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Tag Content
iUUCD ID IUUC-Sbi-114305
Ensembl Protein ID Sb03g011100.1
UniProt Accession C5XH90; C5XH90_SORBI
Genbank Protein ID EES02765.1
Protein Name Presenilin
Genbank Nucleotide ID CM000762
Gene Name SORBI_003G130500
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
Sb03g011100 Sb03g011100.1 Sb03g011100.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/CUE 33.64 1.00e-30 131.00 IUUC-Cel-018553
UBD/Alpha-Helix/CUE 36.28 3.00e-26 117.00 IUUC-Hsa-046822
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Sorghum bicolor
Functional Description
(View)

Functional Description



     Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
Protein Sequence
(Fasta)
MDPAAASPVP ALAPAVEEPI SAISVLDTLG AEVLAVMSPV SICMALVVLL ISLLSPPSSG 60
SAAASPPPVT AATLVYLESP NDSPGQKFLG ALLDAAVFVV LVAAVTFVLV ALYYYRCTGF 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Sbi-114305|UBD,CUE|Sorghum bicolor
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGATCCCG CCGCCGCCTC GCCGGTGCCG GCTCTGGCGC CTGCCGTGGA GGAGCCCATC 60
AGCGCCATCT CCGTTCTCGA CACCCTCGGC GCGGAGGTGC TGGCGGTTAT GTCCCCGGTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Sbi-114305|UBD,CUE|Sorghum bicolor
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005798--C:Golgi-associated vesicle
GO:0005887--C:integral component of plasma membrane
GO:0005634--C:nucleus
GO:0004190--F:aspartic-type endopeptidase activity
GO:0004175--F:endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

KEGG sbi:SORBI_03g011100
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000686 Aegilops tauschii 74.05 7.00e-128 450.00
IUUC-Aml-001648 Ailuropoda melanoleuca 32.49 7.00e-33 133.00
IUUC-Atr-003039 Amborella trichopoda 50.84 1.00e-105 375.00
IUUC-Apl-003727 Anas platyrhynchos 31.01 3.00e-31 128.00
IUUC-Aca-004582 Anolis carolinensis 32.43 4.00e-33 134.00
IUUC-Aly-005455 Arabidopsis lyrata 57.64 3.00e-58 218.00
IUUC-Ath-006730 Arabidopsis thaliana 49.79 5.00e-101 360.00
IUUC-Ate-010509 Aspergillus terreus 43.75 2.50e+00 26.90
IUUC-Ame-010686 Astyanax mexicanus 34.91 9.00e-28 116.00
IUUC-Bta-013026 Bos taurus 31.08 8.00e-32 130.00
IUUC-Bdi-014196 Brachypodium distachyon 80.26 2.00e-159 554.00
IUUC-Bol-015841 Brassica oleracea 50.64 8.00e-97 346.00
IUUC-Bra-017580 Brassica rapa 57.21 4.00e-44 171.00
IUUC-Cel-018553 Caenorhabditis elegans 34.64 3.00e-40 158.00
IUUC-Cja-019994 Callithrix jacchus 33.11 1.00e-34 140.00
IUUC-Cfa-020074 Canis familiaris 31.39 8.00e-34 137.00
IUUC-Cpo-022237 Cavia porcellus 31.84 3.00e-34 138.00
IUUC-Cre-022747 Chlamydomonas reinhardtii 42.80 2.00e-42 166.00
IUUC-Csa-023537 Chlorocebus sabaeus 33.33 4.00e-35 141.00
IUUC-Cho-024735 Choloepus hoffmanni 41.12 3.00e-19 89.00
IUUC-Cin-025780 Ciona intestinalis 34.64 6.00e-23 100.00
IUUC-Csv-025967 Ciona savignyi 33.52 2.00e-22 99.00
IUUC-Dre-028526 Danio rerio 33.25 2.00e-36 145.00
IUUC-Dno-029758 Dasypus novemcinctus 31.39 5.00e-33 134.00
IUUC-Dor-030609 Dipodomys ordii 35.75 1.00e-20 93.60
IUUC-Dme-031929 Drosophila melanogaster 34.51 1.00e-27 116.00
IUUC-Ete-032487 Echinops telfairi 41.98 6.00e-13 67.80
IUUC-Eca-033391 Equus caballus 26.67 9.00e-21 93.60
IUUC-Eeu-035134 Erinaceus europaeus 32.06 5.00e-29 120.00
IUUC-Fca-036243 Felis catus 31.17 7.00e-33 134.00
IUUC-Fal-036600 Ficedula albicollis 30.86 5.00e-34 137.00
IUUC-Gmo-039665 Gadus morhua 34.12 1.00e-21 96.70
IUUC-Gga-040993 Gallus gallus 32.21 4.00e-35 141.00
IUUC-Gac-042511 Gasterosteus aculeatus 33.88 1.00e-22 99.80
IUUC-Gma-043822 Glycine max 62.61 6.00e-43 167.00
IUUC-Ggo-045338 Gorilla gorilla 32.67 6.00e-29 121.00
IUUC-Hsa-046822 Homo sapiens 33.33 4.00e-35 141.00
IUUC-Hvu-047141 Hordeum vulgare 75.41 1.00e-137 481.00
IUUC-Itr-048420 Ictidomys tridecemlineatus 33.06 2.00e-35 141.00
IUUC-Lch-049946 Latimeria chalumnae 31.96 4.00e-21 95.10
IUUC-Lpe-051132 Leersia perrieri 81.96 7.00e-159 552.00
IUUC-Loc-052469 Lepisosteus oculatus 30.07 9.00e-26 110.00
IUUC-Laf-053979 Loxodonta africana 31.61 4.00e-30 124.00
IUUC-Mcc-055682 Macaca mulatta 33.33 4.00e-35 141.00
IUUC-Meu-056004 Macropus eugenii 31.05 8.00e-20 90.90
IUUC-Mtr-058392 Medicago truncatula 52.59 3.00e-98 350.00
IUUC-Mga-059466 Meleagris gallopavo 31.53 1.00e-34 139.00
IUUC-Mmr-060890 Microcebus murinus 32.27 1.00e-28 119.00
IUUC-Mdo-062122 Monodelphis domestica 31.17 8.00e-32 130.00
IUUC-Mmu-063823 Mus musculus 31.87 2.00e-27 115.00
IUUC-Mac-064858 Musa acuminata 72.93 1.00e-46 179.00
IUUC-Mpu-065927 Mustela putorius furo 31.39 1.00e-33 136.00
IUUC-Mlu-067079 Myotis lucifugus 31.39 1.00e-36 146.00
IUUC-Nle-070180 Nomascus leucogenys 33.33 4.00e-35 141.00
IUUC-Opr-070344 Ochotona princeps 31.47 6.00e-26 110.00
IUUC-Ont-071846 Oreochromis niloticus 32.67 1.00e-32 133.00
IUUC-Oan-072783 Ornithorhynchus anatinus 32.93 3.00e-28 118.00
IUUC-Ocu-074527 Oryctolagus cuniculus 32.29 8.00e-35 140.00
IUUC-Oba-075256 Oryza barthii 81.44 6.00e-135 472.00
IUUC-Obr-076302 Oryza brachyantha 82.61 2.00e-158 551.00
IUUC-Ogl-077097 Oryza glaberrima 79.70 9.00e-152 529.00
IUUC-Ogu-078570 Oryza glumaepatula 81.86 8.00e-146 509.00
IUUC-Oin-079244 Oryza indica 79.27 6.00e-151 526.00
IUUC-Olo-080484 Oryza longistaminata 80.20 6.00e-105 372.00
IUUC-Ome-081814 Oryza meridionalis 81.25 1.00e-155 541.00
IUUC-Oni-082057 Oryza nivara 81.62 1.00e-145 508.00
IUUC-Opu-084176 Oryza punctata 81.08 1.00e-147 514.00
IUUC-Oru-084618 Oryza rufipogon 81.86 4.00e-146 510.00
IUUC-Osa-085602 Oryza sativa 81.75 3.00e-147 513.00
IUUC-Ola-086707 Oryzias latipes 33.70 5.00e-26 110.00
IUUC-Olu-087811 Ostreococcus lucimarinus 43.89 1.00e-38 152.00
IUUC-Oga-088560 Otolemur garnettii 32.39 1.00e-28 119.00
IUUC-Oar-090348 Ovis aries 30.94 4.00e-35 141.00
IUUC-Ptr-091060 Pan troglodytes 33.33 4.00e-35 141.00
IUUC-Pan-091742 Papio anubis 32.67 5.00e-29 121.00
IUUC-Psi-093505 Pelodiscus sinensis 30.86 1.00e-32 133.00
IUUC-Pma-094612 Petromyzon marinus 36.23 3.00e-22 99.00
IUUC-Ppa-095431 Physcomitrella patens 43.70 2.00e-88 318.00
IUUC-Pfo-097396 Poecilia formosa 29.70 2.00e-33 135.00
IUUC-Pab-098591 Pongo abelii 33.33 3.00e-35 141.00
IUUC-Pop-099661 Populus trichocarpa 46.62 1.00e-80 292.00
IUUC-Pca-101029 Procavia capensis 31.63 3.00e-29 121.00
IUUC-Ppe-101495 Prunus persica 56.51 6.00e-111 393.00
IUUC-Pva-102934 Pteropus vampyrus 30.28 9.00e-26 110.00
IUUC-Rno-105861 Rattus norvegicus 33.03 8.00e-22 97.40
IUUC-Sha-107045 Sarcophilus harrisii 30.94 7.00e-33 134.00
IUUC-Smo-109325 Selaginella moellendorffii 48.25 2.00e-38 152.00
IUUC-Sit-110624 Setaria italica 92.83 8.00e-176 608.00
IUUC-Sly-110865 Solanum lycopersicum 87.14 2.00e-32 129.00
IUUC-Stu-112433 Solanum tuberosum 52.89 4.00e-96 343.00
IUUC-Sar-113169 Sorex araneus 41.82 8.00e-20 90.50
IUUC-Ssc-115766 Sus scrofa 31.32 3.00e-33 135.00
IUUC-Tgu-116469 Taeniopygia guttata 31.68 8.00e-33 133.00
IUUC-Tru-117732 Takifugu rubripes 31.87 1.00e-32 133.00
IUUC-Tsy-119624 Tarsius syrichta 31.96 2.00e-20 92.80
IUUC-Tni-119852 Tetraodon nigroviridis 30.94 2.00e-18 86.30
IUUC-Tca-121865 Theobroma cacao 55.00 9.00e-102 362.00
IUUC-Tae-125925 Triticum aestivum 75.36 1.00e-139 488.00
IUUC-Tur-126237 Triticum urartu 75.47 2.00e-121 427.00
IUUC-Tbe-127632 Tupaia belangeri 32.79 1.00e-28 119.00
IUUC-Ttr-128793 Tursiops truncatus 32.33 3.00e-31 128.00
IUUC-Vpa-130625 Vicugna pacos 40.74 6.00e-19 87.80
IUUC-Vvi-131312 Vitis vinifera 54.45 4.00e-100 357.00
IUUC-Xtr-132756 Xenopus tropicalis 31.39 3.00e-35 142.00
IUUC-Xma-133377 Xiphophorus maculatus 32.40 5.00e-19 88.20
Created Date 25-Jun-2017

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