iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089249

Ensembl Protein ID

ENSOARP00000015531.1

UniProt Accession

W5PYJ7; W5PYJ7_SHEEP

Genbank Protein ID

ENSOARP00000015531

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01045898

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000014470.1	ENSOART00000015758.1	ENSOARP00000015531.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-16	58.5	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 51   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 80
           8***********777*************** PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MRAVLTWRDK VEQCVYDLAF KPDGAQLIVA AGSRLLVYDT SDGTLLQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY THNDSIQCVS YNPVTHQLAS CSSSDIGLWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGGCCG TGTTGACGTG GAGAGATAAA GTCGAACAGT GGTGAGGAGC GGGGCTGTCC 60
GGGAGGAGCG GGAGGCCGAG GGCCAGCAGG GATGGCGGGC GCCTTGGCGT GTATCCCGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

KEGG

oas:101123504

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	90.19	0.00e+00	2230.00
IUUC-Apl-003504	Anas platyrhynchos	89.10	0.00e+00	2160.00
IUUC-Aca-004767	Anolis carolinensis	82.70	0.00e+00	2093.00
IUUC-Ame-011642	Astyanax mexicanus	71.49	0.00e+00	1759.00
IUUC-Bta-012969	Bos taurus	98.59	0.00e+00	1982.00
IUUC-Cel-018670	Caenorhabditis elegans	38.47	0.00e+00	892.00
IUUC-Cja-019249	Callithrix jacchus	80.37	0.00e+00	1929.00
IUUC-Cfa-020915	Canis familiaris	95.67	0.00e+00	1922.00
IUUC-Cpo-021888	Cavia porcellus	89.83	0.00e+00	2202.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	51.15	0.00e+00	1152.00
IUUC-Csa-023533	Chlorocebus sabaeus	91.05	0.00e+00	1831.00
IUUC-Cin-025121	Ciona intestinalis	61.17	0.00e+00	1541.00
IUUC-Csv-026240	Ciona savignyi	58.76	0.00e+00	1433.00
IUUC-Dno-029685	Dasypus novemcinctus	95.35	0.00e+00	2281.00
IUUC-Dme-032005	Drosophila melanogaster	25.52	1.00e-07	52.80
IUUC-Ete-032682	Echinops telfairi	84.49	0.00e+00	1686.00
IUUC-Eca-033831	Equus caballus	90.89	0.00e+00	2287.00
IUUC-Eeu-034919	Erinaceus europaeus	86.31	0.00e+00	1028.00
IUUC-Fca-036559	Felis catus	88.48	0.00e+00	2178.00
IUUC-Fal-037340	Ficedula albicollis	87.06	0.00e+00	2110.00
IUUC-Gga-040595	Gallus gallus	88.08	0.00e+00	2163.00
IUUC-Ggo-045356	Gorilla gorilla	77.85	0.00e+00	1898.00
IUUC-Hsa-046135	Homo sapiens	77.73	0.00e+00	1897.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	81.42	0.00e+00	1756.00
IUUC-Lch-050183	Latimeria chalumnae	82.21	0.00e+00	1177.00
IUUC-Loc-052049	Lepisosteus oculatus	84.79	0.00e+00	2083.00
IUUC-Laf-053728	Loxodonta africana	88.66	0.00e+00	2178.00
IUUC-Mcc-054971	Macaca mulatta	79.97	0.00e+00	1969.00
IUUC-Meu-056446	Macropus eugenii	80.70	0.00e+00	2071.00
IUUC-Mga-059296	Meleagris gallopavo	87.46	0.00e+00	1796.00
IUUC-Mmr-061232	Microcebus murinus	82.26	0.00e+00	2003.00
IUUC-Mdo-062115	Monodelphis domestica	88.16	0.00e+00	2221.00
IUUC-Mmu-063664	Mus musculus	88.56	0.00e+00	2236.00
IUUC-Mpu-066136	Mustela putorius furo	91.03	0.00e+00	1845.00
IUUC-Mlu-068238	Myotis lucifugus	92.45	0.00e+00	1909.00
IUUC-Nle-069003	Nomascus leucogenys	79.26	0.00e+00	1886.00
IUUC-Ont-072080	Oreochromis niloticus	74.32	0.00e+00	1892.00
IUUC-Oan-072891	Ornithorhynchus anatinus	92.11	0.00e+00	941.00
IUUC-Ocu-074262	Oryctolagus cuniculus	85.91	0.00e+00	2077.00
IUUC-Ola-086538	Oryzias latipes	75.35	0.00e+00	1539.00
IUUC-Oga-088722	Otolemur garnettii	94.86	0.00e+00	1891.00
IUUC-Ptr-090752	Pan troglodytes	90.44	0.00e+00	1815.00
IUUC-Pan-092472	Papio anubis	82.70	0.00e+00	1987.00
IUUC-Psi-093335	Pelodiscus sinensis	90.11	0.00e+00	2210.00
IUUC-Pma-094520	Petromyzon marinus	71.56	0.00e+00	1634.00
IUUC-Ppa-095600	Physcomitrella patens	63.72	9.00e-41	158.00
IUUC-Pfo-096526	Poecilia formosa	69.28	0.00e+00	1711.00
IUUC-Pab-098428	Pongo abelii	88.16	0.00e+00	1094.00
IUUC-Pca-100233	Procavia capensis	85.65	0.00e+00	755.00
IUUC-Pva-103064	Pteropus vampyrus	77.22	0.00e+00	1888.00
IUUC-Rno-105764	Rattus norvegicus	88.40	0.00e+00	2188.00
IUUC-Sha-106649	Sarcophilus harrisii	87.57	0.00e+00	2189.00
IUUC-Smo-109478	Selaginella moellendorffii	41.93	0.00e+00	922.00
IUUC-Tgu-116870	Taeniopygia guttata	83.35	0.00e+00	2026.00
IUUC-Tru-118661	Takifugu rubripes	69.04	0.00e+00	1732.00
IUUC-Tsy-119640	Tarsius syrichta	75.52	0.00e+00	654.00
IUUC-Tni-120812	Tetraodon nigroviridis	64.30	0.00e+00	1540.00
IUUC-Ttr-128862	Tursiops truncatus	94.37	0.00e+00	1944.00
IUUC-Vpa-130049	Vicugna pacos	79.47	1.00e-153	537.00
IUUC-Xtr-131914	Xenopus tropicalis	82.34	0.00e+00	2001.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence