iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-047977

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01010114

Gene Name

RFWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000010196.2	ENSSTOT00000010208.2	ENSSTOP00000009158.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-09	36.4	496	534

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllk 37
           H   +++laf   + +ll+s+s D+tik+ +l t+++++
   Q: 496  HGKQIRGLAFssRSkGLLLSASLDNTIKLTSLETNTVVQ 534
           8889******99446*************98888877766 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MAQEAMDYDL QVQLDHAAEQ LAPTEVVSSQ GRPPLLQPVP VEGVSSQGGP PLPQPAPAEE 60
VSSQGVLPLL HPAPHISIDL TEEVELSEDN VENINPGASE EHRQGSGANH TLQAASLDSM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCAAG AAGCAATGGA CTATGATCTT CAGGTGCAGT TAGATCATGC TGCAGAACAG 60
CTTGCTCCCA CTGAAGTGGT CAGCAGCCAA GGGAGACCAC CCCTCCTTCA ACCTGTTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50294--WD_REPEATS_REGION
PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0035861--C:site of double-strand break
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:2000001--P:regulation of DNA damage checkpoint
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000929	Aegilops tauschii	27.18	2.00e-16	80.50
IUUC-Aml-001188	Ailuropoda melanoleuca	82.78	0.00e+00	1191.00
IUUC-Atr-003034	Amborella trichopoda	25.44	3.00e-14	72.40
IUUC-Apl-003182	Anas platyrhynchos	70.04	0.00e+00	733.00
IUUC-Aca-004619	Anolis carolinensis	69.72	0.00e+00	753.00
IUUC-Aly-006391	Arabidopsis lyrata	29.17	3.00e-31	129.00
IUUC-Ath-007300	Arabidopsis thaliana	26.54	1.00e-28	121.00
IUUC-Ame-010890	Astyanax mexicanus	59.84	0.00e+00	634.00
IUUC-Bta-013051	Bos taurus	76.82	0.00e+00	1124.00
IUUC-Bdi-014519	Brachypodium distachyon	27.94	2.00e-22	100.00
IUUC-Bol-015271	Brassica oleracea	30.06	1.00e-31	130.00
IUUC-Bra-017931	Brassica rapa	29.43	2.00e-31	130.00
IUUC-Cja-019240	Callithrix jacchus	78.13	0.00e+00	1139.00
IUUC-Cfa-021010	Canis familiaris	80.28	0.00e+00	1178.00
IUUC-Cpo-022308	Cavia porcellus	75.42	0.00e+00	1034.00
IUUC-Csa-023501	Chlorocebus sabaeus	80.28	0.00e+00	1228.00
IUUC-Cho-024900	Choloepus hoffmanni	70.71	0.00e+00	1025.00
IUUC-Cin-025403	Ciona intestinalis	35.63	4.00e-95	342.00
IUUC-Csv-025819	Ciona savignyi	37.21	1.00e-44	172.00
IUUC-Cme-027123	Cyanidioschyzon merolae	24.86	6.00e-19	89.00
IUUC-Dre-028354	Danio rerio	57.14	9.00e-167	580.00
IUUC-Dno-029400	Dasypus novemcinctus	76.91	0.00e+00	1118.00
IUUC-Dor-030320	Dipodomys ordii	74.79	0.00e+00	877.00
IUUC-Dme-031949	Drosophila melanogaster	27.98	1.00e-46	181.00
IUUC-Ete-032691	Echinops telfairi	57.04	2.00e-145	508.00
IUUC-Eca-034320	Equus caballus	82.09	0.00e+00	1251.00
IUUC-Fca-035732	Felis catus	79.73	0.00e+00	1125.00
IUUC-Fal-036648	Ficedula albicollis	69.59	0.00e+00	740.00
IUUC-Gmo-038609	Gadus morhua	57.04	2.00e-138	485.00
IUUC-Gga-040522	Gallus gallus	71.48	5.00e-114	404.00
IUUC-Gac-042318	Gasterosteus aculeatus	53.92	3.00e-130	457.00
IUUC-Gma-043184	Glycine max	28.35	9.00e-26	111.00
IUUC-Ggo-044464	Gorilla gorilla	80.03	0.00e+00	1209.00
IUUC-Hsa-045991	Homo sapiens	79.90	0.00e+00	1204.00
IUUC-Hvu-047705	Hordeum vulgare	24.61	6.00e-28	118.00
IUUC-Lch-050112	Latimeria chalumnae	66.54	0.00e+00	680.00
IUUC-Lpe-051605	Leersia perrieri	25.16	3.00e-19	89.70
IUUC-Loc-052241	Lepisosteus oculatus	62.73	0.00e+00	645.00
IUUC-Laf-054559	Loxodonta africana	80.09	0.00e+00	1014.00
IUUC-Mcc-055093	Macaca mulatta	79.90	0.00e+00	1212.00
IUUC-Meu-056417	Macropus eugenii	66.99	0.00e+00	699.00
IUUC-Mtr-058533	Medicago truncatula	27.19	8.00e-30	124.00
IUUC-Mga-059498	Meleagris gallopavo	68.55	0.00e+00	695.00
IUUC-Mmr-061782	Microcebus murinus	81.48	0.00e+00	1193.00
IUUC-Mdo-062053	Monodelphis domestica	73.48	0.00e+00	775.00
IUUC-Mmu-063352	Mus musculus	70.62	0.00e+00	1056.00
IUUC-Mac-064582	Musa acuminata	26.17	3.00e-21	96.70
IUUC-Mpu-066087	Mustela putorius furo	80.93	0.00e+00	1194.00
IUUC-Mlu-068147	Myotis lucifugus	76.18	0.00e+00	1060.00
IUUC-Nle-069503	Nomascus leucogenys	76.80	0.00e+00	1142.00
IUUC-Opr-070479	Ochotona princeps	69.68	0.00e+00	1030.00
IUUC-Ont-071700	Oreochromis niloticus	56.24	1.00e-165	576.00
IUUC-Oan-073702	Ornithorhynchus anatinus	74.90	0.00e+00	792.00
IUUC-Ocu-074886	Oryctolagus cuniculus	75.26	0.00e+00	1131.00
IUUC-Oba-075729	Oryza barthii	31.02	1.00e-26	114.00
IUUC-Obr-076562	Oryza brachyantha	27.39	7.00e-21	95.10
IUUC-Ogl-077615	Oryza glaberrima	31.02	1.00e-26	114.00
IUUC-Ogu-078921	Oryza glumaepatula	31.02	3.00e-27	116.00
IUUC-Oin-079250	Oryza indica	23.78	7.00e-17	81.60
IUUC-Olo-080758	Oryza longistaminata	29.93	4.00e-25	108.00
IUUC-Ome-081707	Oryza meridionalis	24.10	1.00e-18	87.40
IUUC-Oni-083006	Oryza nivara	31.02	6.00e-27	115.00
IUUC-Opu-083650	Oryza punctata	31.19	2.00e-27	116.00
IUUC-Oru-084924	Oryza rufipogon	30.87	2.00e-27	117.00
IUUC-Osa-085820	Oryza sativa	31.02	5.00e-27	115.00
IUUC-Ola-087229	Oryzias latipes	56.19	1.00e-133	469.00
IUUC-Oga-088243	Otolemur garnettii	76.51	0.00e+00	1106.00
IUUC-Oar-089461	Ovis aries	79.49	0.00e+00	1205.00
IUUC-Ptr-090527	Pan troglodytes	80.28	0.00e+00	1205.00
IUUC-Pan-092431	Papio anubis	79.42	0.00e+00	1135.00
IUUC-Psi-093156	Pelodiscus sinensis	70.10	0.00e+00	785.00
IUUC-Pno-094897	Phaeosphaeria nodorum	23.48	2.00e-08	53.10
IUUC-Ppa-095305	Physcomitrella patens	39.82	5.00e-20	93.20
IUUC-Pfo-097065	Poecilia formosa	57.09	1.00e-162	566.00
IUUC-Pab-098272	Pongo abelii	80.28	0.00e+00	1227.00
IUUC-Pop-099827	Populus trichocarpa	31.27	6.00e-31	128.00
IUUC-Pca-100713	Procavia capensis	67.10	0.00e+00	966.00
IUUC-Ppe-102103	Prunus persica	26.68	1.00e-30	127.00
IUUC-Pva-103133	Pteropus vampyrus	88.11	0.00e+00	784.00
IUUC-Pte-104191	Pyrenophora teres	48.00	2.00e-07	49.30
IUUC-Sha-107628	Sarcophilus harrisii	58.70	0.00e+00	840.00
IUUC-Sit-109781	Setaria italica	30.23	1.00e-27	117.00
IUUC-Sly-111779	Solanum lycopersicum	32.01	2.00e-31	130.00
IUUC-Stu-112817	Solanum tuberosum	50.00	2.00e-19	89.00
IUUC-Sar-113124	Sorex araneus	64.64	0.00e+00	732.00
IUUC-Sbi-114107	Sorghum bicolor	26.15	1.00e-30	127.00
IUUC-Ssc-115850	Sus scrofa	80.49	0.00e+00	1152.00
IUUC-Tgu-117295	Taeniopygia guttata	70.02	0.00e+00	748.00
IUUC-Tru-117539	Takifugu rubripes	54.53	1.00e-162	565.00
IUUC-Tsy-118805	Tarsius syrichta	69.15	2.00e-112	399.00
IUUC-Tni-120274	Tetraodon nigroviridis	55.96	5.00e-163	566.00
IUUC-Tca-121162	Theobroma cacao	29.91	4.00e-30	126.00
IUUC-Tae-124822	Triticum aestivum	24.81	1.00e-28	120.00
IUUC-Tur-126162	Triticum urartu	24.63	4.00e-17	83.20
IUUC-Tbe-127884	Tupaia belangeri	74.01	4.00e-86	311.00
IUUC-Ttr-128665	Tursiops truncatus	73.92	1.00e-160	560.00
IUUC-Vpa-130385	Vicugna pacos	83.89	0.00e+00	1195.00
IUUC-Vvi-131464	Vitis vinifera	27.95	3.00e-25	110.00
IUUC-Xtr-132015	Xenopus tropicalis	68.52	0.00e+00	728.00
IUUC-Xma-133109	Xiphophorus maculatus	57.11	2.00e-162	566.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence