iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092247

Ensembl Protein ID

ENSPANP00000011441.1

UniProt Accession

A0A096NEV5; A0A096NEV5_PAPAN

Genbank Protein ID

ENSPANP00000011441

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01012160

Gene Name

UBE2D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000005002.1	ENSPANT00000008139.1	ENSPANP00000011441.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.50e-54	181.3	5	132
UBD/UBC-like/UBD_UBC	4.30e-79	263.4	5	134

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  
   Q: 5    RINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR-- 90
           89**********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
           ++Wspal++++vllsi+sll++pnp++pl  e+a+++k++r 
   Q: 91   SQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRD 132
           ***************************************997 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqw
   Q: 5    RINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkeky 130
           s+alt+skvlls+csll+d++pddplv+eiariyktd+++ 
   Q: 94   SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDNV 134
           **************************************975 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCCTGTGT CTGGCAGAGC CGCTGTGAGA CGAGACAATC CTGCCCCGCC GCCGGGATAA 60
TCAAGAGTTT TGGCCGGACC TTTGAGCATA CACCGAGTGA GTGAGGAGCC AGACGACAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence