iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117871

UUCD1 version

UUC-TaR-00793

Ensembl Protein ID

ENSTRUP00000037358.1

UniProt Accession

H2UK87; H2UK87_TAKRU

Protein Name

Uncharacterized protein

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000014622.1	ENSTRUT00000037492.1	ENSTRUP00000037357.1
ENSTRUG00000014622.1	ENSTRUT00000037493.1	ENSTRUP00000037358.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.30e-37	125.4	234	267
UBD/Beta-Prp	1.00e-63	216.5	55	277

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H+++v+++++ +d t l+s+s+D+t+k+WD+  g
   Q: 234  HNGGVYAVSWsPDsTQLISASGDKTVKLWDVGAG 267
           9**********999****************8655 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD...rtikvwdlstgkcvht 89
            ++h +++t+ k+sp++ ++a+g ++g++++wd+t++  l ++     +++++++ + +d+k  + ++ D   +++ v+  ++g++v  
   Q: 55   YTEHAHQVTVAKYSPSGFYIASGDASGKVRIWDTTQKEHLLKYeyNPISGKIKDIAWTEDSKR-MAVAGDgreKFAAVFLWDSGSTVGD 142
           5678999*****************************999888842345899*********965.5555555999999**99******** PP
   S: 90   lkghedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.. 175
           l  h++ + s+++ +++ ++l++Gs+d+ +  ++ +  +    t ++h+++vncv+++pdg+l+v++s+D+++ + d +tg+ +  l  
   Q: 143  LACHSKVINSVDIRQKRpYRLITGSDDNCASFFEGPPFKFKF-TATQHNQFVNCVRFSPDGSLFVTASADGQILVCDGSTGEKVGALgg 230
           ***************888******************999999.********************************************** PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
           +++h++ vy +s+++++++l+s+s d+tvklwd+ +g+ v t++  t
   Q: 231  EKAHNGGVYAVSWSPDSTQLISASGDKTVKLWDVGAGTAVTTFKLGT 277
           888************************************99998655 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

TWPFRIESVF ASLPQMERGV SKVIGGDPKN NNFLYTNGKS VIIRNIENPA IADIYTEHAH 60
QVTVAKYSPS GFYIASGDAS GKVRIWDTTQ KEHLLKYEYN PISGKIKDIA WTEDSKRMAV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGTGACCA GGGAGTGCAC CGCTGGGGAA GCGTCACTGT CTCCACTGTT TCATTCATTT 60
GGACGAGAAA CGTCAGGCTA GCGAACAGCA GCGAAAAATG ACGCACCAGC AGAGTAAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0042643--C:actomyosin, actin portion
GO:0030864--C:cortical actin cytoskeleton
GO:0051015--F:actin filament binding
GO:0030042--P:actin filament depolymerization
GO:0040011--P:locomotion
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	35.28	2.00e-81	296.00
IUUC-Aml-002368	Ailuropoda melanoleuca	71.05	0.00e+00	902.00
IUUC-Atr-003160	Amborella trichopoda	37.13	8.00e-116	410.00
IUUC-Apl-004012	Anas platyrhynchos	70.08	0.00e+00	883.00
IUUC-Aca-004707	Anolis carolinensis	68.76	0.00e+00	880.00
IUUC-Aly-006465	Arabidopsis lyrata	37.52	1.00e-111	396.00
IUUC-Ath-006740	Arabidopsis thaliana	37.03	2.00e-110	393.00
IUUC-Ago-007920	Ashbya gossypii	27.77	8.00e-75	274.00
IUUC-Acl-008262	Aspergillus clavatus	35.73	2.00e-101	363.00
IUUC-Afl-008471	Aspergillus flavus	31.44	4.00e-77	282.00
IUUC-Afu-008989	Aspergillus fumigatus	35.37	4.00e-92	332.00
IUUC-Ani-009167	Aspergillus nidulans	34.75	1.00e-108	387.00
IUUC-Ang-009595	Aspergillus niger	36.77	1.00e-100	360.00
IUUC-Aor-009908	Aspergillus oryzae	34.76	7.00e-101	361.00
IUUC-Ate-010580	Aspergillus terreus	34.76	3.00e-106	380.00
IUUC-Ame-011269	Astyanax mexicanus	59.75	1.00e-133	469.00
IUUC-Bgr-011996	Blumeria graminis	33.99	5.00e-104	371.00
IUUC-Bta-013278	Bos taurus	70.58	0.00e+00	925.00
IUUC-Bci-013925	Botrytis cinerea	34.93	3.00e-106	379.00
IUUC-Bdi-014659	Brachypodium distachyon	36.57	3.00e-106	379.00
IUUC-Bol-016043	Brassica oleracea	35.40	8.00e-109	387.00
IUUC-Bra-017139	Brassica rapa	36.50	1.00e-110	393.00
IUUC-Cel-018417	Caenorhabditis elegans	38.92	3.00e-120	425.00
IUUC-Cja-019952	Callithrix jacchus	70.08	0.00e+00	887.00
IUUC-Cfa-020225	Canis familiaris	70.91	0.00e+00	912.00
IUUC-Cpo-021900	Cavia porcellus	69.72	0.00e+00	894.00
IUUC-Csa-023028	Chlorocebus sabaeus	70.08	0.00e+00	886.00
IUUC-Cho-025030	Choloepus hoffmanni	52.68	4.00e-165	574.00
IUUC-Cin-025152	Ciona intestinalis	51.59	2.00e-73	268.00
IUUC-Csv-025986	Ciona savignyi	37.98	1.00e-91	330.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	36.95	5.00e-108	385.00
IUUC-Cne-026814	Cryptococcus neoformans	32.41	4.00e-95	342.00
IUUC-Dre-027498	Danio rerio	77.72	2.00e-91	328.00
IUUC-Dno-029383	Dasypus novemcinctus	69.26	0.00e+00	875.00
IUUC-Dor-030633	Dipodomys ordii	68.27	0.00e+00	810.00
IUUC-Dse-031526	Dothistroma septosporum	35.61	2.00e-109	389.00
IUUC-Dme-031597	Drosophila melanogaster	45.79	7.00e-163	567.00
IUUC-Ete-032780	Echinops telfairi	63.64	0.00e+00	798.00
IUUC-Eca-034306	Equus caballus	69.00	0.00e+00	868.00
IUUC-Eeu-034531	Erinaceus europaeus	59.81	2.00e-112	399.00
