iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020702

Ensembl Protein ID

ENSCAFP00000014968.2

UniProt Accession

E2RJS3; E2RJS3_CANLF

Genbank Protein ID

ENSCAFP00000014968

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03017577

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000010192.3	ENSCAFT00000016184.2	ENSCAFP00000014968.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	2.30e-51	175.2	30	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC+++fC++Clkqyl+l+i+eg+ + i cp++ c ++  l+e+ei++ lv  ++++ y++l++e++v+ d+ +
   Q: 30   CKLCLCEQSLDKMTTLQECRCIFCTACLKQYLQLAIREGCGAPIACPDTVCLNHgtLQEAEIAC-LVPMDQFQLYQRLKFEREVHLDPYR 118
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +++++  + ++vec++c+ +fC++Ck++wH+++sC++ +  +  te   + a   + +ea +k+Cp C+vyie+neg
   Q: 119  TWCPVADCQTVCPVASSDpgQPVQVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTE---HGALFGTDAEAPIKQCPVCRVYIERNEG 205
           *************9998877889999*****************************9999...89************************** PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 206  CAQMMCKNCKHTFCWYC 222
           ***************** PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MGSIGRLHYL TMTTENPMPG DLAPAPLVTC KLCLCEQSLD KMTTLQECRC IFCTACLKQY 60
LQLAIREGCG APIACPDTVC LNHGTLQEAE IACLVPMDQF QLYQRLKFER EVHLDPYRTW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNCCTCCCCC CCTCCCCGCC CGCCCGGCCG CAGCCCTGCG GAGCGCAGAG CGCCGAGCGC 60
CGAGCCCGGG GCGCGGAGCC GGCCGGGCCT CCCCGGGGCG CGCAGCCTGG AGGCGGGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

cfa:488237

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	96.04	2.00e-173	601.00
IUUC-Atr-002709	Amborella trichopoda	28.14	6.00e-18	86.30
IUUC-Apl-004112	Anas platyrhynchos	80.07	2.00e-127	448.00
IUUC-Aca-004533	Anolis carolinensis	75.91	4.00e-136	477.00
IUUC-Bta-012641	Bos taurus	92.76	6.00e-167	579.00
IUUC-Cja-019626	Callithrix jacchus	79.21	5.00e-140	490.00
IUUC-Cpo-022147	Cavia porcellus	93.07	2.00e-167	581.00
IUUC-Csa-023473	Chlorocebus sabaeus	94.72	2.00e-172	597.00
IUUC-Cho-024298	Choloepus hoffmanni	90.27	2.00e-140	491.00
IUUC-Dre-028099	Danio rerio	64.66	2.00e-91	328.00
IUUC-Dno-029122	Dasypus novemcinctus	86.51	1.00e-154	539.00
IUUC-Dor-030669	Dipodomys ordii	93.99	5.00e-131	459.00
IUUC-Ete-033141	Echinops telfairi	78.55	7.00e-129	452.00
IUUC-Eca-034360	Equus caballus	94.72	3.00e-171	593.00
IUUC-Eeu-034538	Erinaceus europaeus	72.77	7.00e-85	306.00
IUUC-Fca-036055	Felis catus	93.40	7.00e-169	585.00
IUUC-Fal-037339	Ficedula albicollis	78.85	3.00e-130	457.00
IUUC-Gmo-038780	Gadus morhua	61.17	1.00e-85	309.00
IUUC-Gga-040256	Gallus gallus	78.29	1.00e-130	459.00
IUUC-Gac-042127	Gasterosteus aculeatus	63.21	4.00e-92	330.00
IUUC-Ggo-044867	Gorilla gorilla	95.71	3.00e-173	600.00
IUUC-Hsa-046928	Homo sapiens	95.38	8.00e-173	598.00
IUUC-Hvu-047484	Hordeum vulgare	30.14	5.00e-17	82.00
IUUC-Itr-048250	Ictidomys tridecemlineatus	97.41	3.00e-110	390.00
IUUC-Lch-050168	Latimeria chalumnae	72.46	8.00e-130	456.00
IUUC-Lpe-051649	Leersia perrieri	27.72	3.00e-16	80.90
IUUC-Loc-052150	Lepisosteus oculatus	60.22	2.00e-86	312.00
IUUC-Laf-053967	Loxodonta africana	93.07	2.00e-168	584.00
IUUC-Mcc-055898	Macaca mulatta	94.72	2.00e-172	597.00
IUUC-Meu-056628	Macropus eugenii	97.44	2.00e-43	168.00
IUUC-Mtr-057989	Medicago truncatula	26.42	5.00e-19	87.80
IUUC-Mga-059820	Meleagris gallopavo	77.22	8.00e-129	452.00
IUUC-Mmr-060680	Microcebus murinus	92.74	7.00e-167	579.00
IUUC-Mdo-062839	Monodelphis domestica	84.54	8.00e-153	532.00
IUUC-Mmu-063339	Mus musculus	86.14	3.00e-146	510.00
IUUC-Mac-065414	Musa acuminata	29.38	3.00e-19	89.40
IUUC-Mpu-065973	Mustela putorius furo	95.05	4.00e-172	597.00
IUUC-Mlu-067112	Myotis lucifugus	93.07	8.00e-161	559.00
IUUC-Nle-069795	Nomascus leucogenys	95.05	4.00e-173	600.00
IUUC-Opr-070390	Ochotona princeps	87.79	2.00e-153	535.00
IUUC-Ont-072329	Oreochromis niloticus	64.34	1.00e-88	319.00
IUUC-Oan-072980	Ornithorhynchus anatinus	78.25	7.00e-137	479.00
IUUC-Ocu-073845	Oryctolagus cuniculus	93.40	1.00e-168	585.00
IUUC-Ola-086872	Oryzias latipes	61.05	1.00e-83	302.00
IUUC-Oga-088954	Otolemur garnettii	93.07	5.00e-168	583.00
IUUC-Oar-089879	Ovis aries	93.42	6.00e-168	582.00
IUUC-Ptr-090685	Pan troglodytes	95.38	8.00e-173	598.00
IUUC-Pan-092086	Papio anubis	94.39	3.00e-172	597.00
IUUC-Psi-093481	Pelodiscus sinensis	79.87	7.00e-137	479.00
IUUC-Pfo-096065	Poecilia formosa	65.15	2.00e-91	328.00
IUUC-Pab-098031	Pongo abelii	94.72	1.00e-171	595.00
IUUC-Pca-100936	Procavia capensis	90.43	2.00e-163	567.00
IUUC-Pva-102864	Pteropus vampyrus	84.16	4.00e-148	516.00
IUUC-Rno-105503	Rattus norvegicus	86.14	3.00e-146	510.00
IUUC-Sha-107425	Sarcophilus harrisii	84.87	2.00e-152	531.00
IUUC-Stu-112736	Solanum tuberosum	27.36	2.00e-18	85.90
IUUC-Ssc-115458	Sus scrofa	91.86	5.00e-157	546.00
IUUC-Tgu-117226	Taeniopygia guttata	77.78	6.00e-130	456.00
IUUC-Tru-118362	Takifugu rubripes	64.66	4.00e-93	334.00
IUUC-Tsy-119255	Tarsius syrichta	95.38	1.00e-172	598.00
IUUC-Tni-120140	Tetraodon nigroviridis	61.73	6.00e-88	317.00
IUUC-Tae-124420	Triticum aestivum	30.96	6.00e-18	85.50
IUUC-Tbe-127306	Tupaia belangeri	93.07	4.00e-168	583.00
IUUC-Ttr-128923	Tursiops truncatus	93.09	4.00e-156	543.00
IUUC-Vpa-130148	Vicugna pacos	93.40	4.00e-168	583.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence