iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088593

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03000873

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000013098.2	ENSOGAT00000013102.2	ENSOGAP00000011735.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.10e-82	276.5	448	868

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+ +l+     l e+    ++++l+++lq lf+ l +s++ a+sp+++l+a +   + fs   qq
   Q: 448  GLINLGNTCYVNSILQALFMASDFRHSVLR-----LTEN----NSQPLMTKLQWLFAFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 525
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++  + +e++++ +++ ++++F+g++ s+i cl c nvssree f+dlsl++p  
   Q: 526  DCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSLPSPPEEPPSPSSTAVEKMFGGKIVSRICCLCCLNVSSREEAFTDLSLAFPPP 609
           *****************.....667777777777778888999********************************************99 PP
   S: 180  eetkke................................................................................... 185
           e +  +                                                                                   
   Q: 610  ERCRRRrvgsvmlpaedirirelppvaqakvpsprvgsqrqrkhcitgdtptivldiegldskgaegessrveeeeraeedkeqtsgpe 698
           9887779********************************************************************************** PP
   S: 186  ...slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeek 271
              s+ d+ + f ++e+l+ en+yyce+c ++q+aek ++l++ P++Lil L Rfsf+ ++++r+ki + v +pl L l     +    
   Q: 699  gsrSVLDLVNYFLSPERLTAENRYYCESCASLQDAEKVVELSQGPRYLILTLLRFSFDLRTMRRRKILDDVAIPLLLRLPLAGGR---- 783
           **************************************************************************99999855555.... PP
   S: 272  qkekkkYeLiavvvHsG.slssGHYvayvkn................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
               + Y+L++vvvHsG s++sGHY++y+++                 +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 784  ---GQAYDLCSVVVHSGvSSESGHYYCYAREgaarpapslgtadrpePENQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 868
           ...89**************************99999999999999888999*******************999************985 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MDKILEAVVT SSYPASVKQG LVRRVLEAAR QPLEREQCLA LLALGARLYV GGADELPRRV 60
GCQLLHVAGR HHPDVFAEFF SARRVLRLLQ GGAGPPGARA LACVQLGLQL LPEGPAADEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGC GGTCGTGACG TCGTCCTACC CGGCCAGCGT GAAGCAAGGG 60
CTGGTGCGGC GCGTGCTGGA GGCGGCGCGG CAACCGCTGG AGCGGGAGCA GTGCCTGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	87.95	0.00e+00	957.00
IUUC-Apl-004121	Anas platyrhynchos	64.07	0.00e+00	1103.00
IUUC-Aca-005070	Anolis carolinensis	62.28	0.00e+00	780.00
IUUC-Bta-012545	Bos taurus	90.98	0.00e+00	1142.00
IUUC-Cja-019731	Callithrix jacchus	94.07	0.00e+00	1152.00
IUUC-Cfa-020095	Canis familiaris	94.50	0.00e+00	1169.00
IUUC-Cpo-021961	Cavia porcellus	91.11	0.00e+00	1312.00
IUUC-Csa-023167	Chlorocebus sabaeus	89.17	0.00e+00	1433.00
IUUC-Cin-025604	Ciona intestinalis	31.85	1.00e-39	157.00
IUUC-Dno-029186	Dasypus novemcinctus	81.82	0.00e+00	815.00
IUUC-Dor-030538	Dipodomys ordii	97.77	0.00e+00	978.00
IUUC-Ete-032512	Echinops telfairi	90.51	3.00e-107	382.00
IUUC-Eca-033279	Equus caballus	95.77	0.00e+00	901.00
IUUC-Eeu-035120	Erinaceus europaeus	71.17	0.00e+00	813.00
IUUC-Fca-035969	Felis catus	93.25	0.00e+00	895.00
IUUC-Fal-037625	Ficedula albicollis	64.31	0.00e+00	1120.00
IUUC-Gga-040767	Gallus gallus	64.50	0.00e+00	1140.00
IUUC-Ggo-045323	Gorilla gorilla	92.95	0.00e+00	917.00
IUUC-Hsa-046124	Homo sapiens	94.21	0.00e+00	1148.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	91.12	0.00e+00	1531.00
IUUC-Lch-049513	Latimeria chalumnae	58.04	0.00e+00	983.00
IUUC-Loc-052698	Lepisosteus oculatus	51.14	0.00e+00	877.00
IUUC-Laf-053999	Loxodonta africana	89.29	0.00e+00	1534.00
IUUC-Mcc-055266	Macaca mulatta	92.75	0.00e+00	1121.00
IUUC-Meu-056906	Macropus eugenii	73.93	0.00e+00	962.00
IUUC-Mga-059595	Meleagris gallopavo	63.69	0.00e+00	1120.00
IUUC-Mmr-061720	Microcebus murinus	94.49	0.00e+00	722.00
IUUC-Mdo-062167	Monodelphis domestica	72.78	0.00e+00	1288.00
IUUC-Mmu-063298	Mus musculus	91.99	0.00e+00	1142.00
IUUC-Mpu-066195	Mustela putorius furo	93.91	0.00e+00	1147.00
IUUC-Mlu-067583	Myotis lucifugus	91.44	0.00e+00	774.00
IUUC-Opr-070454	Ochotona princeps	89.49	2.00e-158	553.00
IUUC-Ocu-074121	Oryctolagus cuniculus	85.53	0.00e+00	940.00
IUUC-Oar-090140	Ovis aries	90.68	0.00e+00	1130.00
IUUC-Pan-092168	Papio anubis	89.27	0.00e+00	1434.00
IUUC-Psi-093707	Pelodiscus sinensis	64.98	0.00e+00	1145.00
IUUC-Pab-097614	Pongo abelii	93.62	0.00e+00	1138.00
IUUC-Pca-100683	Procavia capensis	87.96	0.00e+00	1107.00
IUUC-Pva-103146	Pteropus vampyrus	80.24	0.00e+00	1014.00
IUUC-Rno-105061	Rattus norvegicus	92.42	0.00e+00	1149.00
IUUC-Sha-106686	Sarcophilus harrisii	72.16	0.00e+00	948.00
IUUC-Tgu-117024	Taeniopygia guttata	66.24	0.00e+00	1152.00
IUUC-Tsy-119505	Tarsius syrichta	80.70	3.00e-164	572.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence