iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000022502.3	ENSMMUT00000064440.1	ENSMMUP00000052616.1
ENSMMUG00000022502.3	ENSMMUT00000031641.2	ENSMMUP00000029601.2
ENSMMUG00000022502.3	ENSMMUT00000031642.2	ENSMMUP00000029602.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-08	35.4	12	53
E3 activity/RING/U-box	8.40e-08	33.3	7	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle f+d p++  CgH f++ Cl   w        + f CP Cr
   Q: 12   CPICLEYFQD-PVSIECGHNFCRGCLhRSW----APGGGPFPCPECR 53
           **********.***************9999....7799********8 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk..tcPvtrqplteedlvPnltlrrliqawc 69
            ee+ CpI le ++dPv +++G+ + r ++++  a gg    cP +r+p ++  l Pn +l rl ++ +
   Q: 7    QEELTCPICLEYFQDPVSIECGHNFCRGCLHRSWAPGGGpfPCPECRHPSAPAALRPNWALARLTEKTR 75
           6899**************************98555555559********************99988765 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MEAEDLQEEL TCPICLEYFQ DPVSIECGHN FCRGCLHRSW APGGGPFPCP ECRHPSAPAA 60
LRPNWALARL TEKTRRRRLG PVPPGLCSRH WEPLRLFCED DQRPVCLVCR ESQEHQTHAM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCGCGCTC AGGCCGGGCA ATGTGCGCGT TCCTTTTGGG TCCTGAACCC CGGAAGAGAC 60
ACTGCGCAGT ACCCTCTTAC GTGAGGCCGT GGCGGTTTTT CGGAAGTCGT CTGGTCTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:0008270--F:zinc ion binding
GO:0070206--P:protein trimerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002308	Ailuropoda melanoleuca	63.82	5.00e-160	557.00
IUUC-Cel-018621	Caenorhabditis elegans	36.26	9.00e-09	54.70
IUUC-Cja-019204	Callithrix jacchus	84.40	0.00e+00	834.00
IUUC-Cfa-021283	Canis familiaris	74.85	0.00e+00	724.00
IUUC-Csa-023476	Chlorocebus sabaeus	95.93	0.00e+00	917.00
IUUC-Cho-024657	Choloepus hoffmanni	63.21	7.00e-161	560.00
IUUC-Cne-027043	Cryptococcus neoformans	44.74	3.00e-06	46.60
IUUC-Eca-033740	Equus caballus	77.03	4.00e-157	547.00
IUUC-Hsa-046707	Homo sapiens	94.20	0.00e+00	937.00
IUUC-Mmr-061318	Microcebus murinus	75.86	0.00e+00	755.00
IUUC-Mpu-066377	Mustela putorius furo	72.21	0.00e+00	680.00
IUUC-Mlu-067319	Myotis lucifugus	73.60	9.00e-145	506.00
IUUC-Nle-069382	Nomascus leucogenys	92.90	0.00e+00	647.00
IUUC-Opr-070278	Ochotona princeps	64.93	2.00e-173	602.00
IUUC-Oga-088830	Otolemur garnettii	66.73	2.00e-158	551.00
IUUC-Oar-089188	Ovis aries	72.01	0.00e+00	694.00
IUUC-Pan-092332	Papio anubis	96.57	0.00e+00	941.00
IUUC-Pab-097648	Pongo abelii	92.48	0.00e+00	897.00
IUUC-Pva-102131	Pteropus vampyrus	73.09	0.00e+00	716.00
IUUC-Ssc-116309	Sus scrofa	67.06	8.00e-174	603.00
IUUC-Tsy-119365	Tarsius syrichta	73.49	1.00e-133	469.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence