iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089305

Ensembl Protein ID

ENSOARP00000009519.1

UniProt Accession

W5PGF3; W5PGF3_SHEEP

Genbank Protein ID

ENSOARP00000009519

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01035040

Gene Name

FBXO4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000008868.1	ENSOART00000009656.1	ENSOARP00000009519.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	94.14	9.00e-178	620.00	IUUC-Hsa-046558

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

FQIDVQLYIL SFLSPHDLCQ LGSTSHYWNE TVRDPILWRY FLLRDLPSWS SVDWKSLPDL 60
EILKKPISEV TNGAFFDYMA VYKMCCPHTR RSSKSSRPMY GAVTSFLHSL IIQNEPRFAM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCAGATTG ATGTACAGCT ATATATTTTG TCATTTCTTT CACCTCATGA TCTGTGTCAG 60
TTGGGAAGTA CAAGTCATTA TTGGAATGAA ACTGTCCGAG ATCCAATTCT GTGGAGATAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0007568--P:aging
GO:0019725--P:cellular homeostasis
GO:0071479--P:cellular response to ionizing radiation
GO:0035726--P:common myeloid progenitor cell proliferation
GO:0048147--P:negative regulation of fibroblast proliferation
GO:1900181--P:negative regulation of protein localization to nucleus
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:2000001--P:regulation of DNA damage checkpoint
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001232	Ailuropoda melanoleuca	96.91	0.00e+00	639.00
IUUC-Apl-004129	Anas platyrhynchos	62.76	3.00e-109	387.00
IUUC-Aca-005076	Anolis carolinensis	54.63	1.00e-107	382.00
IUUC-Aly-006351	Arabidopsis lyrata	34.78	1.00e-03	37.40
IUUC-Ath-007114	Arabidopsis thaliana	37.50	8.00e-03	34.30
IUUC-Ame-011122	Astyanax mexicanus	47.02	4.00e-85	308.00
IUUC-Bta-012449	Bos taurus	98.77	0.00e+00	648.00
IUUC-Bol-015278	Brassica oleracea	23.95	1.00e-05	43.90
IUUC-Cja-019890	Callithrix jacchus	92.59	5.00e-177	613.00
IUUC-Cfa-021134	Canis familiaris	96.60	0.00e+00	635.00
IUUC-Cpo-021693	Cavia porcellus	90.12	4.00e-170	590.00
IUUC-Csa-023540	Chlorocebus sabaeus	93.83	5.00e-176	610.00
IUUC-Dre-028667	Danio rerio	48.29	6.00e-86	310.00
IUUC-Dno-028997	Dasypus novemcinctus	93.83	6.00e-180	623.00
IUUC-Dor-030135	Dipodomys ordii	81.79	9.00e-145	506.00
IUUC-Ete-033149	Echinops telfairi	89.31	2.00e-169	588.00
IUUC-Eca-033292	Equus caballus	95.68	0.00e+00	630.00
IUUC-Eeu-034504	Erinaceus europaeus	73.77	1.00e-130	458.00
IUUC-Fca-036476	Felis catus	96.91	0.00e+00	661.00
IUUC-Fal-036711	Ficedula albicollis	65.75	2.00e-122	431.00
IUUC-Gmo-039592	Gadus morhua	49.68	7.00e-87	313.00
IUUC-Gga-040924	Gallus gallus	64.22	2.00e-126	445.00
IUUC-Gac-041791	Gasterosteus aculeatus	51.25	6.00e-86	310.00
IUUC-Ggo-044736	Gorilla gorilla	94.14	1.00e-175	608.00
IUUC-Hsa-046558	Homo sapiens	94.14	9.00e-176	609.00
IUUC-Itr-048956	Ictidomys tridecemlineatus	93.83	6.00e-175	606.00
IUUC-Lch-049817	Latimeria chalumnae	65.75	3.00e-129	454.00
IUUC-Loc-052226	Lepisosteus oculatus	54.86	2.00e-101	362.00
IUUC-Laf-054371	Loxodonta africana	94.14	2.00e-179	621.00
IUUC-Mcc-054904	Macaca mulatta	93.83	6.00e-176	609.00
IUUC-Meu-056192	Macropus eugenii	57.72	4.00e-94	337.00
IUUC-Mmr-061692	Microcebus murinus	92.59	2.00e-177	615.00
IUUC-Mdo-062666	Monodelphis domestica	79.01	1.00e-148	519.00
IUUC-Mmu-064223	Mus musculus	89.81	8.00e-180	622.00
IUUC-Mpu-066290	Mustela putorius furo	97.53	2.00e-178	617.00
IUUC-Mlu-067882	Myotis lucifugus	95.68	0.00e+00	630.00
IUUC-Nle-070162	Nomascus leucogenys	94.44	1.00e-176	612.00
IUUC-Opr-070789	Ochotona princeps	86.30	8.00e-76	277.00
IUUC-Ont-071690	Oreochromis niloticus	49.26	1.00e-78	286.00
IUUC-Oan-072928	Ornithorhynchus anatinus	77.82	9.00e-113	399.00
IUUC-Ocu-073857	Oryctolagus cuniculus	92.28	5.00e-173	600.00
IUUC-Opu-083947	Oryza punctata	28.30	4.10e-02	32.70
IUUC-Ola-086607	Oryzias latipes	47.46	5.00e-84	304.00
IUUC-Oga-088929	Otolemur garnettii	93.21	1.00e-177	615.00
IUUC-Ptr-090813	Pan troglodytes	88.89	9.00e-165	572.00
IUUC-Pan-092924	Papio anubis	93.29	6.00e-159	553.00
IUUC-Psi-093237	Pelodiscus sinensis	66.87	4.00e-128	451.00
IUUC-Pfo-096259	Poecilia formosa	46.92	1.00e-86	312.00
IUUC-Pab-098292	Pongo abelii	94.44	4.00e-177	613.00
IUUC-Pva-102221	Pteropus vampyrus	97.22	0.00e+00	638.00
IUUC-Rno-105910	Rattus norvegicus	91.98	0.00e+00	634.00
IUUC-Sha-106998	Sarcophilus harrisii	80.56	2.00e-150	524.00
IUUC-Sar-113033	Sorex araneus	89.54	1.00e-165	575.00
IUUC-Ssc-115507	Sus scrofa	96.60	7.00e-176	609.00
IUUC-Tgu-116502	Taeniopygia guttata	65.44	1.00e-119	422.00
IUUC-Tru-118203	Takifugu rubripes	46.27	2.00e-73	269.00
IUUC-Tni-120249	Tetraodon nigroviridis	47.40	5.00e-75	274.00
IUUC-Tbe-128100	Tupaia belangeri	72.45	2.00e-114	405.00
IUUC-Ttr-128299	Tursiops truncatus	96.60	0.00e+00	634.00
IUUC-Vpa-130394	Vicugna pacos	84.26	8.00e-153	533.00
IUUC-Xtr-131825	Xenopus tropicalis	58.95	2.00e-116	412.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence