iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037186

Ensembl Protein ID

ENSFALP00000009258.1

UniProt Accession

U3K2K4; U3K2K4_FICAL

Genbank Protein ID

ENSFALP00000009258

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01011004

Gene Name

BAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000008877.1	ENSFALT00000009297.1	ENSFALP00000009258.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.60e-126	422.1	1	638

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 88   iffakqvigNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytke 176
           +ffa+q+i+NsCat+Allsvllnc+++  dlG+tlsr+k++tk++spe+k++a+gn+++l+++hns+ar+e+r++pe+q++ ++++t+e
   Q: 1    MFFAHQLIPNSCATHALLSVLLNCNNV--DLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTME 87
           8************************99..************************************************************ PP
   S: 177  afhfvsyvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkid.. 259
           afhfvsyv+i+grl+eldglk++P+d+g++ ++ee++dk+++v+  +eri+l++++e    irfnl+a+v+drr++++ +l++lk++  
   Q: 88   AFHFVSYVPIKGRLFELDGLKVYPIDHGPWADDEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRMKYESKLHILKMNrq 174
           ********************************************..******************************************* PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 175  tvlealqqlirvtqpeliqtqksqesqpaeeakpassktvtpesthadgtdeptsqghptatqsppskskpvpkatasgingappanpn 263
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 264  pivqrlpafldnhnyakspmqeeedlaagvgrnrvpvrqhqqysddeddyddddeeevrntnsairykrkgqvkqehvagaadgqlsvl 352
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 353  qpntinvlaeklkesqkdlsiplsiktsgggaavavvthsqpsptpsnestdtaseigsafnsplrspirsanptrpsspvtshiskvl 441
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 442  fgeedgllrvdcmrynravrdlgpivssgllhltedgvfcplaavdgknspssikpseevpvaikleekegseasdskekvglgrtsdh 530
           ***************************************************************************************** PP
   S: 260  ........keLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveetisevrefgvnegrla 340
                   keLl+Llk++e+e++++ea+l++e+ekrkkfkidd+rRt+nydefic+fi++la+eg+l+ lve++is++r++gv++grl+
   Q: 531  pggekyspKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLASLVEQNISVRRRQGVSIGRLH 619
           ***************************************************************************************** PP
   S: 341  kqrkqgrekkirplkrkrk 359
           kqrk++r+k++rp+k+kr+
   Q: 620  KQRKPDRRKRSRPYKAKRQ 638
           *****************97 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MFFAHQLIPN SCATHALLSV LLNCNNVDLG PTLSRMKDFT KGFSPESKGY AIGNAPELAK 60
AHNSHARPEP RHLPEKQNGI SAVRTMEAFH FVSYVPIKGR LFELDGLKVY PIDHGPWADD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGAAAATTG AGCTGACTGC CTTTGCTTTG GCATCATAGT GGCAGCTGCT GCTCAGTTGC 60
TGATGTCTGA TAGTCCTTGT TTTCTTGCTG TTTTATCTGT ATTTCTGGTT ATGTCCTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001578--Peptidase_C12_UCH

Pfam

PF01088--Peptidase_C12

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0035517--C:PR-DUB complex
GO:0003682--F:chromatin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0061519--P:macrophage homeostasis
GO:0035522--P:monoubiquitinated histone H2A deubiquitination
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0071108--P:protein K48-linked deubiquitination
GO:0051726--P:regulation of cell cycle
GO:0001558--P:regulation of cell growth
GO:1900015--P:regulation of cytokine production involved in inflammatory response
GO:0010035--P:response to inorganic substance
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001263	Ailuropoda melanoleuca	80.09	0.00e+00	977.00
IUUC-Apl-003405	Anas platyrhynchos	79.28	0.00e+00	744.00
IUUC-Aca-004836	Anolis carolinensis	82.14	0.00e+00	1060.00
IUUC-Ame-011946	Astyanax mexicanus	60.03	0.00e+00	742.00
IUUC-Bta-013131	Bos taurus	77.14	0.00e+00	829.00
IUUC-Cja-019599	Callithrix jacchus	82.18	0.00e+00	1023.00
IUUC-Cfa-021003	Canis familiaris	80.95	0.00e+00	971.00
IUUC-Cpo-022143	Cavia porcellus	81.57	0.00e+00	1009.00
IUUC-Csa-023477	Chlorocebus sabaeus	81.57	0.00e+00	1008.00
IUUC-Cho-024734	Choloepus hoffmanni	67.84	0.00e+00	632.00
IUUC-Csv-025842	Ciona savignyi	58.95	4.00e-62	231.00
IUUC-Dre-027793	Danio rerio	63.77	0.00e+00	765.00
IUUC-Dno-029253	Dasypus novemcinctus	81.72	0.00e+00	1026.00
IUUC-Dor-030891	Dipodomys ordii	80.62	0.00e+00	980.00
IUUC-Dme-031796	Drosophila melanogaster	63.49	2.00e-64	239.00
IUUC-Ete-032646	Echinops telfairi	76.28	3.00e-152	532.00
IUUC-Eca-033805	Equus caballus	81.08	0.00e+00	991.00
IUUC-Eeu-035216	Erinaceus europaeus	81.63	2.00e-130	459.00
IUUC-Fca-035611	Felis catus	79.88	0.00e+00	946.00
IUUC-Gmo-038824	Gadus morhua	65.14	7.00e-135	474.00
IUUC-Gga-040875	Gallus gallus	92.18	0.00e+00	1092.00
IUUC-Gac-042226	Gasterosteus aculeatus	67.60	0.00e+00	805.00
IUUC-Ggo-045122	Gorilla gorilla	80.80	0.00e+00	1018.00
IUUC-Hsa-045882	Homo sapiens	80.65	0.00e+00	1013.00
IUUC-Itr-048185	Ictidomys tridecemlineatus	81.72	0.00e+00	1009.00
IUUC-Lch-049960	Latimeria chalumnae	74.73	0.00e+00	910.00
IUUC-Loc-052408	Lepisosteus oculatus	73.70	7.00e-148	516.00
IUUC-Laf-054187	Loxodonta africana	80.95	0.00e+00	983.00
IUUC-Mcc-055273	Macaca mulatta	81.72	0.00e+00	1021.00
IUUC-Meu-056267	Macropus eugenii	78.46	0.00e+00	976.00
IUUC-Mga-059958	Meleagris gallopavo	96.20	4.00e-129	453.00
IUUC-Mmr-061280	Microcebus murinus	81.44	0.00e+00	999.00
IUUC-Mdo-062625	Monodelphis domestica	82.80	0.00e+00	1045.00
IUUC-Mmu-063853	Mus musculus	79.88	0.00e+00	1006.00
IUUC-Mlu-067771	Myotis lucifugus	79.72	0.00e+00	978.00
IUUC-Opr-070741	Ochotona princeps	81.11	0.00e+00	1013.00
IUUC-Ont-072172	Oreochromis niloticus	66.57	0.00e+00	811.00
IUUC-Oan-073167	Ornithorhynchus anatinus	76.73	0.00e+00	963.00
IUUC-Ocu-074176	Oryctolagus cuniculus	80.74	0.00e+00	981.00
IUUC-Ola-087203	Oryzias latipes	90.11	1.00e-100	359.00
IUUC-Oga-089153	Otolemur garnettii	80.76	0.00e+00	1009.00
IUUC-Oar-090008	Ovis aries	79.57	0.00e+00	977.00
IUUC-Ptr-091234	Pan troglodytes	80.95	0.00e+00	1018.00
IUUC-Pan-092005	Papio anubis	81.72	0.00e+00	1019.00
IUUC-Psi-093995	Pelodiscus sinensis	86.51	3.00e-156	545.00
IUUC-Pma-094110	Petromyzon marinus	47.25	2.00e-122	432.00
IUUC-Pfo-097418	Poecilia formosa	65.92	0.00e+00	793.00
IUUC-Pab-098267	Pongo abelii	80.80	0.00e+00	992.00
IUUC-Pca-101084	Procavia capensis	78.75	0.00e+00	909.00
IUUC-Pva-102292	Pteropus vampyrus	81.92	0.00e+00	667.00
IUUC-Rno-105251	Rattus norvegicus	80.34	0.00e+00	994.00
IUUC-Sha-107100	Sarcophilus harrisii	83.10	0.00e+00	1061.00
IUUC-Sar-113559	Sorex araneus	75.85	0.00e+00	929.00
IUUC-Ssc-115688	Sus scrofa	79.88	0.00e+00	1001.00
IUUC-Tgu-117424	Taeniopygia guttata	95.21	0.00e+00	1170.00
IUUC-Tru-118585	Takifugu rubripes	65.60	0.00e+00	796.00
IUUC-Tsy-119299	Tarsius syrichta	74.49	0.00e+00	726.00
IUUC-Tni-120808	Tetraodon nigroviridis	64.05	0.00e+00	786.00
IUUC-Tbe-127705	Tupaia belangeri	78.91	4.00e-123	434.00
IUUC-Ttr-128225	Tursiops truncatus	80.49	0.00e+00	969.00
IUUC-Vpa-130193	Vicugna pacos	79.78	6.00e-114	404.00
IUUC-Xtr-132449	Xenopus tropicalis	69.54	0.00e+00	818.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence