iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000064

Ensembl Protein ID

EMT27309

UniProt Accession

M8BZC4; M8BZC4_AEGTA

Genbank Protein ID

EMT27309.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

KD511499

Gene Name

F775_07673

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_07673	EMT27309	EMT27309

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-39	131.6	50	86
UBD/Beta-Prp	1.30e-77	261.7	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++t+++l
   Q: 50   HDGPVRGVHFhaTQPLFVSGGDDYKIKVWNYKTHRCL 86
           99*********6449********************98 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++++++ + f+p +++++++  +g i+ wd+++g+ll ++ +h+++v+ v f+ +++++v+g++D+ ikvw+++t  c+ tl+gh d++++++f+ 
   Q: 3    TKFETKSNRVKGLSFHPRRPWILASLHSGVIQMWDYRMGTLLDRFDEHDGPVRGVHFHATQPLFVSGGDDYKIKVWNYKTHRCLFTLTGHLDYIRTVQFHH 103
           67889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...........................ktgkllrtltgg 178
           +  ++vs+s+d+tir+w++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                             + + + l+g 
   Q: 104  EYPWIVSASDDQTIRIWNWQSRTCVA-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgalrkktvspaddilrltqmntdlfggVDAVVKYVLEG- 202
           **************************.*************************************************977777777776444444444466. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgd 277
           h++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+siriWd ++++ ++t+ +++++++  a+ +++ 
   Q: 203  HDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRIWDATKRTGIQTFRREHDRFWILAA-HPEM 302
           ********************************777668**********************************************************.6666 PP
   S: 278  nvlvlgsedskvniwklkknep 299
           n l++g  ds   ++kl++++p
   Q: 303  NLLAAG-HDSGMIVFKLERERP 323
           655555.689999999988765 PP

Organism

Aegilops tauschii

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPR RPWILASLHS GVIQMWDYRM GTLLDRFDEH DGPVRGVHFH 60
ATQPLFVSGG DDYKIKVWNY KTHRCLFTLT GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGACCA AGTTCGAGAC CAAGAGCAAC CGGGTCAAGG GCCTGAGCTT CCACCCGCGG 60
CGGCCATGGA TCCTCGCCAG CCTCCACAGC GGCGTGATCC AGATGTGGGA CTACCGCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

ats:F775_07673

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001758	Ailuropoda melanoleuca	53.85	0.00e+00	1346.00
IUUC-Atr-002493	Amborella trichopoda	79.41	0.00e+00	1966.00
IUUC-Aca-005154	Anolis carolinensis	78.43	8.00e-96	342.00
IUUC-Aly-006020	Arabidopsis lyrata	75.93	0.00e+00	1933.00
IUUC-Ath-007058	Arabidopsis thaliana	77.30	0.00e+00	1935.00
IUUC-Ago-007992	Ashbya gossypii	43.58	0.00e+00	993.00
IUUC-Acl-008027	Aspergillus clavatus	55.17	0.00e+00	971.00
IUUC-Afl-008644	Aspergillus flavus	55.91	0.00e+00	977.00
IUUC-Ani-009379	Aspergillus nidulans	55.58	0.00e+00	981.00
IUUC-Ang-009756	Aspergillus niger	47.53	0.00e+00	1140.00
IUUC-Aor-010174	Aspergillus oryzae	55.91	0.00e+00	977.00
IUUC-Ate-010302	Aspergillus terreus	47.83	0.00e+00	1162.00
IUUC-Ame-011229	Astyanax mexicanus	52.84	0.00e+00	1300.00
IUUC-Bgr-012300	Blumeria graminis	46.99	0.00e+00	1082.00
IUUC-Bta-012524	Bos taurus	54.32	0.00e+00	1343.00
IUUC-Bci-013781	Botrytis cinerea	46.53	0.00e+00	1121.00
IUUC-Bra-016978	Brassica rapa	76.33	0.00e+00	1919.00
IUUC-Cel-018115	Caenorhabditis elegans	54.93	0.00e+00	932.00
IUUC-Cja-019107	Callithrix jacchus	53.37	0.00e+00	1332.00
IUUC-Cfa-020675	Canis familiaris	53.51	0.00e+00	1319.00
IUUC-Cpo-021813	Cavia porcellus	54.41	0.00e+00	1356.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	69.47	0.00e+00	1242.00
IUUC-Csa-023523	Chlorocebus sabaeus	54.49	0.00e+00	1364.00
IUUC-Cin-025572	Ciona intestinalis	50.16	0.00e+00	1246.00
IUUC-Csv-025864	Ciona savignyi	56.43	0.00e+00	973.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	55.86	0.00e+00	987.00
IUUC-Cne-027053	Cryptococcus neoformans	49.80	0.00e+00	1173.00
IUUC-Dre-027421	Danio rerio	54.00	0.00e+00	1330.00
IUUC-Dno-029303	Dasypus novemcinctus	54.41	0.00e+00	1357.00
IUUC-Dor-030290	Dipodomys ordii	52.64	5.00e-165	574.00
IUUC-Dse-031543	Dothistroma septosporum	45.90	0.00e+00	1056.00
IUUC-Ete-032873	Echinops telfairi	52.57	0.00e+00	1200.00
IUUC-Eca-033773	Equus caballus	53.49	0.00e+00	1316.00
IUUC-Fca-035739	Felis catus	53.50	0.00e+00	1318.00
IUUC-Fal-037263	Ficedula albicollis	50.41	0.00e+00	1190.00
IUUC-Fox-037738	Fusarium oxysporum	47.69	0.00e+00	1129.00
IUUC-Fso-038153	Fusarium solani	47.12	0.00e+00	1124.00
IUUC-Gmo-039602	Gadus morhua	50.97	0.00e+00	1229.00
IUUC-Ggr-039931	Gaeumannomyces graminis	54.47	0.00e+00	969.00
IUUC-Gga-040590	Gallus gallus	53.39	0.00e+00	1346.00
IUUC-Gac-041318	Gasterosteus aculeatus	54.38	0.00e+00	1332.00
IUUC-Gma-043894	Glycine max	77.46	0.00e+00	1977.00
IUUC-Ggo-045029	Gorilla gorilla	54.01	0.00e+00	1355.00
IUUC-Hsa-046078	Homo sapiens	54.01	0.00e+00	1355.00
IUUC-Hvu-047316	Hordeum vulgare	98.65	0.00e+00	2304.00
IUUC-Kpa-049256	Komagataella pastoris	45.41	0.00e+00	1050.00
IUUC-Lch-049706	Latimeria chalumnae	54.28	0.00e+00	1337.00
IUUC-Lpe-051316	Leersia perrieri	93.60	0.00e+00	2277.00
IUUC-Loc-051867	Lepisosteus oculatus	50.12	0.00e+00	822.00
IUUC-Lma-053138	Leptosphaeria maculans	55.10	0.00e+00	999.00
IUUC-Laf-053510	Loxodonta africana	53.87	0.00e+00	1355.00
IUUC-Mcc-055836	Macaca mulatta	53.94	0.00e+00	1346.00
IUUC-Meu-056238	Macropus eugenii	56.36	0.00e+00	774.00
IUUC-Mor-057172	Magnaporthe oryzae	46.57	0.00e+00	1105.00
IUUC-Mpo-057300	Magnaporthe poae	46.66	0.00e+00	1094.00
IUUC-Mtr-058248	Medicago truncatula	76.97	0.00e+00	1961.00
IUUC-Mla-059019	Melampsora laricipopulina	49.08	0.00e+00	1200.00
IUUC-Mga-059499	Meleagris gallopavo	53.30	0.00e+00	1342.00
IUUC-Mvi-060336	Microbotryum violaceum	50.00	0.00e+00	1200.00
IUUC-Mmr-061102	Microcebus murinus	53.93	0.00e+00	1337.00
IUUC-Mdo-062594	Monodelphis domestica	54.57	0.00e+00	1377.00
IUUC-Mmu-063736	Mus musculus	53.69	0.00e+00	1341.00
IUUC-Mac-065272	Musa acuminata	73.54	0.00e+00	1843.00
IUUC-Mpu-066701	Mustela putorius furo	53.55	0.00e+00	1348.00
IUUC-Mlu-067392	Myotis lucifugus	53.77	0.00e+00	1343.00
IUUC-Nfi-068270	Neosartorya fischeri	55.53	0.00e+00	976.00
IUUC-Ncr-068892	Neurospora crassa	47.63	0.00e+00	1116.00
IUUC-Nle-069634	Nomascus leucogenys	65.42	0.00e+00	946.00
IUUC-Ont-072488	Oreochromis niloticus	53.75	0.00e+00	1316.00
IUUC-Ocu-074211	Oryctolagus cuniculus	54.32	0.00e+00	1354.00
IUUC-Oba-075761	Oryza barthii	92.77	0.00e+00	2299.00
IUUC-Obr-076429	Oryza brachyantha	91.63	0.00e+00	2279.00
IUUC-Ogl-077364	Oryza glaberrima	92.78	0.00e+00	2300.00
IUUC-Ogu-078257	Oryza glumaepatula	92.66	0.00e+00	2233.00
IUUC-Oin-079274	Oryza indica	92.61	0.00e+00	2296.00
IUUC-Olo-080466	Oryza longistaminata	96.45	0.00e+00	1659.00
IUUC-Oni-082874	Oryza nivara	92.61	0.00e+00	2295.00
IUUC-Opu-083885	Oryza punctata	94.33	0.00e+00	2308.00
IUUC-Oru-084274	Oryza rufipogon	92.69	0.00e+00	2299.00
IUUC-Osa-085565	Oryza sativa	92.69	0.00e+00	2299.00
IUUC-Ola-086921	Oryzias latipes	53.49	0.00e+00	1315.00
IUUC-Olu-087639	Ostreococcus lucimarinus	60.52	0.00e+00	1522.00
IUUC-Oga-087991	Otolemur garnettii	51.57	0.00e+00	1261.00
IUUC-Oar-089590	Ovis aries	54.24	0.00e+00	1354.00
IUUC-Ptr-090808	Pan troglodytes	54.09	0.00e+00	1357.00
IUUC-Pan-092475	Papio anubis	54.20	0.00e+00	1355.00
IUUC-Psi-093044	Pelodiscus sinensis	54.25	0.00e+00	895.00
IUUC-Pno-094839	Phaeosphaeria nodorum	45.74	0.00e+00	1055.00
IUUC-Ppa-095390	Physcomitrella patens	68.41	0.00e+00	1719.00
IUUC-Pfo-097493	Poecilia formosa	54.16	0.00e+00	1323.00
IUUC-Pab-098497	Pongo abelii	54.41	0.00e+00	1363.00
IUUC-Pop-100086	Populus trichocarpa	79.36	0.00e+00	1993.00
IUUC-Pca-100413	Procavia capensis	60.25	0.00e+00	692.00
IUUC-Ppe-101392	Prunus persica	79.74	0.00e+00	2029.00
IUUC-Pva-102126	Pteropus vampyrus	51.93	0.00e+00	1279.00
IUUC-Pgr-103376	Puccinia graminis	49.68	0.00e+00	1215.00
IUUC-Ptt-103978	Puccinia triticina	44.47	0.00e+00	976.00
IUUC-Pte-104126	Pyrenophora teres	45.86	0.00e+00	1060.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	39.58	0.00e+00	736.00
IUUC-Rno-105428	Rattus norvegicus	54.12	0.00e+00	1349.00
IUUC-Sce-106464	Saccharomyces cerevisiae	42.86	0.00e+00	954.00
IUUC-Sha-107301	Sarcophilus harrisii	53.56	0.00e+00	1340.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	44.23	0.00e+00	1065.00
IUUC-Spo-108217	Schizosaccharomyces pombe	43.91	0.00e+00	1048.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	46.76	0.00e+00	1121.00
IUUC-Smo-109582	Selaginella moellendorffii	74.08	0.00e+00	1361.00
IUUC-Sit-109697	Setaria italica	91.47	0.00e+00	2280.00
IUUC-Sly-111447	Solanum lycopersicum	77.62	0.00e+00	1996.00
IUUC-Stu-112564	Solanum tuberosum	78.51	0.00e+00	2009.00
IUUC-Sbi-114388	Sorghum bicolor	91.79	0.00e+00	2281.00
IUUC-Sre-115209	Sporisorium reilianum	55.66	0.00e+00	1003.00
IUUC-Ssc-115933	Sus scrofa	54.32	0.00e+00	1356.00
IUUC-Tru-117772	Takifugu rubripes	54.01	0.00e+00	1304.00
IUUC-Tsy-119105	Tarsius syrichta	51.44	0.00e+00	1026.00
IUUC-Tni-120556	Tetraodon nigroviridis	41.77	0.00e+00	868.00
IUUC-Tre-121951	Trichoderma reesei	46.39	0.00e+00	1088.00
IUUC-Tvi-122359	Trichoderma virens	46.88	0.00e+00	1114.00
IUUC-Tae-123611	Triticum aestivum	99.92	0.00e+00	2393.00
IUUC-Tur-126754	Triticum urartu	97.86	0.00e+00	2338.00
IUUC-Tme-127170	Tuber melanosporum	47.85	0.00e+00	1182.00
IUUC-Tbe-127882	Tupaia belangeri	68.71	7.00e-129	454.00
IUUC-Ttr-128217	Tursiops truncatus	52.01	0.00e+00	1278.00
IUUC-Uma-129337	Ustilago maydis	55.78	0.00e+00	1001.00
IUUC-Vda-129828	Verticillium dahliae	46.63	0.00e+00	1117.00
IUUC-Vpa-130537	Vicugna pacos	53.59	0.00e+00	1326.00
IUUC-Vvi-130958	Vitis vinifera	79.25	0.00e+00	2007.00
IUUC-Xtr-132857	Xenopus tropicalis	52.07	0.00e+00	1259.00
IUUC-Xma-133138	Xiphophorus maculatus	54.16	0.00e+00	1325.00
IUUC-Yli-134399	Yarrowia lipolytica	49.02	0.00e+00	838.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence