iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026086

UUCD1 version

UUC-CiS-00479

Ensembl Protein ID

ENSCSAVP00000019811.1

UniProt Accession

H2ZQE5; H2ZQE5_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000011633.1	ENSCSAVT00000020023.1	ENSCSAVP00000019810.1
ENSCSAVG00000011633.1	ENSCSAVT00000020024.1	ENSCSAVP00000019811.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-74	250.8	1	627

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 12   mNSvLQcLsnipelrellle....kkkekln..eenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaq 93
           mNS++QcLsn+  l+e++      ++ ++++  ++++ ++kge+++ l++++++lw+ + ++  +++l+++++k+  +++g++q+D+q
   Q: 1    MNSIVQCLSNTDVLAEYFVLgqykNDLKNCRkdRSKKYGTKGEVIELLASVVRSLWTVTYSQDMTKSLKDSISKYGAQYKGSNQHDSQ 88
           9*****************998666333333300334478899********************************************** PP
   S: 94   EflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkee 181
           Ef+ +l+d+++e+l+         ++  +k++ ++  +   + + +s+i++lFqg+++s+++c++c+++s +++pfl +slp++++++
   Q: 89   EFMLWLFDKMHEDLN---------MQPVKKRSFTRRPSFPVDLSPTSFIQKLFQGHYRSSLTCPNCKKRSDTTDPFLCVSLPLKQRTT 167
           **************4.........4555555666667789999********************************************7 PP
   S: 182  tkke.................................................................................... 185
           +                                                                                       
   Q: 168  RP-Myanvvylpnkrrsgigrrhmagktikigvsvpldgkiidlrqavaaecgihsrllafvdlqhdgfhkaygddyslsdfpinnss 254
           64.46*********************************************************************************** PP
   S: 186  ........................................................................................ 185
                                                                                                   
   Q: 255  ttaanmslyafemppiakmtagtlprnfasshkkratlggkfgkegndatsatstvadsivvilinkqgvreqgkrfgrplvfrasrd 342
           **************************************************************************************** PP
   S: 186  ........................................................................................ 185
                                                                                                   
   Q: 343  vlstelqcmilnqmsdqlkngvkhermgslfrlqvkdgipnksylsqqaqqplrlptvdkalencpaggplhiklvaewdtdtkcgif 430
           **************************************************************************************** PP
   S: 186  ...........................slqdcLesftkeeelegenkyycekckkkqe.aekklklkklPevLilhLkRfsfseeqks 245
                                      +l++c++  t+ eel  +n++ c++ckk+q+ ++kkl+l +lP++L+lhLkRf  + + ++
   Q: 431  ekfpeekvevqdsvrlqkvlhqqpvtcTLEECFDLHTQVEELGADNAWLCPHCKKQQQgTVKKLSLLTLPDILVLHLKRF--RVTDGR 516
           ******************************************************9998689*******************..66779* PP
   S: 246  rekinkkvefple.Ldlspfctspeekqke...................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDs 312
           r+k+ ++vefp + L++ +++ + + ++ +                   ++ Y+L+av++H G+l+sGHY+a++ n  +gkW+lfdD+
   Q: 517  RTKLCTRVEFPVTgLNIGEMNGHISPQSPKsynwnpafashlpemvgpeDHLYDLYAVCNHFGNLNSGHYTACCSNpLNGKWYLFDDN 604
           ******************9999855555446677788888888888888***************************56777******* PP
   S: 313  kVtevkeeevleetgstaYvlfYkrr 338
           + + ++e++      ++ Y+lfY+rr
   Q: 605  HTEGITEDTLSP---QSVYILFYQRR 627
           **********99...*********96 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

MNSIVQCLSN TDVLAEYFVL GQYKNDLKNC RKDRSKKYGT KGEVIELLAS VVRSLWTVTY 60
SQDMTKSLKD SISKYGAQYK GSNQHDSQEF MLWLFDKMHE DLNMQPVKKR SFTRRPSFPV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTTTGATT TGAGTTCTAT TAACTCCATG CCTGGAGTCG TTGGGCTAAC AAACCACGAG 60
AAATACTTGT TTCATGAATT CCATTGTCCA ATGTCTAAGT AACACTGATG TTTTGGCGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001207	Ailuropoda melanoleuca	39.24	3.00e-134	471.00
IUUC-Apl-003186	Anas platyrhynchos	37.48	2.00e-115	409.00
IUUC-Aca-004949	Anolis carolinensis	37.16	3.00e-128	451.00
IUUC-Ame-010968	Astyanax mexicanus	37.96	3.00e-130	458.00
IUUC-Bta-013271	Bos taurus	38.88	1.00e-132	466.00
IUUC-Cja-018737	Callithrix jacchus	38.51	1.00e-118	419.00
IUUC-Cfa-021258	Canis familiaris	39.29	9.00e-134	469.00
IUUC-Csa-024188	Chlorocebus sabaeus	38.27	1.00e-133	469.00
IUUC-Cho-024813	Choloepus hoffmanni	33.77	3.00e-82	298.00
IUUC-Dre-028066	Danio rerio	37.91	2.00e-123	436.00
IUUC-Dno-029964	Dasypus novemcinctus	38.58	1.00e-115	409.00
IUUC-Dor-030475	Dipodomys ordii	39.36	5.00e-74	271.00
IUUC-Dme-032088	Drosophila melanogaster	34.09	4.00e-100	358.00
IUUC-Ete-032975	Echinops telfairi	34.56	3.00e-52	199.00
IUUC-Eca-034030	Equus caballus	39.33	3.00e-126	444.00
IUUC-Eeu-034629	Erinaceus europaeus	39.70	3.00e-27	115.00
IUUC-Fca-035788	Felis catus	38.90	5.00e-126	444.00
IUUC-Fal-036874	Ficedula albicollis	37.12	1.00e-113	402.00
IUUC-Gmo-039479	Gadus morhua	38.66	2.00e-133	468.00
IUUC-Gga-041092	Gallus gallus	37.67	1.00e-128	452.00
IUUC-Gac-041609	Gasterosteus aculeatus	38.20	2.00e-132	465.00
IUUC-Ggo-045171	Gorilla gorilla	39.54	2.00e-119	422.00
IUUC-Hsa-046805	Homo sapiens	38.61	2.00e-133	468.00
IUUC-Hvu-047686	Hordeum vulgare	26.62	5.00e-37	147.00
IUUC-Itr-048158	Ictidomys tridecemlineatus	38.91	3.00e-119	421.00
IUUC-Lch-050332	Latimeria chalumnae	36.38	3.00e-123	434.00
IUUC-Loc-052852	Lepisosteus oculatus	38.61	5.00e-130	457.00
IUUC-Laf-054033	Loxodonta africana	38.60	9.00e-120	423.00
IUUC-Mcc-055398	Macaca mulatta	38.13	2.00e-133	469.00
IUUC-Meu-056822	Macropus eugenii	32.94	5.00e-87	314.00
IUUC-Mga-060115	Meleagris gallopavo	37.50	5.00e-114	404.00
IUUC-Mmr-061150	Microcebus murinus	38.43	1.00e-133	469.00
IUUC-Mdo-062700	Monodelphis domestica	38.66	6.00e-135	474.00
IUUC-Mmu-063512	Mus musculus	38.55	8.00e-135	473.00
IUUC-Mpu-066307	Mustela putorius furo	36.83	1.00e-114	405.00
IUUC-Mlu-067870	Myotis lucifugus	38.49	6.00e-129	453.00
IUUC-Nle-069898	Nomascus leucogenys	38.61	5.00e-134	470.00
IUUC-Opr-070499	Ochotona princeps	38.98	8.00e-121	426.00
IUUC-Ont-072469	Oreochromis niloticus	38.47	2.00e-130	459.00
IUUC-Oan-073175	Ornithorhynchus anatinus	38.60	2.00e-119	422.00
IUUC-Ocu-074014	Oryctolagus cuniculus	38.58	3.00e-107	380.00
IUUC-Ola-087303	Oryzias latipes	39.08	2.00e-129	455.00
IUUC-Oga-089021	Otolemur garnettii	39.43	5.00e-136	477.00
IUUC-Oar-090016	Ovis aries	38.88	3.00e-132	464.00
IUUC-Ptr-090864	Pan troglodytes	39.18	7.00e-134	470.00
IUUC-Pan-092370	Papio anubis	38.13	1.00e-133	469.00
IUUC-Psi-093881	Pelodiscus sinensis	38.22	2.00e-120	425.00
IUUC-Pfo-097427	Poecilia formosa	37.55	6.00e-132	464.00
IUUC-Pab-098104	Pongo abelii	37.57	1.00e-124	439.00
IUUC-Pca-100640	Procavia capensis	39.32	1.00e-45	176.00
IUUC-Pva-102287	Pteropus vampyrus	38.45	3.00e-112	398.00
IUUC-Rno-106033	Rattus norvegicus	39.37	2.00e-134	472.00
IUUC-Sha-107041	Sarcophilus harrisii	39.21	1.00e-121	429.00
IUUC-Sar-113105	Sorex araneus	35.19	8.00e-82	296.00
IUUC-Ssc-115312	Sus scrofa	38.98	4.00e-120	424.00
IUUC-Tgu-116889	Taeniopygia guttata	36.97	7.00e-114	403.00
IUUC-Tru-118340	Takifugu rubripes	38.12	9.00e-132	463.00
IUUC-Tsy-118887	Tarsius syrichta	34.12	1.00e-101	363.00
IUUC-Tni-120463	Tetraodon nigroviridis	38.66	5.00e-134	471.00
IUUC-Ttr-128210	Tursiops truncatus	39.91	1.00e-132	466.00
IUUC-Vpa-130222	Vicugna pacos	35.23	5.00e-42	164.00
IUUC-Xtr-132509	Xenopus tropicalis	38.50	2.00e-130	458.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence