iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048775

Ensembl Protein ID

ENSSTOP00000017282.1

UniProt Accession

I3MYT6; I3MYT6_ICTTR

Genbank Protein ID

ENSSTOP00000017282

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01099254

Gene Name

USP27X

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000023186.1	ENSSTOT00000029701.1	ENSSTOP00000017282.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.10e-91	305.1	79	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ ++++++    ++p+ +l++++ +lf+el++++ +   p +ll+ ++  a+++ gy+qq
   Q: 79   GLINLGNTCFMNCIVQALTHTPILRDFFLS-DRHRCEM---PSPELCLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQ 163
           9*****************************.9999987...589********************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl   ld l++++k                  +  +  +++++ +++i+++F g l+s+++c++c+ vs++ +p +d+sl++pg+
   Q: 164  DAHEFLIAALDVLHRHCKG----------------DDVGKAANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGS 236
           *****************22................2344668899999****************************************9 PP
   S: 180  eetkke...................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksreki 249
            ++  +                   +l+dcL+ ft++e+l ++ k++c +c+++qe++k+l+++klP v ++h+kRf  +++ k+r+ki
   Q: 237  CTSFWPmspgrdssvngeshipgitTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRF--EHSAKQRRKI 323
           9876669**********************************************************************..55667999** PP
   S: 250  nkkvefpleLdlspfcts............peekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleet 326
           +++++fpleLd++pf++s            p+++ ++++kY+L+avv+H+G+l+sGHY+++++++k++W+++dD  +t+ + ++vl   
   Q: 324  TTYISFPLELDMTPFMASskesrmngqlqlPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLD-- 410
           ******************5555555555554444444**************************************************.. PP
   S: 327  gstaYvlfYkrr 338
            s++Y+lfY+++
   Q: 411  -SEGYLLFYHKQ 421
           .********985 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MCKDYVYDKD IEQIAKEEQG EALKLQASTS TEVSHQQCSV PGLGEKYPTW ETTKPELELL 60
GHNPRRRRIT SSFTIGLRGL INLGNTCFMN CIVQALTHTP ILRDFFLSDR HRCEMPSPEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCCGGTAC GGGAGGCGGA GCAGGAGCCG AAGGGGGAGC CGAAGCCGGA GCTGGAGGAT 60
GAGAATCCAA CGCGGAGCGG CGGTGGCGGC AGCAGCGACG AGGTTCCTCC CCCCACCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0043065--P:positive regulation of apoptotic process
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012659	Bos taurus	98.17	0.00e+00	907.00
IUUC-Cja-019954	Callithrix jacchus	89.27	0.00e+00	788.00
IUUC-Cfa-020956	Canis familiaris	98.63	0.00e+00	905.00
IUUC-Csa-023350	Chlorocebus sabaeus	99.32	0.00e+00	918.00
IUUC-Dno-029905	Dasypus novemcinctus	98.40	0.00e+00	909.00
IUUC-Dor-030832	Dipodomys ordii	97.41	7.00e-113	400.00
IUUC-Hsa-045775	Homo sapiens	99.54	0.00e+00	919.00
IUUC-Mmr-061013	Microcebus murinus	98.40	0.00e+00	910.00
IUUC-Mmu-064287	Mus musculus	96.35	0.00e+00	891.00
IUUC-Nle-069084	Nomascus leucogenys	99.54	0.00e+00	919.00
IUUC-Oga-088771	Otolemur garnettii	99.09	0.00e+00	911.00
IUUC-Oar-089610	Ovis aries	97.94	0.00e+00	901.00
IUUC-Pan-092253	Papio anubis	99.54	0.00e+00	914.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence