iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Smo-109533

Ensembl Protein ID

EFJ23133

UniProt Accession

D8RWR3; D8RWR3_SELML

Genbank Protein ID

EFJ23133.1

Protein Name

Protein HIRA

Genbank Nucleotide ID

GL377593

Gene Name

HIRA1-2; SELMODRAFT_267866

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SELMODRAFT_267866	EFJ23133	EFJ23133

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.00e-26	91.1	123	154

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gHt++v +la+ +d  +l+++s D+t+++W +
   Q: 123  GHTADVVDLAWsPDdSMLATCSLDNTVRIWKM 154
           8***********777***************97 PP

Organism

Selaginella moellendorffii

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MIVEKPEWLR HEGLQIFSVD FQPSGQRCAT AGGDHKVRIW NTRPLMKEGE ADRGGEKLLA 60
TLCDHFGSVN CVRWSKSGLY VASGSDGSLV LIHEKRHGTG TVEFGSGEPA NVENWKVCAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTGTGG AGAAGCCGGA ATGGCTCCGT CACGAGGGCC TCCAGATCTT CTCGGTGGAT 60
TTCCAGCCTA GCGGGCAGCG ATGCGCCACA GCCGGGGGCG ATCACAAGGT ATGTGTATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

smo:SELMODRAFT_267866

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003197	Anas platyrhynchos	35.67	1.00e-80	293.00
IUUC-Ago-007766	Ashbya gossypii	31.24	1.00e-58	221.00
IUUC-Ame-011094	Astyanax mexicanus	27.96	7.00e-37	147.00
IUUC-Cja-018987	Callithrix jacchus	36.53	1.00e-75	276.00
IUUC-Csa-023081	Chlorocebus sabaeus	37.63	7.00e-87	314.00
IUUC-Cho-024510	Choloepus hoffmanni	27.72	9.00e-19	87.40
IUUC-Cin-025182	Ciona intestinalis	37.08	7.00e-84	305.00
IUUC-Cme-027349	Cyanidioschyzon merolae	30.63	8.00e-56	211.00
IUUC-Dor-030687	Dipodomys ordii	34.73	6.00e-66	244.00
IUUC-Dme-031746	Drosophila melanogaster	38.05	2.00e-89	323.00
IUUC-Ete-032384	Echinops telfairi	32.98	3.00e-63	236.00
IUUC-Ggr-040016	Gaeumannomyces graminis	32.68	6.00e-66	245.00
IUUC-Gac-041405	Gasterosteus aculeatus	36.31	2.00e-82	299.00
IUUC-Ggo-045430	Gorilla gorilla	37.63	8.00e-87	314.00
IUUC-Hsa-046442	Homo sapiens	37.63	6.00e-87	315.00
IUUC-Laf-053718	Loxodonta africana	37.04	6.00e-88	318.00
IUUC-Mmr-060871	Microcebus murinus	37.42	7.00e-86	311.00
IUUC-Mdo-062301	Monodelphis domestica	37.04	2.00e-85	310.00
IUUC-Mmu-063888	Mus musculus	37.58	1.00e-86	313.00
IUUC-Mlu-067542	Myotis lucifugus	36.79	1.00e-82	300.00
IUUC-Nle-070156	Nomascus leucogenys	37.42	2.00e-86	313.00
IUUC-Opr-070808	Ochotona princeps	35.31	2.00e-53	203.00
IUUC-Oan-073675	Ornithorhynchus anatinus	28.72	9.00e-39	154.00
IUUC-Opu-084008	Oryza punctata	52.51	0.00e+00	873.00
IUUC-Olu-087611	Ostreococcus lucimarinus	46.28	2.00e-119	422.00
IUUC-Ptr-090715	Pan troglodytes	37.63	6.00e-87	315.00
IUUC-Pan-092318	Papio anubis	37.30	3.00e-83	302.00
IUUC-Pab-098047	Pongo abelii	37.63	6.00e-87	315.00
IUUC-Rno-105566	Rattus norvegicus	37.99	1.00e-86	313.00
IUUC-Sar-113222	Sorex araneus	35.70	3.00e-75	276.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence