iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132167

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Suppressor of cytokine signaling 3; Suppressor of cytokine-signaling 3

Genbank Nucleotide ID

AAMC01051347

Gene Name

socs3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000024632.2	ENSXETT00000053080.2	ENSXETP00000053080.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	65.78	2.00e-80	295.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MVTQSKFPSM SRALDSSLRL KTFSSRSEYN LVLTAVRKLQ ESGFYWSTVT GSQANLLLST 60
EPAGTFLIRD SSDRRHFFTL SVKTESGTKN LRIQCEPCGF SLQTDPRSAQ PVPRFDCVLK 120

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Nucleotide Sequence
(Fasta)

CTTGTGAGAC AGCAATAGTA TACACTTTTT AACACAGCTT GGACTATCCC AGGACTATCA 60
CAGGGGTCTG AAAGTGACCA AAGCAGCTGG GACATATTCG TTATCTGCCT TTGAATATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0016567--P:protein ubiquitination

KEGG

xtr:448204

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	64.89	2.00e-79	288.00
IUUC-Apl-003607	Anas platyrhynchos	75.12	5.00e-78	283.00
IUUC-Aca-005063	Anolis carolinensis	70.95	5.00e-82	296.00
IUUC-Ame-010859	Astyanax mexicanus	54.46	4.00e-65	240.00
IUUC-Bta-012817	Bos taurus	65.50	3.00e-82	297.00
IUUC-Cja-019605	Callithrix jacchus	66.22	1.00e-80	291.00
IUUC-Cfa-021231	Canis familiaris	64.89	2.00e-79	288.00
IUUC-Cpo-022003	Cavia porcellus	64.47	5.00e-79	286.00
IUUC-Csa-023511	Chlorocebus sabaeus	65.78	3.00e-80	290.00
IUUC-Dre-028536	Danio rerio	61.90	1.00e-71	262.00
IUUC-Dno-029003	Dasypus novemcinctus	65.62	4.00e-81	293.00
IUUC-Eca-034205	Equus caballus	55.31	2.00e-49	187.00
IUUC-Fca-036317	Felis catus	64.57	5.00e-78	283.00
IUUC-Gmo-038777	Gadus morhua	56.80	1.00e-35	141.00
IUUC-Gga-041258	Gallus gallus	71.77	7.00e-75	273.00
IUUC-Gac-041837	Gasterosteus aculeatus	54.63	4.00e-64	236.00
IUUC-Ggo-045620	Gorilla gorilla	65.78	3.00e-80	290.00
IUUC-Hsa-046909	Homo sapiens	65.78	3.00e-80	290.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	63.68	6.00e-80	289.00
IUUC-Lch-049510	Latimeria chalumnae	69.27	1.00e-80	292.00
IUUC-Loc-052863	Lepisosteus oculatus	66.83	8.00e-77	279.00
IUUC-Laf-054136	Loxodonta africana	64.04	4.00e-80	290.00
IUUC-Mcc-055383	Macaca mulatta	65.78	3.00e-80	290.00
IUUC-Meu-056153	Macropus eugenii	65.49	6.00e-81	293.00
IUUC-Mmr-061185	Microcebus murinus	65.04	3.00e-79	287.00
IUUC-Mdo-061819	Monodelphis domestica	65.78	9.00e-81	292.00
IUUC-Mmu-064231	Mus musculus	66.67	2.00e-81	294.00
IUUC-Mpu-066691	Mustela putorius furo	64.89	2.00e-79	288.00
IUUC-Mlu-067673	Myotis lucifugus	65.04	2.00e-80	291.00
IUUC-Ont-072406	Oreochromis niloticus	58.05	2.00e-66	244.00
IUUC-Oan-073249	Ornithorhynchus anatinus	70.15	2.00e-77	281.00
IUUC-Ola-087373	Oryzias latipes	51.89	7.00e-52	196.00
IUUC-Oga-088041	Otolemur garnettii	65.62	1.00e-79	288.00
IUUC-Oar-089646	Ovis aries	63.32	5.00e-77	280.00
IUUC-Ptr-091502	Pan troglodytes	65.78	3.00e-80	290.00
IUUC-Pan-091934	Papio anubis	65.78	3.00e-80	290.00
IUUC-Pfo-096412	Poecilia formosa	47.76	7.00e-50	189.00
IUUC-Pab-098554	Pongo abelii	65.78	3.00e-80	290.00
IUUC-Rno-105874	Rattus norvegicus	66.22	5.00e-81	293.00
IUUC-Sha-107151	Sarcophilus harrisii	64.91	1.00e-80	292.00
IUUC-Ssc-115722	Sus scrofa	56.47	7.00e-46	176.00
IUUC-Tgu-117151	Taeniopygia guttata	72.25	3.00e-75	274.00
IUUC-Tru-118428	Takifugu rubripes	59.51	5.00e-67	246.00
IUUC-Tni-120590	Tetraodon nigroviridis	59.02	9.00e-67	245.00
IUUC-Ttr-129065	Tursiops truncatus	64.63	9.00e-80	289.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence