iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000074747.4	ENSDART00000154812.1	ENSDARP00000129493.1
ENSDARG00000074747.4	ENSDART00000115034.3	ENSDARP00000099894.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-29	101.6	366	400
UBD/Beta-Prp	1.70e-52	179.4	184	399

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgv 34
           Htd+v +++f  s+ ++vsGs+Dgt ++W+l++ +
   Q: 366  HTDKVDSIQFchSGERFVSGSRDGTARIWRLHQRH 400
           ***********6669***************98765 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h s ++c++f + +s ++tgs+d+ +k+w+ ++g l ++l gh ae++++  + +  +++ gs D+ti+vw l+t+ +v +l+gh+ s+
   Q: 184  HLSAVYCIAFDRTGSRIFTGSDDALVKIWSSFDGRLHSTLRGHYAEISDLAVNFENTLIAAGSCDKTIRVWCLRTCAPVAVLQGHSGSI 272
           5567899*****************************************999999999******************************** PP
   S: 98   lslsfsp....sgdklvsGshdrtirv..wdletgqclee....tlsghdgvvn.cvvvhpdgnllvsGslDrtvrlWdlktgkl..lr 173
           +sl+fsp    s+ ++vs++ d t+    wd+++++ +      t++++ gv + c +++p g  l++Gs+D ++r++ l +g+   l 
   Q: 273  TSLQFSPfvkgSKRYMVSTGTDATVCFwqWDVNNNEFSDRqhkfTERPRPGVQTvCSSFSPGGMFLATGSTDDVIRIYYLGSGSPekLA 361
           *********9888*************955566665555449***9999999977255667766*****************666551167 PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtg 212
           +l + htd+v s++f ++g+++vsgs+dgt ++w l++ 
   Q: 362  ELDS-HTDKVDSIQFCHSGERFVSGSRDGTARIWRLHQR 399
           8888.******************************9865 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MADTTARNGS ISPLESELYY LISRYLSTGP CRKAAEALVC ELEENQLLPR RLDWEGNEHP 60
RSYEDLVTAN RHIAPDHLLQ ICKQIGPVLD REVPSGVPGV HSLLGAGRHS LLRTSKDCCA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACACCCCTC CCCCTGCTTC CGGCGTTCAA GCGGAAGTAG CAATGAGCTC AGGCCTCATA 60
CTTCCAATGG CGACCGAAAA CTGGCCGAAC ATAAAGCGGG AGCAATCGTG GAGGCGCACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

KEGG

dre:798858

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ath-006801	Arabidopsis thaliana	31.88	2.00e-69	258.00
IUUC-Ame-010718	Astyanax mexicanus	84.34	0.00e+00	1488.00
IUUC-Bta-013217	Bos taurus	68.72	0.00e+00	1137.00
IUUC-Bra-017829	Brassica rapa	31.67	8.00e-72	266.00
IUUC-Cja-019966	Callithrix jacchus	60.14	0.00e+00	1788.00
IUUC-Cfa-021037	Canis familiaris	67.92	0.00e+00	1126.00
IUUC-Cpo-021934	Cavia porcellus	60.69	0.00e+00	1801.00
IUUC-Cho-024690	Choloepus hoffmanni	74.50	2.00e-172	601.00
IUUC-Cin-025553	Ciona intestinalis	39.12	2.00e-112	400.00
IUUC-Dno-028938	Dasypus novemcinctus	66.02	0.00e+00	1080.00
IUUC-Eca-034349	Equus caballus	68.29	0.00e+00	1072.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	62.21	0.00e+00	686.00
IUUC-Lch-049662	Latimeria chalumnae	70.35	0.00e+00	1210.00
IUUC-Lpe-051619	Leersia perrieri	30.21	2.00e-65	245.00
IUUC-Loc-052853	Lepisosteus oculatus	73.36	0.00e+00	1283.00
IUUC-Laf-053848	Loxodonta africana	68.69	0.00e+00	1122.00
IUUC-Mcc-054638	Macaca mulatta	66.92	0.00e+00	1129.00
IUUC-Meu-056739	Macropus eugenii	60.52	0.00e+00	856.00
IUUC-Mga-060165	Meleagris gallopavo	62.27	0.00e+00	1812.00
IUUC-Mdo-062074	Monodelphis domestica	68.33	0.00e+00	1120.00
IUUC-Nle-069402	Nomascus leucogenys	67.64	0.00e+00	1118.00
IUUC-Ont-072298	Oreochromis niloticus	76.12	0.00e+00	2255.00
IUUC-Oba-075709	Oryza barthii	29.47	2.00e-59	225.00
IUUC-Obr-076619	Oryza brachyantha	30.72	1.00e-67	253.00
IUUC-Ogl-077493	Oryza glaberrima	27.08	6.00e-29	124.00
IUUC-Opu-083233	Oryza punctata	29.62	1.00e-62	236.00
IUUC-Oru-085195	Oryza rufipogon	29.47	2.00e-59	225.00
IUUC-Olu-087745	Ostreococcus lucimarinus	26.40	4.00e-55	210.00
IUUC-Pan-092444	Papio anubis	66.58	0.00e+00	1122.00
IUUC-Pab-097573	Pongo abelii	67.73	0.00e+00	1119.00
IUUC-Sha-106680	Sarcophilus harrisii	68.14	0.00e+00	1123.00
IUUC-Vpa-130160	Vicugna pacos	57.82	0.00e+00	1425.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence