iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091975

Ensembl Protein ID

ENSPANP00000004949.1

UniProt Accession

A0A096MYD6; A0A096MYD6_PAPAN

Genbank Protein ID

ENSPANP00000004949

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01057390

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000008555.1	ENSPANT00000006567.1	ENSPANP00000004949.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	98.16	0.00e+00	873.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Papio anubis

Protein Sequence
(Fasta)

MTSFSTSAQC STSDSACRIS PGQINQVRPK LPLLKILHAA GAQGEMFTVK EVMHYLGQYI 60
MVKQLYDQQE QHMVYCGGDL LGELLGRQSF SVKDPSPLYD MLRKNLVTLA TATTDAAQTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTACCAAC AGACTGCAGT TTCTTCCCTG CCAAAATGAC ATCATTTTCC ACCTCTGCCC 60
AGTGTTCAAC ATCTGACAGT GCTTGCAGGA TCTCTCCTGG ACAAATCAAT CAGGTAAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	92.48	0.00e+00	804.00
IUUC-Apl-003800	Anas platyrhynchos	60.32	4.00e-154	537.00
IUUC-Aca-004608	Anolis carolinensis	57.23	4.00e-135	474.00
IUUC-Ame-010869	Astyanax mexicanus	46.54	2.00e-105	376.00
IUUC-Bta-013287	Bos taurus	89.61	0.00e+00	852.00
IUUC-Cja-019305	Callithrix jacchus	94.49	0.00e+00	850.00
IUUC-Cfa-020393	Canis familiaris	93.29	0.00e+00	825.00
IUUC-Cpo-022166	Cavia porcellus	89.48	0.00e+00	754.00
IUUC-Csa-023654	Chlorocebus sabaeus	99.39	0.00e+00	868.00
IUUC-Cho-024403	Choloepus hoffmanni	89.89	7.00e-129	453.00
IUUC-Dre-027754	Danio rerio	49.01	6.00e-116	410.00
IUUC-Dno-029630	Dasypus novemcinctus	88.82	0.00e+00	819.00
IUUC-Dor-031064	Dipodomys ordii	69.25	0.00e+00	643.00
IUUC-Ete-032901	Echinops telfairi	79.27	0.00e+00	754.00
IUUC-Eca-034234	Equus caballus	94.09	0.00e+00	899.00
IUUC-Eeu-035015	Erinaceus europaeus	65.04	3.00e-158	551.00
IUUC-Fca-036587	Felis catus	93.48	0.00e+00	841.00
IUUC-Fal-036906	Ficedula albicollis	53.77	8.00e-137	480.00
IUUC-Gmo-038646	Gadus morhua	44.16	2.00e-95	342.00
IUUC-Gga-040124	Gallus gallus	59.71	5.00e-114	403.00
IUUC-Gac-042397	Gasterosteus aculeatus	46.23	2.00e-105	375.00
IUUC-Ggo-045505	Gorilla gorilla	98.16	0.00e+00	882.00
IUUC-Hsa-046950	Homo sapiens	98.16	0.00e+00	882.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	91.04	0.00e+00	830.00
IUUC-Lch-050141	Latimeria chalumnae	54.69	5.00e-122	431.00
IUUC-Loc-051921	Lepisosteus oculatus	50.49	2.00e-115	409.00
IUUC-Laf-054281	Loxodonta africana	86.97	0.00e+00	778.00
IUUC-Mcc-055462	Macaca mulatta	95.93	0.00e+00	819.00
IUUC-Meu-056294	Macropus eugenii	70.86	3.00e-144	504.00
IUUC-Mga-059924	Meleagris gallopavo	60.65	2.00e-165	575.00
IUUC-Mmr-061428	Microcebus murinus	92.67	0.00e+00	869.00
IUUC-Mdo-062643	Monodelphis domestica	75.86	0.00e+00	716.00
IUUC-Mmu-063229	Mus musculus	83.30	0.00e+00	767.00
IUUC-Mpu-065782	Mustela putorius furo	90.87	0.00e+00	813.00
IUUC-Mlu-068105	Myotis lucifugus	80.28	0.00e+00	756.00
IUUC-Nle-069549	Nomascus leucogenys	98.57	0.00e+00	886.00
IUUC-Opr-070568	Ochotona princeps	90.75	0.00e+00	780.00
IUUC-Ont-072276	Oreochromis niloticus	46.71	9.00e-115	407.00
IUUC-Oan-072787	Ornithorhynchus anatinus	72.65	0.00e+00	642.00
IUUC-Ocu-074912	Oryctolagus cuniculus	90.22	0.00e+00	822.00
IUUC-Ola-087037	Oryzias latipes	44.85	6.00e-97	347.00
IUUC-Oga-088953	Otolemur garnettii	88.89	0.00e+00	812.00
IUUC-Oar-089202	Ovis aries	90.02	0.00e+00	859.00
IUUC-Ptr-090964	Pan troglodytes	98.16	0.00e+00	883.00
IUUC-Psi-093558	Pelodiscus sinensis	60.49	1.00e-156	546.00
IUUC-Pfo-096454	Poecilia formosa	46.22	2.00e-109	389.00
IUUC-Pab-098123	Pongo abelii	98.37	0.00e+00	887.00
IUUC-Pca-101112	Procavia capensis	78.46	0.00e+00	717.00
IUUC-Pva-103098	Pteropus vampyrus	82.08	0.00e+00	762.00
IUUC-Rno-105930	Rattus norvegicus	83.74	0.00e+00	740.00
IUUC-Sha-107512	Sarcophilus harrisii	74.19	0.00e+00	641.00
IUUC-Sar-113584	Sorex araneus	81.87	0.00e+00	711.00
IUUC-Tgu-116766	Taeniopygia guttata	56.70	1.00e-100	358.00
IUUC-Tru-117829	Takifugu rubripes	47.66	5.00e-112	397.00
IUUC-Tsy-119268	Tarsius syrichta	78.41	0.00e+00	680.00
IUUC-Tni-120204	Tetraodon nigroviridis	46.25	4.00e-108	384.00
IUUC-Tbe-127840	Tupaia belangeri	85.06	2.00e-126	445.00
IUUC-Ttr-128863	Tursiops truncatus	90.02	0.00e+00	829.00
IUUC-Vpa-130718	Vicugna pacos	92.69	0.00e+00	804.00
IUUC-Xtr-132320	Xenopus tropicalis	46.59	1.00e-88	320.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence