4 992 1021
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H++ v+ ++  ++  l++++s+Dgt+k+W+
   Q: 992  HKSAVNRIRVsDEhSLFATCSNDGTVKIWN 1021
           9999999999544788*************9 PP
   
Organism Bos taurus
Protein Sequence
(Fasta)
MGNQLAGIAP SQILSVESYF SDIHDFEYDK SLGSTRFFKV ARAKHREGLV VVKVFAIQDP 60
TLPLTSYKQE LEELKIRLHS AQNCLPFQKA AEKASEKAAM LFRQYVRDNL YDRISTRPFL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-012432|E3,WD_repeat|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCACAGGAA GTTGGGTCCG AGCCGGCGGC TTCTCTTGGG AGCTCGGCCC GCGGGGCGTC 60
GGCCGGCCGC CGCCGGAGAG GCTGCGTTTC CCCGGGCCCC GGAAGCCGGC CCGTCCTCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-012432|E3,WD_repeat|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021133--HEAT_type_2
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50077--HEAT_REPEAT
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00069--Pkinase
PF00400--WD40
SMART

SM00220--S_TKc
SM00320--WD40
Gene Ontology

GO:0005930--C:axoneme
GO:0005770--C:late endosome
GO:0015630--C:microtubule cytoskeleton
GO:0005643--C:nuclear pore
GO:0071561--C:nucleus-vacuole junction
GO:0034271--C:phosphatidylinositol 3-kinase complex, class III, type I
GO:0034272--C:phosphatidylinositol 3-kinase complex, class III, type II
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0042149--P:cellular response to glucose starvation
GO:0045324--P:late endosome to vacuole transport
GO:0016236--P:macroautophagy
GO:0030242--P:pexophagy
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0006468--P:protein phosphorylation
GO:0006623--P:protein targeting to vacuole
GO:0032801--P:receptor catabolic process
GO:0032465--P:regulation of cytokinesis
KEGG bta:507414
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000213 Aegilops tauschii 31.87 4.00e-44 174.00
IUUC-Aml-001659 Ailuropoda melanoleuca 97.13 0.00e+00 2680.00
IUUC-Atr-002968 Amborella trichopoda 39.10 8.00e-45 176.00
IUUC-Apl-003418 Anas platyrhynchos 90.32 0.00e+00 2573.00
IUUC-Aca-004344 Anolis carolinensis 89.67 0.00e+00 2288.00
IUUC-Aly-006107 Arabidopsis lyrata 46.06 9.00e-69 256.00
IUUC-Ath-007260 Arabidopsis thaliana 46.36 2.00e-69 258.00
IUUC-Ago-007721 Ashbya gossypii 24.38 2.00e-56 215.00
IUUC-Acl-008378 Aspergillus clavatus 37.06 1.00e-146 514.00
IUUC-Afl-008632 Aspergillus flavus 35.86 1.00e-140 494.00
IUUC-Afu-009020 Aspergillus fumigatus 36.22 3.00e-141 496.00
IUUC-Ani-009204 Aspergillus nidulans 35.63 2.00e-131 464.00
IUUC-Ang-009811 Aspergillus niger 35.30 3.00e-138 487.00
IUUC-Aor-010168 Aspergillus oryzae 35.86 1.00e-140 494.00
IUUC-Ate-010556 Aspergillus terreus 35.36 2.00e-138 487.00
IUUC-Ame-011955 Astyanax mexicanus 81.11 0.00e+00 1823.00
IUUC-Bgr-012050 Blumeria graminis 36.46 1.00e-138 488.00
IUUC-Bci-013846 Botrytis cinerea 34.60 3.00e-142 499.00
IUUC-Bdi-015072 Brachypodium distachyon 40.92 3.00e-65 244.00
IUUC-Bol-015314 Brassica oleracea 26.94 2.00e-90 328.00
IUUC-Bra-017476 Brassica rapa 46.67 2.00e-69 258.00
IUUC-Cel-018550 Caenorhabditis elegans 31.60 1.00e-82 301.00
IUUC-Cja-019538 Callithrix jacchus 95.95 0.00e+00 2705.00
IUUC-Cfa-020483 Canis familiaris 96.83 0.00e+00 2685.00
IUUC-Cpo-021392 Cavia porcellus 95.88 0.00e+00 2690.00
IUUC-Csa-024112 Chlorocebus sabaeus 96.54 0.00e+00 2717.00
IUUC-Cho-025015 Choloepus hoffmanni 89.96 0.00e+00 944.00
IUUC-Cin-025209 Ciona intestinalis 41.60 0.00e+00 1077.00
IUUC-Csv-026334 Ciona savignyi 42.25 0.00e+00 892.00
IUUC-Cgl-026447 Colletotrichum gloeosporioides 35.80 3.00e-143 503.00
IUUC-Cne-026999 Cryptococcus neoformans 39.12 2.00e-113 404.00
IUUC-Dre-028662 Danio rerio 80.93 0.00e+00 2300.00
IUUC-Dno-029545 Dasypus novemcinctus 94.85 0.00e+00 2640.00
IUUC-Dor-030941 Dipodomys ordii 70.35 0.00e+00 649.00
IUUC-Dse-031455 Dothistroma septosporum 36.34 4.00e-135 476.00
IUUC-Dme-031726 Drosophila melanogaster 40.37 0.00e+00 989.00
IUUC-Ete-033147 Echinops telfairi 94.12 0.00e+00 1012.00
IUUC-Eca-034025 Equus caballus 97.20 0.00e+00 2728.00
IUUC-Eeu-034480 Erinaceus europaeus 90.64 0.00e+00 1524.00
IUUC-Fca-035741 Felis catus 96.54 0.00e+00 2690.00
IUUC-Fal-037666 Ficedula albicollis 89.58 0.00e+00 2549.00
IUUC-Fox-037818 Fusarium oxysporum 33.98 5.00e-126 446.00
IUUC-Fso-038086 Fusarium solani 34.81 2.00e-130 461.00
IUUC-Gmo-038804 Gadus morhua 80.05 0.00e+00 736.00
IUUC-Ggr-039800 Gaeumannomyces graminis 35.94 1.00e-133 471.00
IUUC-Gga-041251 Gallus gallus 89.53 0.00e+00 2013.00
IUUC-Gac-042376 Gasterosteus aculeatus 78.95 0.00e+00 2230.00
IUUC-Gma-044095 Glycine max 45.30 3.00e-71 264.00
IUUC-Ggo-044506 Gorilla gorilla 96.03 0.00e+00 2700.00
IUUC-Hsa-045871 Homo sapiens 96.61 0.00e+00 2715.00
IUUC-Hvu-047648 Hordeum vulgare 31.01 9.00e-46 179.00
IUUC-Itr-048082 Ictidomys tridecemlineatus 98.34 0.00e+00 1204.00
IUUC-Kpa-049390 Komagataella pastoris 32.84 3.00e-125 443.00
IUUC-Lch-050284 Latimeria chalumnae 84.71 0.00e+00 2322.00
IUUC-Lpe-050880 Leersia perrieri 40.91 1.00e-62 235.00
IUUC-Loc-052815 Lepisosteus oculatus 81.40 0.00e+00 2305.00
IUUC-Lma-053324 Leptosphaeria maculans 32.11 2.00e-172 601.00
IUUC-Laf-054204 Loxodonta africana 84.67 0.00e+00 2302.00
IUUC-Mcc-054612 Macaca mulatta 96.61 0.00e+00 2719.00
IUUC-Meu-056227 Macropus eugenii 85.71 0.00e+00 847.00
IUUC-Mor-057094 Magnaporthe oryzae 36.51 6.00e-135 476.00
IUUC-Mtr-058550 Medicago truncatula 43.37 2.00e-70 261.00
IUUC-Mla-058893 Melampsora laricipopulina 34.56 4.00e-127 449.00
IUUC-Mga-059474 Meleagris gallopavo 89.45 0.00e+00 2420.00
IUUC-Mvi-060227 Microbotryum violaceum 43.66 6.00e-81 296.00
IUUC-Mmr-061543 Microcebus murinus 89.40 0.00e+00 2426.00
IUUC-Mdo-062129 Monodelphis domestica 92.84 0.00e+00 2524.00
IUUC-Mmu-064381 Mus musculus 94.11 0.00e+00 2652.00
IUUC-Mac-064455 Musa acuminata 38.06 5.00e-122 432.00
IUUC-Mpu-066151 Mustela putorius furo 98.34 0.00e+00 983.00
IUUC-Mlu-067824 Myotis lucifugus 96.91 0.00e+00 2724.00
IUUC-Nfi-068241 Neosartorya fischeri 37.32 2.00e-143 504.00
IUUC-Ncr-068964 Neurospora crassa 36.44 4.00e-140 493.00
IUUC-Nle-069152 Nomascus leucogenys 96.69 0.00e+00 2717.00
IUUC-Opr-070870 Ochotona princeps 85.43 0.00e+00 1428.00
IUUC-Ont-071293 Oreochromis niloticus 80.55 0.00e+00 2282.00
IUUC-Oan-072852 Ornithorhynchus anatinus 86.81 0.00e+00 2410.00
IUUC-Ocu-074727 Oryctolagus cuniculus 96.91 0.00e+00 2687.00
IUUC-Oba-075932 Oryza barthii 37.77 8.00e-63 236.00
IUUC-Obr-076424 Oryza brachyantha 47.76 7.00e-61 229.00
IUUC-Ogl-077491 Oryza glaberrima 37.77 8.00e-63 236.00
IUUC-Ogu-078933 Oryza glumaepatula 35.45 2.00e-110 394.00
IUUC-Oin-079604 Oryza indica 41.71 2.00e-68 254.00
IUUC-Olo-080850 Oryza longistaminata 35.80 5.00e-116 412.00
IUUC-Ome-081860 Oryza meridionalis 41.71 2.00e-68 254.00
IUUC-Oni-082895 Oryza nivara 37.77 2.00e-62 235.00
IUUC-Opu-083741 Oryza punctata 41.71 2.00e-67 251.00
IUUC-Oru-084616 Oryza rufipogon 37.50 4.00e-62 234.00
IUUC-Osa-085941 Oryza sativa 27.78 3.00e-35 142.00
IUUC-Ola-087357 Oryzias latipes 84.94 3.00e-156 544.00
IUUC-Olu-087659 Ostreococcus lucimarinus 30.86 2.00e-87 317.00
IUUC-Oga-088555 Otolemur garnettii 96.47 0.00e+00 2694.00
IUUC-Oar-089304 Ovis aries 96.10 0.00e+00 1343.00
IUUC-Ptr-091140 Pan troglodytes 96.69 0.00e+00 2717.00
IUUC-Pan-092413 Papio anubis 96.27 0.00e+00 2608.00
IUUC-Psi-093210 Pelodiscus sinensis 90.30 0.00e+00 2572.00
IUUC-Pma-094674 Petromyzon marinus 57.32 0.00e+00 741.00
IUUC-Pno-094969 Phaeosphaeria nodorum 31.78 2.00e-146 514.00
IUUC-Ppa-096017 Physcomitrella patens 45.56 2.00e-74 274.00
IUUC-Pfo-096077 Poecilia formosa 80.04 0.00e+00 2229.00
IUUC-Pab-098269 Pongo abelii 95.80 0.00e+00 2698.00
IUUC-Pop-100052 Populus trichocarpa 43.67 2.00e-62 234.00
IUUC-Pca-100377 Procavia capensis 90.48 0.00e+00 2426.00
IUUC-Ppe-101445 Prunus persica 46.08 7.00e-71 263.00
IUUC-Pva-102198 Pteropus vampyrus 97.79 0.00e+00 1799.00
IUUC-Pgr-103544 Puccinia graminis 46.54 6.00e-78 286.00
IUUC-Ptt-103964 Puccinia triticina 46.23 7.00e-75 276.00
IUUC-Pte-104196 Pyrenophora teres 37.18 6.00e-138 485.00
IUUC-Pyt-104544 Pyrenophora triticirepentis 37.74 5.00e-137 482.00
IUUC-Rno-105256 Rattus norvegicus 94.33 0.00e+00 2658.00
IUUC-Sce-106295 Saccharomyces cerevisiae 33.00 3.00e-111 396.00
IUUC-Sha-107597 Sarcophilus harrisii 92.08 0.00e+00 2553.00
IUUC-Sja-107781 Schizosaccharomyces japonicus 32.82 1.00e-98 355.00
IUUC-Spo-108031 Schizosaccharomyces pombe 43.54 2.00e-71 265.00
IUUC-Ssl-108579 Sclerotinia sclerotiorum 35.64 2.00e-135 477.00
IUUC-Smo-108679 Selaginella moellendorffii 44.01 4.00e-76 280.00
IUUC-Sit-110765 Setaria italica 39.35 2.00e-62 234.00
IUUC-Sly-111527 Solanum lycopersicum 43.65 2.00e-71 265.00
IUUC-Stu-112899 Solanum tuberosum 43.65 1.00e-71 265.00
IUUC-Sar-112986 Sorex araneus 96.24 0.00e+00 2697.00
IUUC-Sbi-114604 Sorghum bicolor 40.48 5.00e-65 243.00
IUUC-Sre-115191 Sporisorium reilianum 43.08 9.00e-64 239.00
IUUC-Ssc-115440 Sus scrofa 95.58 0.00e+00 2657.00
IUUC-Tgu-116633 Taeniopygia guttata 89.58 0.00e+00 2555.00
IUUC-Tru-118439 Takifugu rubripes 78.92 0.00e+00 2244.00
IUUC-Tsy-119472 Tarsius syrichta 89.96 0.00e+00 1433.00
IUUC-Tni-119808 Tetraodon nigroviridis 74.76 0.00e+00 2037.00
IUUC-Tca-121648 Theobroma cacao 46.99 3.00e-72 267.00
IUUC-Tre-122161 Trichoderma reesei 34.54 3.00e-123 437.00
IUUC-Tvi-122575 Trichoderma virens 33.26 2.00e-114 407.00
IUUC-Tae-123381 Triticum aestivum 44.11 1.00e-65 245.00
IUUC-Tur-126291 Triticum urartu 42.01 2.00e-66 248.00
IUUC-Tme-126979 Tuber melanosporum 37.12 3.00e-147 516.00
IUUC-Tbe-127576 Tupaia belangeri 79.65 0.00e+00 911.00
IUUC-Ttr-129106 Tursiops truncatus 98.64 0.00e+00 1318.00
IUUC-Uma-129633 Ustilago maydis 41.93 5.00e-72 267.00
IUUC-Vda-130001 Verticillium dahliae 45.63 2.00e-75 278.00
IUUC-Vpa-130733 Vicugna pacos 89.89 0.00e+00 1323.00
IUUC-Vvi-131318 Vitis vinifera 44.03 3.00e-69 257.00
IUUC-Xtr-131908 Xenopus tropicalis 85.72 0.00e+00 2451.00
IUUC-Xma-133331 Xiphophorus maculatus 79.97 0.00e+00 2245.00
IUUC-Yli-134651 Yarrowia lipolytica 37.10 2.00e-119 424.00
IUUC-Zma-135850 Zea mays 39.95 4.00e-65 243.00
Created Date 25-Jun-2017

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