IUUC-Fca-036301	Felis catus	70.38	0.00e+00	912.00
IUUC-Fal-037361	Ficedula albicollis	72.07	0.00e+00	936.00
IUUC-Fox-037924	Fusarium oxysporum	35.19	6.00e-104	371.00
IUUC-Fso-038199	Fusarium solani	34.10	5.00e-98	351.00
IUUC-Gmo-039238	Gadus morhua	72.89	0.00e+00	899.00
IUUC-Ggr-039830	Gaeumannomyces graminis	34.48	1.00e-95	343.00
IUUC-Gga-040235	Gallus gallus	71.40	0.00e+00	910.00
IUUC-Gac-042363	Gasterosteus aculeatus	77.48	0.00e+00	965.00
IUUC-Gma-044189	Glycine max	37.73	1.00e-114	407.00
IUUC-Ggo-044632	Gorilla gorilla	68.32	0.00e+00	858.00
IUUC-Hsa-045792	Homo sapiens	69.75	0.00e+00	902.00
IUUC-Hvu-047517	Hordeum vulgare	36.51	1.00e-110	393.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	70.55	0.00e+00	902.00
IUUC-Kpa-049183	Komagataella pastoris	32.13	4.00e-82	298.00
IUUC-Lch-050428	Latimeria chalumnae	68.10	0.00e+00	892.00
IUUC-Lpe-051306	Leersia perrieri	37.17	4.00e-113	401.00
IUUC-Loc-052096	Lepisosteus oculatus	64.76	0.00e+00	801.00
IUUC-Lma-053313	Leptosphaeria maculans	36.48	3.00e-114	408.00
IUUC-Laf-054060	Loxodonta africana	69.09	0.00e+00	871.00
IUUC-Mcc-055619	Macaca mulatta	68.53	0.00e+00	862.00
IUUC-Meu-056689	Macropus eugenii	55.54	0.00e+00	683.00
IUUC-Mor-056940	Magnaporthe oryzae	34.26	1.00e-94	340.00
IUUC-Mpo-057557	Magnaporthe poae	26.56	7.00e-56	211.00
IUUC-Mtr-058478	Medicago truncatula	37.66	2.00e-115	409.00
IUUC-Mla-059103	Melampsora laricipopulina	30.43	3.00e-75	276.00
IUUC-Mga-060150	Meleagris gallopavo	71.36	0.00e+00	906.00
IUUC-Mvi-060448	Microbotryum violaceum	32.73	3.00e-79	289.00
IUUC-Mmr-061226	Microcebus murinus	69.09	0.00e+00	870.00
IUUC-Mdo-062674	Monodelphis domestica	70.08	0.00e+00	907.00
IUUC-Mmu-064170	Mus musculus	69.75	0.00e+00	895.00
IUUC-Mac-065124	Musa acuminata	38.65	1.00e-117	416.00
IUUC-Mpu-066001	Mustela putorius furo	67.52	0.00e+00	884.00
IUUC-Mlu-067253	Myotis lucifugus	69.72	0.00e+00	889.00
IUUC-Nfi-068550	Neosartorya fischeri	35.92	3.00e-107	382.00
IUUC-Ncr-068948	Neurospora crassa	34.52	4.00e-108	385.00
IUUC-Nle-070115	Nomascus leucogenys	67.14	0.00e+00	800.00
IUUC-Opr-070254	Ochotona princeps	68.78	0.00e+00	851.00
IUUC-Ont-071666	Oreochromis niloticus	79.67	0.00e+00	996.00
IUUC-Oan-073594	Ornithorhynchus anatinus	64.56	8.00e-120	423.00
IUUC-Ocu-074824	Oryctolagus cuniculus	68.93	0.00e+00	866.00
IUUC-Oba-075010	Oryza barthii	36.68	8.00e-112	397.00
IUUC-Obr-076364	Oryza brachyantha	37.34	2.00e-113	402.00
IUUC-Ogl-077019	Oryza glaberrima	36.68	8.00e-112	397.00
IUUC-Ogu-078496	Oryza glumaepatula	36.68	8.00e-112	397.00
IUUC-Oin-080116	Oryza indica	36.84	3.00e-112	399.00
IUUC-Olo-080290	Oryza longistaminata	36.68	1.00e-111	397.00
IUUC-Ome-081969	Oryza meridionalis	36.68	9.00e-112	397.00
IUUC-Oni-082075	Oryza nivara	36.68	7.00e-112	397.00
IUUC-Opu-083959	Oryza punctata	36.89	3.00e-112	399.00
IUUC-Oru-084711	Oryza rufipogon	36.68	8.00e-112	397.00
IUUC-Osa-085958	Oryza sativa	36.84	3.00e-112	399.00
IUUC-Ola-086968	Oryzias latipes	79.34	0.00e+00	988.00
IUUC-Oga-089108	Otolemur garnettii	69.84	0.00e+00	912.00
IUUC-Oar-089986	Ovis aries	66.23	0.00e+00	842.00
IUUC-Ptr-091281	Pan troglodytes	70.28	0.00e+00	899.00
IUUC-Pan-092585	Papio anubis	70.08	0.00e+00	888.00
IUUC-Psi-093811	Pelodiscus sinensis	69.77	0.00e+00	921.00
IUUC-Pma-094396	Petromyzon marinus	64.98	0.00e+00	852.00
IUUC-Pno-095086	Phaeosphaeria nodorum	34.98	1.00e-106	380.00
IUUC-Ppa-095876	Physcomitrella patens	36.74	6.00e-117	414.00
IUUC-Pfo-096973	Poecilia formosa	81.65	0.00e+00	1051.00
IUUC-Pab-098391	Pongo abelii	69.92	0.00e+00	885.00
IUUC-Pop-098850	Populus trichocarpa	37.34	6.00e-114	404.00
IUUC-Pca-100257	Procavia capensis	40.74	1.00e-57	218.00
IUUC-Ppe-101578	Prunus persica	38.42	6.00e-115	407.00
IUUC-Pva-102872	Pteropus vampyrus	66.17	0.00e+00	850.00
IUUC-Pgr-103593	Puccinia graminis	32.84	1.00e-83	304.00
IUUC-Pte-104365	Pyrenophora teres	36.59	1.00e-105	377.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	36.26	1.00e-108	387.00
IUUC-Rno-105737	Rattus norvegicus	69.92	0.00e+00	917.00
IUUC-Sce-106383	Saccharomyces cerevisiae	28.01	7.00e-67	248.00
IUUC-Sha-107084	Sarcophilus harrisii	67.38	0.00e+00	786.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	34.88	5.00e-108	384.00
IUUC-Spo-108309	Schizosaccharomyces pombe	32.78	4.00e-92	332.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	35.42	1.00e-107	384.00
IUUC-Smo-109255	Selaginella moellendorffii	34.54	2.00e-102	366.00
IUUC-Sit-109962	Setaria italica	37.54	1.00e-114	407.00
IUUC-Sly-110897	Solanum lycopersicum	38.32	5.00e-116	411.00
IUUC-Stu-111971	Solanum tuberosum	38.34	8.00e-116	410.00
IUUC-Sar-113415	Sorex araneus	61.25	9.00e-93	334.00
IUUC-Sbi-114857	Sorghum bicolor	37.38	3.00e-113	402.00
IUUC-Sre-114900	Sporisorium reilianum	32.35	2.00e-87	316.00
IUUC-Tgu-117256	Taeniopygia guttata	72.26	0.00e+00	934.00
IUUC-Tsy-119172	Tarsius syrichta	76.57	8.00e-112	397.00
IUUC-Tni-120339	Tetraodon nigroviridis	85.48	0.00e+00	1090.00
IUUC-Tca-121609	Theobroma cacao	38.16	4.00e-113	402.00
IUUC-Tre-122076	Trichoderma reesei	34.48	1.00e-95	343.00
IUUC-Tvi-122528	Trichoderma virens	33.88	7.00e-98	351.00
IUUC-Tae-124549	Triticum aestivum	36.35	6.00e-110	391.00
IUUC-Tur-126845	Triticum urartu	35.26	2.00e-79	289.00
IUUC-Tme-127217	Tuber melanosporum	35.78	4.00e-106	378.00
IUUC-Tbe-127526	Tupaia belangeri	67.66	0.00e+00	867.00
IUUC-Ttr-128898	Tursiops truncatus	63.04	0.00e+00	808.00
IUUC-Uma-129631	Ustilago maydis	31.17	6.00e-91	328.00
IUUC-Vda-129732	Verticillium dahliae	34.57	5.00e-83	301.00
IUUC-Vvi-131217	Vitis vinifera	38.92	5.00e-116	411.00
IUUC-Xtr-132860	Xenopus tropicalis	65.85	0.00e+00	848.00
IUUC-Xma-133830	Xiphophorus maculatus	81.65	0.00e+00	1052.00
IUUC-Yli-134335	Yarrowia lipolytica	31.61	4.00e-72	265.00
IUUC-Zma-135907	Zea mays	36.89	2.00e-112	399.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence