iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118428

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Suppressor of cytokine signaling 3a

Genbank Nucleotide ID

DQ335254

Gene Name

socs3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000011640.1	ENSTRUT00000029541.1	ENSTRUP00000029424.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	54.15	4.00e-67	251.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MVTHSKFSNA MSSSLFDSNM RLPHHYKTFN SKSQYQMVLA TLHKLQESGF YWGAITGKDA 60
NVMLAAEDAG TFLIRDSSDN RHLFALSIKT ASGTKNLRIQ CDSSSFYLQT DPKNIQTVPH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGCCGCCTC GCAAAGTTTT AGTGTGGGCC AACCGTTAAC TTTGGATTTT ATCTGCTGTT 60
TTTCCTTGAA GAGAACCTAC AGAAACACTT TTAAGGTAAG CAAGGCTGCT TTTTGTTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination

KEGG

tru:778006

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	53.71	1.00e-65	242.00
IUUC-Apl-003607	Anas platyrhynchos	62.93	6.00e-65	239.00
IUUC-Aca-005063	Anolis carolinensis	57.67	6.00e-66	243.00
IUUC-Ame-010859	Astyanax mexicanus	56.70	9.00e-77	279.00
IUUC-Bta-012817	Bos taurus	53.22	3.00e-66	244.00
IUUC-Bra-017963	Brassica rapa	22.47	1.30e+00	28.10
IUUC-Cja-019605	Callithrix jacchus	54.15	7.00e-67	246.00
IUUC-Cfa-021231	Canis familiaris	54.15	1.00e-66	246.00
IUUC-Cpo-022003	Cavia porcellus	53.45	2.00e-66	244.00
IUUC-Csa-023511	Chlorocebus sabaeus	54.59	3.00e-67	247.00
IUUC-Dre-028536	Danio rerio	63.33	6.00e-81	293.00
IUUC-Dno-029003	Dasypus novemcinctus	54.82	5.00e-68	250.00
IUUC-Eca-034205	Equus caballus	48.04	1.00e-41	161.00
IUUC-Fca-036317	Felis catus	52.40	3.00e-64	238.00
IUUC-Gmo-038777	Gadus morhua	54.55	5.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	61.03	2.00e-63	235.00
IUUC-Gac-041837	Gasterosteus aculeatus	79.51	2.00e-90	324.00
IUUC-Ggo-045620	Gorilla gorilla	54.59	3.00e-67	247.00
IUUC-Hsa-046909	Homo sapiens	54.59	3.00e-67	247.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	52.52	2.00e-66	244.00
IUUC-Lch-049510	Latimeria chalumnae	63.77	2.00e-73	267.00
IUUC-Loc-052863	Lepisosteus oculatus	70.67	1.00e-87	315.00
IUUC-Laf-054136	Loxodonta africana	54.74	3.00e-67	247.00
IUUC-Mcc-055383	Macaca mulatta	54.59	3.00e-67	247.00
IUUC-Meu-056153	Macropus eugenii	53.04	7.00e-66	243.00
IUUC-Mmr-061185	Microcebus murinus	54.35	1.00e-66	245.00
IUUC-Mdo-061819	Monodelphis domestica	52.84	9.00e-66	242.00
IUUC-Mmu-064231	Mus musculus	55.46	5.00e-68	250.00
IUUC-Mpu-066691	Mustela putorius furo	54.15	1.00e-66	246.00
IUUC-Mlu-067673	Myotis lucifugus	55.22	5.00e-68	250.00
IUUC-Ont-072406	Oreochromis niloticus	73.66	2.00e-91	327.00
IUUC-Oan-073249	Ornithorhynchus anatinus	56.59	7.00e-64	236.00
IUUC-Ogu-078262	Oryza glumaepatula	23.91	2.20e+00	28.10
IUUC-Ola-087373	Oryzias latipes	48.39	4.00e-53	200.00
IUUC-Oga-088041	Otolemur garnettii	54.82	2.00e-67	248.00
IUUC-Oar-089646	Ovis aries	51.07	1.00e-62	232.00
IUUC-Ptr-091502	Pan troglodytes	54.59	3.00e-67	247.00
IUUC-Pan-091934	Papio anubis	54.59	3.00e-67	247.00
IUUC-Pfo-096412	Poecilia formosa	50.25	1.00e-56	212.00
IUUC-Pab-098554	Pongo abelii	54.59	3.00e-67	247.00
IUUC-Rno-105874	Rattus norvegicus	55.02	1.00e-67	248.00
IUUC-Sha-107151	Sarcophilus harrisii	52.59	1.00e-65	242.00
IUUC-Ssc-115722	Sus scrofa	50.59	2.00e-41	160.00
IUUC-Tgu-117151	Taeniopygia guttata	60.09	5.00e-62	230.00
IUUC-Tni-120590	Tetraodon nigroviridis	88.56	2.00e-107	380.00
IUUC-Ttr-129065	Tursiops truncatus	53.65	9.00e-67	246.00
IUUC-Xtr-132167	Xenopus tropicalis	59.51	6.00e-67	246.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence