iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054459

Ensembl Protein ID

ENSLAFP00000009245.3

UniProt Accession

G3T6R9; G3T6R9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KLHL15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000011049.3	ENSLAFT00000011049.3	ENSLAFP00000009245.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.40e-19	69.8	32	96

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lv+++ +f+ahk+ La++S++F+ +f+ +++e++ ++++++k++ ++ f+++l+F+Y g++++
   Q: 32   DVTLVIEDHQFQAHKALLATQSDYFRIMFTADMRERD-QDKIHLKGLTATGFSHVLQFMYYGTIEL 96
           9***********************************9.************************9876 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAGDVEGFCS SIHDTSVSAG FRALYEEGLL LDVTLVIEDH QFQAHKALLA TQSDYFRIMF 60
TADMRERDQD KIHLKGLTAT GFSHVLQFMY YGTIELSMST VHEILQAAMY VQLIEVVKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGGGG ACGTGGAAGG ATTTTGTTCC TCCATCCATG ACACCAGTGT CTCTGCTGGG 60
TTCAGAGCAC TGTATGAAGA GGGCTTGCTT CTTGATGTCA CTCTGGTCAT TGAAGATCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030597--KLHL15
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005634--C:nucleus
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome

KEGG

lav:100654716

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001418	Ailuropoda melanoleuca	99.01	0.00e+00	1162.00
IUUC-Apl-003970	Anas platyrhynchos	95.20	0.00e+00	1123.00
IUUC-Aca-005217	Anolis carolinensis	94.37	0.00e+00	1112.00
IUUC-Ame-011065	Astyanax mexicanus	86.92	0.00e+00	1077.00
IUUC-Bta-012443	Bos taurus	98.18	0.00e+00	1155.00
IUUC-Cja-019831	Callithrix jacchus	98.18	0.00e+00	1155.00
IUUC-Cfa-020941	Canis familiaris	99.01	0.00e+00	1162.00
IUUC-Cpo-021730	Cavia porcellus	98.18	0.00e+00	1157.00
IUUC-Csa-023247	Chlorocebus sabaeus	98.18	0.00e+00	1156.00
IUUC-Dre-028474	Danio rerio	85.93	0.00e+00	1075.00
IUUC-Dno-029411	Dasypus novemcinctus	99.17	0.00e+00	1164.00
IUUC-Dor-030576	Dipodomys ordii	98.01	0.00e+00	1155.00
IUUC-Ete-032327	Echinops telfairi	95.53	0.00e+00	1116.00
IUUC-Eca-033477	Equus caballus	98.84	0.00e+00	1162.00
IUUC-Fca-035546	Felis catus	98.84	0.00e+00	1161.00
IUUC-Fal-037370	Ficedula albicollis	95.20	0.00e+00	1123.00
IUUC-Gmo-038961	Gadus morhua	83.42	0.00e+00	990.00
IUUC-Gga-041049	Gallus gallus	95.03	0.00e+00	1122.00
IUUC-Gac-042003	Gasterosteus aculeatus	82.76	0.00e+00	995.00
IUUC-Ggo-044451	Gorilla gorilla	98.18	0.00e+00	1156.00
IUUC-Hsa-045874	Homo sapiens	98.01	0.00e+00	1154.00
IUUC-Itr-048357	Ictidomys tridecemlineatus	98.34	0.00e+00	1158.00
IUUC-Lch-049603	Latimeria chalumnae	90.68	4.00e-128	450.00
IUUC-Loc-052300	Lepisosteus oculatus	89.74	0.00e+00	1103.00
IUUC-Mcc-054846	Macaca mulatta	98.18	0.00e+00	1156.00
IUUC-Meu-056797	Macropus eugenii	98.21	6.00e-115	407.00
IUUC-Mga-059446	Meleagris gallopavo	95.20	0.00e+00	1123.00
IUUC-Mmr-061125	Microcebus murinus	97.35	0.00e+00	1149.00
IUUC-Mdo-062947	Monodelphis domestica	93.38	0.00e+00	1086.00
IUUC-Mmu-063708	Mus musculus	98.68	0.00e+00	1160.00
IUUC-Mpu-066447	Mustela putorius furo	98.83	0.00e+00	1152.00
IUUC-Mlu-066999	Myotis lucifugus	93.41	0.00e+00	968.00
IUUC-Nle-069918	Nomascus leucogenys	98.18	0.00e+00	1156.00
IUUC-Ont-071446	Oreochromis niloticus	84.49	0.00e+00	987.00
IUUC-Oan-072872	Ornithorhynchus anatinus	91.56	0.00e+00	1117.00
IUUC-Ocu-073969	Oryctolagus cuniculus	97.75	0.00e+00	904.00
IUUC-Ola-087557	Oryzias latipes	84.15	3.00e-153	534.00
IUUC-Oga-088567	Otolemur garnettii	98.01	0.00e+00	1151.00
IUUC-Oar-089882	Ovis aries	98.34	0.00e+00	1156.00
IUUC-Ptr-091229	Pan troglodytes	98.13	0.00e+00	1124.00
IUUC-Pan-091977	Papio anubis	98.18	0.00e+00	1156.00
IUUC-Psi-093496	Pelodiscus sinensis	95.24	7.00e-156	543.00
IUUC-Pfo-096759	Poecilia formosa	82.90	0.00e+00	999.00
IUUC-Pab-098480	Pongo abelii	98.18	0.00e+00	1156.00
IUUC-Rno-105500	Rattus norvegicus	98.68	0.00e+00	1160.00
IUUC-Sha-106521	Sarcophilus harrisii	93.39	0.00e+00	1058.00
IUUC-Ssc-116372	Sus scrofa	98.84	0.00e+00	1162.00
IUUC-Tgu-116481	Taeniopygia guttata	95.20	0.00e+00	1123.00
IUUC-Tru-118542	Takifugu rubripes	81.45	0.00e+00	990.00
IUUC-Tsy-118848	Tarsius syrichta	97.73	5.00e-127	447.00
IUUC-Tni-119989	Tetraodon nigroviridis	82.57	0.00e+00	936.00
IUUC-Tbe-127485	Tupaia belangeri	98.51	0.00e+00	1158.00
IUUC-Ttr-129214	Tursiops truncatus	98.51	0.00e+00	1155.00
IUUC-Vpa-130261	Vicugna pacos	95.86	0.00e+00	1117.00
IUUC-Xtr-132092	Xenopus tropicalis	89.85	0.00e+00	1025.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence