iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012659

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02073086

Gene Name

USP27X

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000039391.2	ENSBTAT00000056161.2	ENSBTAP00000049108.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.10e-91	305.0	79	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ ++++++    ++p+ +l++++ +lf+el++++ +   p +ll+ ++  a+++ gy+qq
   Q: 79   GLINLGNTCFMNCIVQALTHTPILRDFFLS-DRHRCEM---PSPELCLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQ 163
           9*****************************.9999987...589********************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl   ld l++++k                  +  +  +++++ +++i+++F g l+s+++c++c+ vs++ +p +d+sl++pg+
   Q: 164  DAHEFLIAALDVLHRHCKG----------------DDAGKAASNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGS 236
           *****************22................22335678899999***************************************9 PP
   S: 180  eetkke...................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksreki 249
            ++  +                   +l+dcL+ ft++e+l ++ k++c +c+++qe++k+l+++klP v ++h+kRf  +++ k+r+ki
   Q: 237  CTSFWPmspgressvngeshipgitTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRF--EHSAKQRRKI 323
           98766699*********************************************************************..55667999** PP
   S: 250  nkkvefpleLdlspfctspeekqke............kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleet 326
           +++++fpleLd++pf++s++e+  +            ++kY+L+avv+H+G+l+sGHY+++++++k++W+++dD  +t+ + ++vl   
   Q: 324  TTYISFPLELDMTPFMASSKESRMNgqlqlptnsgndENKYSLFAVVNHQGTLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLD-- 410
           ******************5544444566666666666**************************************************.. PP
   S: 327  gstaYvlfYkrr 338
            s++Y+lfY+++
   Q: 411  -SEGYLLFYHKQ 421
           .********985 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MCKDYVYDRD IEQIAKEEQG EALKLQASTS TEVSHQQYSV PGLGEKYPTW ETTKPELELL 60
GHNPRRRRIA SSFTIGLRGL INLGNTCFMN CIVQALTHTP ILRDFFLSDR HRCEMPSPEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGACGGCG GAGAAGGCGG AGAGGAAGGT GGAGGCAGAG GCGAAGGTGG AAGGGAAGGT 60
AGAGGCGGCG GGGAAGGTGG AGGCGGCTGG GAAGGTGGAC GCCACCGGGA AGGTGGAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0043065--P:positive regulation of apoptotic process
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

bta:781718

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cfa-020956	Canis familiaris	98.17	0.00e+00	899.00
IUUC-Csa-023350	Chlorocebus sabaeus	97.95	0.00e+00	905.00
IUUC-Dno-029905	Dasypus novemcinctus	97.03	0.00e+00	895.00
IUUC-Dor-030832	Dipodomys ordii	97.41	9.00e-113	400.00
IUUC-Hsa-045775	Homo sapiens	98.17	0.00e+00	907.00
IUUC-Itr-048775	Ictidomys tridecemlineatus	98.17	0.00e+00	907.00
IUUC-Mmr-061013	Microcebus murinus	97.03	0.00e+00	898.00
IUUC-Mmu-064287	Mus musculus	96.12	0.00e+00	886.00
IUUC-Nle-069084	Nomascus leucogenys	98.17	0.00e+00	907.00
IUUC-Oga-088771	Otolemur garnettii	97.72	0.00e+00	900.00
IUUC-Oar-089610	Ovis aries	99.77	0.00e+00	915.00
IUUC-Pan-092253	Papio anubis	98.17	0.00e+00	902.00
IUUC-Ppa-095413	Physcomitrella patens	40.93	6.00e-79	288.00
IUUC-Pgr-103657	Puccinia graminis	29.31	3.00e-38	152.00
IUUC-Rno-105081	Rattus norvegicus	96.35	0.00e+00	891.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence