iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013129

Ensembl Protein ID

ENSBTAP00000023877.5

UniProt Accession

E1BFN3; E1BFN3_BOVIN

Genbank Protein ID

ENSBTAP00000023877

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02026720

Gene Name

AHI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000017958.5	ENSBTAT00000023877.5	ENSBTAP00000023877.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-20	72.4	652	682
UBD/SH3	2.90e-14	52.9	1054	1106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gH + +++l++  +d++++++s Dgt ++W+
   Q: 652  GHLNIIYDLCWskDDRYILTASSDGTARIWR 682
           79999*******666***************8 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v +lydy+a+ +deLt+++Gd+++v    + +e+W++g +  +g++G fP+n v+
   Q: 1054 TVVALYDYTANRSDELTIHRGDIIRVF--FKDNEDWWYG-SIGKGQEGYFPANHVA 1106
           689***********************9..8999******.799**********996 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MPTVESEAKV KTKVRFEELL KAHNDLRRER KKLKKKIAQP GEKISMDVMY RDLYYLPDKR 60
TSLNLDAVTS NLQKIRETKS DDITAANTKN PEKNMRVIKN KPRDPQSATE DPENDVIVEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCACTG GTAAGATTTC TATGAAATTT TTTATATGCA GTGCATGTTA TTTACTTTAA 60
AGTTTGGATT ATTTTAAGGG ATTCTTTAAC CAATTAAGGA GTAAAGTAGA TATCATCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001452--SH3_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50002--SH3
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00018--SH3_1
PF00400--WD40

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3
SM00320--WD40

Gene Ontology

GO:0005912--C:adherens junction
GO:0005911--C:cell-cell junction
GO:0005814--C:centriole
GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0005929--C:cilium
GO:0097730--C:non-motile cilium
GO:0034613--P:cellular protein localization
GO:0007417--P:central nervous system development
GO:0060271--P:cilium assembly
GO:0035844--P:cloaca development
GO:0001947--P:heart looping
GO:0030902--P:hindbrain development
GO:0070121--P:Kupffer's vesicle development
GO:0070986--P:left/right axis specification
GO:0001738--P:morphogenesis of a polarized epithelium
GO:0043066--P:negative regulation of apoptotic process
GO:0071599--P:otic vesicle development
GO:0035845--P:photoreceptor cell outer segment organization
GO:0030862--P:positive regulation of polarized epithelial cell differentiation
GO:0002092--P:positive regulation of receptor internalization
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0039023--P:pronephric duct morphogenesis
GO:0039008--P:pronephric nephron tubule morphogenesis
GO:0050795--P:regulation of behavior
GO:0010842--P:retina layer formation
GO:0065001--P:specification of axis polarity
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001943	Ailuropoda melanoleuca	84.87	0.00e+00	1676.00
IUUC-Apl-004057	Anas platyrhynchos	50.30	0.00e+00	1055.00
IUUC-Aca-004306	Anolis carolinensis	50.59	0.00e+00	880.00
IUUC-Ame-010981	Astyanax mexicanus	57.21	0.00e+00	786.00
IUUC-Cja-018979	Callithrix jacchus	78.17	0.00e+00	1542.00
IUUC-Cfa-020121	Canis familiaris	85.25	0.00e+00	1857.00
IUUC-Cpo-022219	Cavia porcellus	77.88	0.00e+00	1305.00
IUUC-Csa-023991	Chlorocebus sabaeus	82.97	0.00e+00	1838.00
IUUC-Cho-024782	Choloepus hoffmanni	78.62	0.00e+00	974.00
IUUC-Cin-025149	Ciona intestinalis	40.10	3.00e-167	582.00
IUUC-Csv-026188	Ciona savignyi	38.89	6.00e-124	437.00
IUUC-Dre-028737	Danio rerio	51.21	0.00e+00	854.00
IUUC-Dno-029756	Dasypus novemcinctus	80.84	0.00e+00	1734.00
IUUC-Dor-030821	Dipodomys ordii	69.57	0.00e+00	1424.00
IUUC-Ete-032237	Echinops telfairi	80.35	0.00e+00	1583.00
IUUC-Eca-033491	Equus caballus	86.64	0.00e+00	1895.00
IUUC-Eeu-034812	Erinaceus europaeus	74.50	0.00e+00	927.00
IUUC-Fca-035868	Felis catus	85.52	0.00e+00	1739.00
IUUC-Fal-037571	Ficedula albicollis	55.92	0.00e+00	804.00
IUUC-Gmo-039358	Gadus morhua	51.42	0.00e+00	798.00
IUUC-Gga-040233	Gallus gallus	55.32	0.00e+00	978.00
IUUC-Gac-041744	Gasterosteus aculeatus	49.32	0.00e+00	798.00
IUUC-Ggo-044766	Gorilla gorilla	82.27	0.00e+00	1833.00
IUUC-Hsa-046660	Homo sapiens	82.27	0.00e+00	1837.00
IUUC-Itr-048282	Ictidomys tridecemlineatus	84.39	0.00e+00	1820.00
IUUC-Loc-052658	Lepisosteus oculatus	47.86	0.00e+00	855.00
IUUC-Laf-053564	Loxodonta africana	87.25	0.00e+00	1482.00
IUUC-Mcc-055480	Macaca mulatta	82.79	0.00e+00	1848.00
IUUC-Meu-056362	Macropus eugenii	58.28	0.00e+00	814.00
IUUC-Mga-060033	Meleagris gallopavo	50.47	0.00e+00	1077.00
IUUC-Mmr-061075	Microcebus murinus	83.73	0.00e+00	1848.00
IUUC-Mdo-062818	Monodelphis domestica	55.07	0.00e+00	1172.00
IUUC-Mmu-063987	Mus musculus	79.47	0.00e+00	1540.00
IUUC-Mpu-066242	Mustela putorius furo	81.56	0.00e+00	1729.00
IUUC-Mlu-067123	Myotis lucifugus	80.19	0.00e+00	1734.00
IUUC-Nle-069793	Nomascus leucogenys	82.18	0.00e+00	1838.00
IUUC-Opr-071110	Ochotona princeps	73.74	0.00e+00	881.00
IUUC-Ont-072179	Oreochromis niloticus	54.61	0.00e+00	761.00
IUUC-Oan-073201	Ornithorhynchus anatinus	64.91	6.00e-139	486.00
IUUC-Ocu-074224	Oryctolagus cuniculus	82.06	0.00e+00	1869.00
IUUC-Ola-086818	Oryzias latipes	53.70	3.00e-72	264.00
IUUC-Oga-088338	Otolemur garnettii	84.48	0.00e+00	1743.00
IUUC-Oar-089247	Ovis aries	92.21	0.00e+00	2049.00
IUUC-Ptr-090830	Pan troglodytes	82.62	0.00e+00	1843.00
IUUC-Pan-092469	Papio anubis	82.79	0.00e+00	1848.00
IUUC-Psi-093183	Pelodiscus sinensis	50.46	0.00e+00	1055.00
IUUC-Pma-094415	Petromyzon marinus	47.50	3.00e-158	551.00
IUUC-Pfo-096577	Poecilia formosa	55.10	0.00e+00	770.00
IUUC-Pab-098236	Pongo abelii	80.25	0.00e+00	1602.00
IUUC-Pca-100560	Procavia capensis	67.66	0.00e+00	1399.00
IUUC-Pva-102565	Pteropus vampyrus	76.98	0.00e+00	1338.00
IUUC-Rno-104881	Rattus norvegicus	78.87	0.00e+00	1555.00
IUUC-Sha-106577	Sarcophilus harrisii	65.74	1.00e-164	572.00
IUUC-Sar-113265	Sorex araneus	72.55	0.00e+00	1488.00
IUUC-Ssc-116174	Sus scrofa	88.64	0.00e+00	1920.00
IUUC-Tgu-116618	Taeniopygia guttata	48.89	0.00e+00	898.00
IUUC-Tru-117761	Takifugu rubripes	43.56	0.00e+00	671.00
IUUC-Tsy-119557	Tarsius syrichta	76.78	0.00e+00	928.00
IUUC-Tni-119782	Tetraodon nigroviridis	50.70	0.00e+00	809.00
IUUC-Tbe-127529	Tupaia belangeri	68.91	1.00e-119	424.00
IUUC-Ttr-128444	Tursiops truncatus	85.30	0.00e+00	1864.00
IUUC-Vpa-130337	Vicugna pacos	77.87	0.00e+00	1628.00
IUUC-Xtr-132055	Xenopus tropicalis	57.86	0.00e+00	748.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence