iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116942

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01060435

Gene Name

OTUD7B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000004479.1	ENSTGUT00000004665.1	ENSTGUP00000004616.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	4.90e-38	130.5	90	271

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++ l++ + + +++++ ++++++++++++k           ++e++++ kl+++e    
   Q: 90   LPLATTGDGNCLLHAASLGMWGFHDRDLmLRKSLYTLMEKGAEREALRRRWRWQQTQQNKesglvyteeewQKEWNELIKLASSEprvh 178
           6899*********************************************************************************9988 PP
   S: 75   ...akg.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYd 133
                g                 ee+h+f+La++L+rpi+vv++++l++         ++ggi+lpl++p++k +++p+vL+Y+++H++
   Q: 179  ystN-GgscggvesseepvyeslEEFHVFVLAHVLKRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPANKcHRSPLVLAYDQAHFS 266
           8540.357778****************************************************************************** PP
   S: 134  aLval 138
           aLv++
   Q: 267  ALVSM 271
           **986 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

EKRLSRGISH ASSTIVSLAR SHVSSNGSSS EHLLEMPICT FQLPDLTVYP EDFRSFIERD 60
LIEQSMLVAL EQAGRLNWWV TVDPSCQRLL PLATTGDGNC LLHAASLGMW GFHDRDLMLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAAGCGCC TGTCCCGGGG CATTTCCCAC GCCAGCTCCA CCATCGTGTC CCTGGCCCGT 60
TCCCATGTCT CCAGCAACGG CAGCAGCAGT GAGCACCTGC TGGAGATGCC CATCTGCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom

PROSITE

PS50802--OTU

Pfam

PF02338--OTU

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0002385--P:mucosal immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032717--P:negative regulation of interleukin-8 production
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035871--P:protein K11-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002119	Ailuropoda melanoleuca	75.04	0.00e+00	819.00
IUUC-Apl-003567	Anas platyrhynchos	91.39	0.00e+00	926.00
IUUC-Afl-008746	Aspergillus flavus	38.24	7.30e-01	28.50
IUUC-Aor-010224	Aspergillus oryzae	38.24	7.60e-01	28.50
IUUC-Bta-013398	Bos taurus	74.32	0.00e+00	798.00
IUUC-Cel-018468	Caenorhabditis elegans	50.84	7.00e-87	314.00
IUUC-Cja-019965	Callithrix jacchus	76.47	0.00e+00	839.00
IUUC-Cfa-020191	Canis familiaris	76.56	0.00e+00	805.00
IUUC-Cpo-022232	Cavia porcellus	75.96	0.00e+00	785.00
IUUC-Csa-023593	Chlorocebus sabaeus	76.30	0.00e+00	838.00
IUUC-Csv-026177	Ciona savignyi	28.57	8.00e-03	33.10
IUUC-Dno-029900	Dasypus novemcinctus	73.29	0.00e+00	796.00
IUUC-Ete-032473	Echinops telfairi	69.73	0.00e+00	724.00
IUUC-Eeu-034670	Erinaceus europaeus	73.39	0.00e+00	773.00
IUUC-Fca-035871	Felis catus	76.15	0.00e+00	788.00
IUUC-Gga-041105	Gallus gallus	91.40	0.00e+00	929.00
IUUC-Ggo-045472	Gorilla gorilla	74.74	0.00e+00	811.00
IUUC-Hsa-046473	Homo sapiens	74.05	0.00e+00	812.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	75.17	0.00e+00	803.00
IUUC-Mcc-055261	Macaca mulatta	76.12	0.00e+00	839.00
IUUC-Meu-056477	Macropus eugenii	72.64	0.00e+00	712.00
IUUC-Mga-059533	Meleagris gallopavo	88.24	0.00e+00	885.00
IUUC-Mdo-062847	Monodelphis domestica	79.79	0.00e+00	830.00
IUUC-Mmu-064260	Mus musculus	71.92	0.00e+00	728.00
IUUC-Mlu-068039	Myotis lucifugus	73.29	0.00e+00	798.00
IUUC-Nle-069260	Nomascus leucogenys	73.70	0.00e+00	809.00
IUUC-Ocu-073824	Oryctolagus cuniculus	85.07	0.00e+00	734.00
IUUC-Osa-085322	Oryza sativa	28.57	4.20e-01	28.90
IUUC-Oga-088124	Otolemur garnettii	74.11	0.00e+00	809.00
IUUC-Oar-090086	Ovis aries	74.32	0.00e+00	799.00
IUUC-Ptr-091622	Pan troglodytes	75.86	0.00e+00	789.00
IUUC-Pan-092724	Papio anubis	76.64	0.00e+00	837.00
IUUC-Psi-093333	Pelodiscus sinensis	84.89	0.00e+00	841.00
IUUC-Pab-098667	Pongo abelii	73.70	0.00e+00	805.00
IUUC-Pva-102136	Pteropus vampyrus	73.50	0.00e+00	793.00
IUUC-Sha-106732	Sarcophilus harrisii	79.30	0.00e+00	768.00
IUUC-Sar-113562	Sorex araneus	68.39	0.00e+00	639.00
IUUC-Ssc-116191	Sus scrofa	74.49	0.00e+00	795.00
IUUC-Tsy-119343	Tarsius syrichta	71.33	0.00e+00	760.00
IUUC-Tur-126860	Triticum urartu	21.95	2.90e-01	29.60
IUUC-Tbe-127283	Tupaia belangeri	81.90	0.00e+00	695.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence