iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022369

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02004571

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000025009.1	ENSCPOT00000025424.1	ENSCPOP00000020080.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-17	61.7	166	201

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           H++ vtc+a     d +++s+s D  i +WD+r+ +
   Q: 166  HAGQVTCVAAsphKDSMFLSCSEDSRILLWDTRCPK 201
           99******988765599**************99876 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MRKETPPPLV PPAAREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL 60
FKDPCAAPNE GFCSAGVQTE AGVADLTWVG DRGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGAAGG AAACGCCACC TCCTTTAGTG CCCCCGGCGG CCCGCGAATG GAACCTTCCT 60
CCTAATGCGC CAGCCTGTAT GGAACGACAG CTGGAGGCTG CACGATACCG GTCTGGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	91.25	7.00e-179	619.00
IUUC-Apl-003921	Anas platyrhynchos	63.84	7.00e-65	239.00
IUUC-Aca-004870	Anolis carolinensis	69.53	7.00e-119	419.00
IUUC-Ame-011872	Astyanax mexicanus	46.11	2.00e-36	145.00
IUUC-Bta-013325	Bos taurus	91.52	4.00e-180	623.00
IUUC-Cja-019059	Callithrix jacchus	91.23	1.00e-178	618.00
IUUC-Cfa-021036	Canis familiaris	90.03	4.00e-156	543.00
IUUC-Csa-023585	Chlorocebus sabaeus	91.52	2.00e-179	621.00
IUUC-Cho-024470	Choloepus hoffmanni	82.99	5.00e-114	403.00
IUUC-Dno-029867	Dasypus novemcinctus	90.96	1.00e-175	608.00
IUUC-Dor-030834	Dipodomys ordii	64.72	7.00e-114	403.00
IUUC-Dme-031923	Drosophila melanogaster	22.75	2.00e-11	63.20
IUUC-Ete-032245	Echinops telfairi	85.00	2.00e-139	488.00
IUUC-Eca-033360	Equus caballus	90.64	5.00e-172	596.00
IUUC-Eeu-035353	Erinaceus europaeus	91.57	2.00e-176	610.00
IUUC-Fca-036277	Felis catus	92.11	0.00e+00	626.00
IUUC-Fal-037383	Ficedula albicollis	66.67	2.00e-99	355.00
IUUC-Gmo-038575	Gadus morhua	53.45	1.00e-97	349.00
IUUC-Gga-040658	Gallus gallus	70.93	3.00e-128	451.00
IUUC-Gac-041463	Gasterosteus aculeatus	50.94	5.00e-83	301.00
IUUC-Ggo-045120	Gorilla gorilla	89.77	7.00e-177	612.00
IUUC-Hsa-046247	Homo sapiens	90.06	1.00e-177	615.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	92.40	3.00e-176	610.00
IUUC-Lch-049741	Latimeria chalumnae	64.56	5.00e-112	397.00
IUUC-Loc-052695	Lepisosteus oculatus	58.01	5.00e-104	370.00
IUUC-Laf-054535	Loxodonta africana	90.23	2.00e-177	614.00
IUUC-Mcc-054699	Macaca mulatta	91.52	2.00e-179	621.00
IUUC-Meu-056053	Macropus eugenii	77.78	1.00e-139	489.00
IUUC-Mga-059672	Meleagris gallopavo	65.75	5.00e-70	256.00
IUUC-Mmr-060963	Microcebus murinus	93.57	0.00e+00	635.00
IUUC-Mdo-062694	Monodelphis domestica	73.53	2.00e-131	461.00
IUUC-Mmu-064031	Mus musculus	89.47	4.00e-177	613.00
IUUC-Mpu-066408	Mustela putorius furo	92.40	0.00e+00	629.00
IUUC-Mlu-068184	Myotis lucifugus	89.50	2.00e-174	604.00
IUUC-Nle-069251	Nomascus leucogenys	90.94	4.00e-179	620.00
IUUC-Opr-071156	Ochotona princeps	83.33	1.00e-162	565.00
IUUC-Ont-072683	Oreochromis niloticus	56.23	1.00e-94	339.00
IUUC-Oan-073042	Ornithorhynchus anatinus	73.10	3.00e-125	441.00
IUUC-Ocu-074843	Oryctolagus cuniculus	92.13	7.00e-174	602.00
IUUC-Ola-086929	Oryzias latipes	52.72	4.00e-87	314.00
IUUC-Oga-088237	Otolemur garnettii	91.52	2.00e-180	624.00
IUUC-Oar-089312	Ovis aries	91.14	1.00e-163	568.00
IUUC-Ptr-091625	Pan troglodytes	90.06	2.00e-177	614.00
IUUC-Pan-091902	Papio anubis	86.63	3.00e-167	580.00
IUUC-Psi-094035	Pelodiscus sinensis	71.58	1.00e-124	439.00
IUUC-Pma-094565	Petromyzon marinus	61.88	1.00e-56	211.00
IUUC-Pfo-097070	Poecilia formosa	52.88	5.00e-91	327.00
IUUC-Pab-098007	Pongo abelii	90.64	2.00e-178	617.00
IUUC-Pca-100513	Procavia capensis	74.81	4.00e-105	374.00
IUUC-Pva-102821	Pteropus vampyrus	85.67	2.00e-163	567.00
IUUC-Rno-105836	Rattus norvegicus	89.08	8.00e-179	619.00
IUUC-Sha-106847	Sarcophilus harrisii	71.67	8.00e-90	323.00
IUUC-Sar-113451	Sorex araneus	83.97	1.00e-166	578.00
IUUC-Ssc-115978	Sus scrofa	90.35	2.00e-172	597.00
IUUC-Tgu-116745	Taeniopygia guttata	66.81	1.00e-93	335.00
IUUC-Tru-117945	Takifugu rubripes	52.50	9.00e-80	290.00
IUUC-Tsy-119059	Tarsius syrichta	85.88	5.00e-88	316.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.49	3.00e-92	331.00
IUUC-Tbe-127559	Tupaia belangeri	93.86	0.00e+00	637.00
IUUC-Ttr-128505	Tursiops truncatus	89.47	1.00e-173	602.00
IUUC-Vpa-130350	Vicugna pacos	93.96	6.00e-102	362.00
IUUC-Xtr-132939	Xenopus tropicalis	59.94	4.00e-111	394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence