iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093333

Ensembl Protein ID

ENSPSIP00000009820.1

UniProt Accession

K7FP60; K7FP60_PELSI

Genbank Protein ID

ENSPSIP00000009820

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01163930

Gene Name

OTUD7B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000008867.1	ENSPSIT00000009869.1	ENSPSIP00000009820.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	2.00e-37	128.7	198	375

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek......edekefcqklvepe.......ak 76
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++ l++ + + +++++ k+++++++++++k      ++e++++ kl+++e         
   Q: 198  LPLATTGDGNCLLHAASLGMWGFHDRDLmLRKSLYTLMDKGVEREALKRRWRWQQTQQNKeteeewQKEWNELIKLASSEprmhygtN- 285
           6899************************************************************999************988877640. PP
   S: 77   g..................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYdaLva 137
           g                  ee+h+f+La++L+rp++vv++++l++         ++ggi+lpl++p++k +++p+vL+Y+++H++aLv+
   Q: 286  GgscgginvsakatmksllEEFHVFVLAHVLKRPVVVVADTMLRDsggeafapiPFGGIYLPLEVPANKcHRSPLVLAYDQAHFSALVS 374
           2566789999999**************************************************************************98 PP
   S: 138  l 138
           +
   Q: 375  M 375
           6 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

ALIYVPAVSN CLQGIHDHMT LDMDVVLSDF VRSTGAEPGL ARDLLEVSKL GKNWDVNAAL 60
SDFEQLRQVH AGNLPHSFNE GRTFKPLEKE AARPMRPPLQ RQDDLIQASE KRLSRGISHA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTTGATCT ATGTCCCAGC TGTTTCCAAC TGCCTGCAAG GAATTCATGA TCACATGACC 60
CTGGATATGG ATGTCGTCTT GTCGGATTTT GTTCGCTCAA CGGGGGCAGA GCCAGGACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0002385--P:mucosal immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032717--P:negative regulation of interleukin-8 production
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035871--P:protein K11-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002119	Ailuropoda melanoleuca	66.44	0.00e+00	1009.00
IUUC-Apl-003567	Anas platyrhynchos	78.88	0.00e+00	1197.00
IUUC-Bta-013398	Bos taurus	65.24	0.00e+00	981.00
IUUC-Cel-018468	Caenorhabditis elegans	48.00	3.00e-80	292.00
IUUC-Cja-019965	Callithrix jacchus	65.24	0.00e+00	993.00
IUUC-Cfa-020191	Canis familiaris	67.52	0.00e+00	1001.00
IUUC-Cpo-022232	Cavia porcellus	65.38	0.00e+00	949.00
IUUC-Csa-023593	Chlorocebus sabaeus	66.92	0.00e+00	1053.00
IUUC-Csv-026177	Ciona savignyi	33.90	2.00e-03	35.40
IUUC-Cgl-026461	Colletotrichum gloeosporioides	31.25	3.20e-02	33.10
IUUC-Dno-029900	Dasypus novemcinctus	65.22	0.00e+00	974.00
IUUC-Dor-031121	Dipodomys ordii	71.23	2.00e-168	585.00
IUUC-Ete-032473	Echinops telfairi	67.00	0.00e+00	823.00
IUUC-Eca-033946	Equus caballus	72.74	0.00e+00	831.00
IUUC-Eeu-034670	Erinaceus europaeus	63.98	0.00e+00	964.00
IUUC-Fca-035871	Felis catus	65.01	0.00e+00	957.00
IUUC-Gmo-039373	Gadus morhua	79.13	0.00e+00	689.00
IUUC-Gga-041105	Gallus gallus	82.06	0.00e+00	1309.00
IUUC-Gac-041806	Gasterosteus aculeatus	60.28	0.00e+00	877.00
IUUC-Ggo-045472	Gorilla gorilla	65.05	0.00e+00	1031.00
IUUC-Hsa-046473	Homo sapiens	65.38	0.00e+00	1023.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	67.12	0.00e+00	1008.00
IUUC-Lch-050432	Latimeria chalumnae	71.41	0.00e+00	1098.00
IUUC-Mcc-055261	Macaca mulatta	66.81	0.00e+00	1052.00
IUUC-Meu-056477	Macropus eugenii	64.73	0.00e+00	795.00
IUUC-Mga-059533	Meleagris gallopavo	79.89	0.00e+00	1236.00
IUUC-Mdo-062847	Monodelphis domestica	63.85	0.00e+00	974.00
IUUC-Mmu-064260	Mus musculus	64.79	0.00e+00	928.00
IUUC-Mpu-066876	Mustela putorius furo	63.19	0.00e+00	924.00
IUUC-Mlu-068039	Myotis lucifugus	65.13	0.00e+00	1008.00
IUUC-Nle-069260	Nomascus leucogenys	65.35	0.00e+00	1018.00
IUUC-Ont-071542	Oreochromis niloticus	80.17	0.00e+00	747.00
IUUC-Ola-086490	Oryzias latipes	78.31	0.00e+00	734.00
IUUC-Oga-088124	Otolemur garnettii	65.81	0.00e+00	986.00
IUUC-Oar-090086	Ovis aries	65.02	0.00e+00	975.00
IUUC-Ptr-091622	Pan troglodytes	73.29	0.00e+00	885.00
IUUC-Pan-092724	Papio anubis	66.70	0.00e+00	1043.00
IUUC-Pfo-096563	Poecilia formosa	79.57	0.00e+00	725.00
IUUC-Pab-098667	Pongo abelii	65.39	0.00e+00	1011.00
IUUC-Pva-102136	Pteropus vampyrus	64.27	0.00e+00	968.00
IUUC-Rno-105546	Rattus norvegicus	65.70	0.00e+00	962.00
IUUC-Sha-106732	Sarcophilus harrisii	65.41	0.00e+00	895.00
IUUC-Sar-113562	Sorex araneus	58.78	0.00e+00	809.00
IUUC-Ssc-116191	Sus scrofa	66.29	0.00e+00	996.00
IUUC-Tgu-116942	Taeniopygia guttata	83.89	0.00e+00	897.00
IUUC-Tru-117911	Takifugu rubripes	78.31	0.00e+00	725.00
IUUC-Tsy-119343	Tarsius syrichta	68.10	0.00e+00	879.00
IUUC-Tbe-127283	Tupaia belangeri	78.59	0.00e+00	655.00
IUUC-Ttr-128692	Tursiops truncatus	62.61	0.00e+00	913.00
IUUC-Xtr-132888	Xenopus tropicalis	71.00	0.00e+00	1099.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence