iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060025

UUCD1 version

UUC-MeG-00715

Ensembl Protein ID

ENSMGAP00000017080.1

UniProt Accession

G1NS71; G1NS71_MELGA

Protein Name

Uncharacterized protein

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000016138.1	ENSMGAT00000018054.1	ENSMGAP00000017080.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.50e-19	69.1	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.50e-08	32.4	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaasS++F+a+f+++l+es   ++v+++d + pev++ ll+F Y++++ +ne
   Q: 46   TDVTLWAGNRSFPCHRAVLAASSRYFEAMFSNGLRESL-DDEVNFHDsLHPEVLELLLDFAYSSRIIINE 114
           7************************************9.*******99*****************99987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclg++ ++d+++c++L++   +++l +F+
   Q: 146  PSNCLGMMLLSDAHQCRRLYELSWRMCLVNFE 177
           89****************************95 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MSVSVHENRK SRTSTGSMNI LLFHKASHPD CVLSHLNTLR KHCMFTDVTL WAGNRSFPCH 60
RAVLAASSRY FEAMFSNGLR ESLDDEVNFH DSLHPEVLEL LLDFAYSSRI IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGTCA GCGTCCACGA GAACCGCAAA TCCCGGACGA GCACGGGCTC CATGAACATC 60
CTGCTTTTCC ACAAAGCTTC CCACCCAGAC TGCGTCTTAT CCCACCTGAA CACCCTCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

KEGG

mgp:100550504

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	90.49	0.00e+00	1138.00
IUUC-Apl-003543	Anas platyrhynchos	98.81	0.00e+00	1182.00
IUUC-Aca-004729	Anolis carolinensis	92.02	0.00e+00	1127.00
IUUC-Ame-011020	Astyanax mexicanus	87.27	0.00e+00	1060.00
IUUC-Bta-012955	Bos taurus	88.79	0.00e+00	1120.00
IUUC-Bci-013875	Botrytis cinerea	27.00	5.00e-16	78.20
IUUC-Cja-018839	Callithrix jacchus	89.81	0.00e+00	1130.00
IUUC-Cfa-020224	Canis familiaris	90.83	0.00e+00	1139.00
IUUC-Cpo-021593	Cavia porcellus	86.93	0.00e+00	1054.00
IUUC-Csa-023276	Chlorocebus sabaeus	90.49	0.00e+00	1138.00
IUUC-Cho-024542	Choloepus hoffmanni	76.40	0.00e+00	944.00
IUUC-Dre-028053	Danio rerio	87.27	0.00e+00	1037.00
IUUC-Dno-029287	Dasypus novemcinctus	88.29	0.00e+00	1114.00
IUUC-Dor-030908	Dipodomys ordii	82.17	0.00e+00	1008.00
IUUC-Ete-032817	Echinops telfairi	73.01	0.00e+00	889.00
IUUC-Eca-033651	Equus caballus	76.57	0.00e+00	945.00
IUUC-Fca-035897	Felis catus	90.32	0.00e+00	1135.00
IUUC-Fal-037036	Ficedula albicollis	98.98	0.00e+00	1187.00
IUUC-Gmo-039345	Gadus morhua	85.40	0.00e+00	1011.00
IUUC-Gga-040404	Gallus gallus	99.66	0.00e+00	1194.00
IUUC-Gac-042447	Gasterosteus aculeatus	85.40	0.00e+00	1025.00
IUUC-Ggo-045060	Gorilla gorilla	90.32	0.00e+00	1137.00
IUUC-Hsa-046494	Homo sapiens	90.32	0.00e+00	1137.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	90.83	0.00e+00	1136.00
IUUC-Lch-050211	Latimeria chalumnae	88.29	0.00e+00	1077.00
IUUC-Loc-052578	Lepisosteus oculatus	86.25	0.00e+00	1058.00
IUUC-Laf-053498	Loxodonta africana	90.83	0.00e+00	1088.00
IUUC-Mcc-055033	Macaca mulatta	90.49	0.00e+00	1139.00
IUUC-Meu-056893	Macropus eugenii	92.70	0.00e+00	1157.00
IUUC-Mor-057181	Magnaporthe oryzae	26.01	3.00e-10	58.90
IUUC-Mmr-060658	Microcebus murinus	89.47	0.00e+00	1129.00
IUUC-Mdo-062667	Monodelphis domestica	93.04	0.00e+00	1158.00
IUUC-Mmu-063125	Mus musculus	88.46	0.00e+00	1077.00
IUUC-Mpu-066209	Mustela putorius furo	90.49	0.00e+00	1139.00
IUUC-Mlu-068237	Myotis lucifugus	87.95	0.00e+00	1081.00
IUUC-Nle-069454	Nomascus leucogenys	90.39	0.00e+00	1124.00
IUUC-Opr-070238	Ochotona princeps	76.40	0.00e+00	942.00
IUUC-Ont-072138	Oreochromis niloticus	86.25	0.00e+00	1018.00
IUUC-Oan-073320	Ornithorhynchus anatinus	84.89	0.00e+00	1063.00
IUUC-Ocu-073765	Oryctolagus cuniculus	85.57	0.00e+00	1053.00
IUUC-Ola-086620	Oryzias latipes	72.50	0.00e+00	904.00
IUUC-Oga-088002	Otolemur garnettii	89.30	0.00e+00	1119.00
IUUC-Oar-089481	Ovis aries	88.46	0.00e+00	1118.00
IUUC-Ptr-091200	Pan troglodytes	90.15	0.00e+00	1132.00
IUUC-Pan-092098	Papio anubis	76.57	0.00e+00	945.00
IUUC-Psi-093884	Pelodiscus sinensis	95.93	0.00e+00	1162.00
IUUC-Pma-094515	Petromyzon marinus	59.48	0.00e+00	669.00
IUUC-Pno-095143	Phaeosphaeria nodorum	26.91	1.00e-14	73.60
IUUC-Pfo-097496	Poecilia formosa	76.06	0.00e+00	959.00
IUUC-Pab-098388	Pongo abelii	76.57	0.00e+00	945.00
IUUC-Pca-100511	Procavia capensis	70.46	0.00e+00	852.00
IUUC-Pva-102321	Pteropus vampyrus	89.30	0.00e+00	1122.00
IUUC-Rno-104835	Rattus norvegicus	87.78	0.00e+00	1071.00
IUUC-Sha-107528	Sarcophilus harrisii	92.87	0.00e+00	1159.00
IUUC-Sar-113403	Sorex araneus	76.23	0.00e+00	967.00
IUUC-Ssc-116161	Sus scrofa	89.98	0.00e+00	1132.00
IUUC-Tgu-116569	Taeniopygia guttata	98.81	0.00e+00	1184.00
IUUC-Tru-117890	Takifugu rubripes	75.38	0.00e+00	954.00
IUUC-Tni-120525	Tetraodon nigroviridis	76.65	0.00e+00	893.00
IUUC-Ttr-129297	Tursiops truncatus	89.47	0.00e+00	1127.00
IUUC-Xtr-132302	Xenopus tropicalis	87.61	0.00e+00	1098.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence