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Tag Content
UUCD2 ID IUUC-Cfa-021127
UUCD1 version UUC-CaF-00295
Ensembl Protein ID ENSCAFP00000026359.3
UniProt Accession F1PBA8; F1PBA8_CANLF
Genbank Protein ID ENSCAFP00000026359
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03016300
Gene Name PML
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000025384.3 ENSCAFT00000028343.4 ENSCAFP00000026359.3
ENSCAFG00000025384.3 ENSCAFT00000047900.2 ENSCAFP00000039186.1
ENSCAFG00000025384.3 ENSCAFT00000028342.3 ENSCAFP00000026358.3
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 78.05 0.00e+00 1231.00 IUUC-Hsa-045861
E3 activity/RING/RING 66.71 0.00e+00 984.00 IUUC-Mmu-063118
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Canis familiaris
Protein Sequence
(Fasta)
PREEPPRHLL TSRQPSPAPH PTSLVPQQAL EEEFQFLCCQ SCQAEAKCPK LLPCLHTLCS 60
GCLEASGLRC SICQVPGPLG AGSPALDNVF FESLQRRLSV YRQIVDAQAV CTRCKEPADF 120
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Protein Fasta Sequence



>IUUC-Cfa-021127|E3,RING|Canis familiaris
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Nucleotide Sequence
(Fasta)
CCCAGAGAGG AGCCCCCACG CCACCTCCTC ACGTCCAGAC AGCCCAGCCC AGCCTGGTGA 60
CTCAAGGGCC TCACTGGAGC CAACTCTGCA CCCTCTGCAG CCCGGCCAGG CCTCTCTAAG 120
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Nucleotide Fasta Sequence



>IUUC-Cfa-021127|E3,RING|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR021978--DUF3583
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12126--DUF3583
PF00643--zf-B_box

SMART

SM00336--BBOX

Gene Ontology

GO:0005829--C:cytosol
GO:0042406--C:extrinsic component of endoplasmic reticulum membrane
GO:0000784--C:nuclear chromosome, telomeric region
GO:0016363--C:nuclear matrix
GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0007050--P:cell cycle arrest
GO:0045165--P:cell fate commitment
GO:0071353--P:cellular response to interleukin-4
GO:0090398--P:cellular senescence
GO:0032922--P:circadian regulation of gene expression
GO:0007182--P:common-partner SMAD protein phosphorylation
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0032469--P:endoplasmic reticulum calcium ion homeostasis
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0010761--P:fibroblast migration
GO:0045087--P:innate immune response
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0051457--P:maintenance of protein location in nucleus
GO:0030099--P:myeloid cell differentiation
GO:0016525--P:negative regulation of angiogenesis
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0050713--P:negative regulation of interleukin-1 beta secretion
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1902187--P:negative regulation of viral release from host cell
GO:0030578--P:PML body organization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0045345--P:positive regulation of MHC class I biosynthetic process
GO:0032206--P:positive regulation of telomere maintenance
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006461--P:protein complex assembly
GO:0010522--P:regulation of calcium ion transport into cytosol
GO:0030155--P:regulation of cell adhesion
GO:2000779--P:regulation of double-strand break repair
GO:0001932--P:regulation of protein phosphorylation
GO:0010332--P:response to gamma radiation
GO:0001666--P:response to hypoxia
GO:0009411--P:response to UV
GO:0048384--P:retinoic acid receptor signaling pathway
GO:0007184--P:SMAD protein import into nucleus
GO:0007179--P:transforming growth factor beta receptor signaling pathway

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001901 Ailuropoda melanoleuca 81.20 0.00e+00 1238.00
IUUC-Bta-012427 Bos taurus 72.20 0.00e+00 1127.00
IUUC-Cja-019029 Callithrix jacchus 77.82 0.00e+00 1173.00
IUUC-Cpo-022553 Cavia porcellus 67.97 0.00e+00 952.00
IUUC-Csa-023187 Chlorocebus sabaeus 75.79 0.00e+00 809.00
IUUC-Cho-024937 Choloepus hoffmanni 64.03 1.00e-92 334.00
IUUC-Dno-029326 Dasypus novemcinctus 72.86 0.00e+00 1077.00
IUUC-Dor-030808 Dipodomys ordii 59.67 0.00e+00 665.00
IUUC-Ete-032746 Echinops telfairi 53.37 2.00e-165 576.00
IUUC-Eca-033234 Equus caballus 76.16 0.00e+00 1123.00
IUUC-Fca-035648 Felis catus 82.02 0.00e+00 1281.00
IUUC-Ggo-044927 Gorilla gorilla 78.05 0.00e+00 1226.00
IUUC-Hsa-045861 Homo sapiens 78.05 0.00e+00 1225.00
IUUC-Itr-047861 Ictidomys tridecemlineatus 75.18 0.00e+00 1169.00
IUUC-Loc-052276 Lepisosteus oculatus 34.69 3.00e-50 193.00
IUUC-Laf-054059 Loxodonta africana 72.58 0.00e+00 1078.00
IUUC-Meu-056495 Macropus eugenii 53.50 3.00e-100 359.00
IUUC-Mga-059224 Meleagris gallopavo 45.87 4.00e-43 169.00
IUUC-Mmr-061507 Microcebus murinus 71.79 0.00e+00 1089.00
IUUC-Mdo-062196 Monodelphis domestica 44.89 9.00e-174 604.00
IUUC-Mmu-063118 Mus musculus 66.71 0.00e+00 1015.00
IUUC-Mpu-066024 Mustela putorius furo 74.85 0.00e+00 1145.00
IUUC-Mlu-066980 Myotis lucifugus 74.49 0.00e+00 1105.00
IUUC-Nle-069779 Nomascus leucogenys 77.35 0.00e+00 1164.00
IUUC-Ocu-074016 Oryctolagus cuniculus 66.86 0.00e+00 978.00
IUUC-Oga-089085 Otolemur garnettii 65.55 0.00e+00 958.00
IUUC-Oar-089980 Ovis aries 69.81 0.00e+00 1059.00
IUUC-Ptr-091681 Pan troglodytes 77.99 0.00e+00 1222.00
IUUC-Pan-091965 Papio anubis 75.35 0.00e+00 1155.00
IUUC-Psi-093577 Pelodiscus sinensis 38.05 6.00e-109 388.00
IUUC-Pab-098215 Pongo abelii 73.86 2.00e-179 622.00
IUUC-Pca-100883 Procavia capensis 70.88 0.00e+00 784.00
IUUC-Pva-102465 Pteropus vampyrus 69.85 0.00e+00 749.00
IUUC-Rno-105120 Rattus norvegicus 65.67 0.00e+00 1069.00
IUUC-Sar-113320 Sorex araneus 61.87 2.00e-85 310.00
IUUC-Ssc-116042 Sus scrofa 73.88 0.00e+00 1149.00
IUUC-Tbe-127880 Tupaia belangeri 70.11 2.00e-127 450.00
Created Date 25-Jun-2017

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