iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048231

Ensembl Protein ID

ENSSTOP00000004358.2

UniProt Accession

I3M501; I3M501_ICTTR

Genbank Protein ID

ENSSTOP00000004358

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01088968

Gene Name

MAP3K10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000004863.2	ENSSTOT00000004859.2	ENSSTOP00000004358.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.30e-15	55.1	22	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvieke...eqdegWlkgvkelegkrGlfPenFvekl 62
            + +dyea+ d+eLtl++Gd v+v++++   + degW+ g+   +g+ G+fP+n+v+ +
   Q: 22   TAVFDYEAVGDEELTLRRGDRVQVLSQDcavSGDEGWWTGQ-LPSGRVGVFPSNYVAPA 79
           589**********************77622257*******7.99************875 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MEEEEGAAAK EWGTTPAGPV WTAVFDYEAV GDEELTLRRG DRVQVLSQDC AVSGDEGWWT 60
GQLPSGRVGV FPSNYVAPAA PAPPAGLQLP QEIPFHELQL EEIIGVGGFG KVYRALWHGE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGAGG AGGAGGGGGC GGCGGCCAAG GAGTGGGGCA CGACCCCCGC GGGGCCCGTC 60
TGGACCGCTG TGTTCGACTA CGAGGCGGTG GGCGACGAGG AGCTGACCCT GCGGAGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0003714--F:transcription corepressor activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043507--P:positive regulation of JUN kinase activity
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001187	Ailuropoda melanoleuca	95.18	0.00e+00	951.00
IUUC-Atr-002967	Amborella trichopoda	31.27	3.00e-24	106.00
IUUC-Aca-004768	Anolis carolinensis	76.73	0.00e+00	792.00
IUUC-Aly-006459	Arabidopsis lyrata	33.45	8.00e-30	125.00
IUUC-Ath-006581	Arabidopsis thaliana	33.10	4.00e-29	123.00
IUUC-Ame-011769	Astyanax mexicanus	64.52	0.00e+00	685.00
IUUC-Bta-013545	Bos taurus	97.85	0.00e+00	830.00
IUUC-Bdi-014449	Brachypodium distachyon	32.36	1.00e-25	111.00
IUUC-Bol-016287	Brassica oleracea	32.62	1.00e-28	121.00
IUUC-Bra-016997	Brassica rapa	33.69	8.00e-29	122.00
IUUC-Cja-019696	Callithrix jacchus	96.17	0.00e+00	948.00
IUUC-Cfa-020789	Canis familiaris	77.04	0.00e+00	761.00
IUUC-Cpo-021993	Cavia porcellus	94.74	0.00e+00	962.00
IUUC-Cre-022669	Chlamydomonas reinhardtii	33.64	4.00e-20	92.00
IUUC-Csa-024243	Chlorocebus sabaeus	96.67	0.00e+00	947.00
IUUC-Cho-024961	Choloepus hoffmanni	93.81	1.00e-109	390.00
IUUC-Dre-028573	Danio rerio	72.41	0.00e+00	768.00
IUUC-Dno-029095	Dasypus novemcinctus	94.30	0.00e+00	929.00
IUUC-Dme-032210	Drosophila melanogaster	49.33	2.00e-139	489.00
IUUC-Fca-036250	Felis catus	97.17	0.00e+00	965.00
IUUC-Fal-036753	Ficedula albicollis	66.56	0.00e+00	728.00
IUUC-Gmo-038497	Gadus morhua	71.74	0.00e+00	767.00
IUUC-Gga-040283	Gallus gallus	64.81	0.00e+00	714.00
IUUC-Gac-042509	Gasterosteus aculeatus	71.10	0.00e+00	747.00
IUUC-Gma-043806	Glycine max	30.87	3.00e-27	116.00
IUUC-Ggo-045471	Gorilla gorilla	91.89	0.00e+00	885.00
IUUC-Hsa-046936	Homo sapiens	97.00	0.00e+00	935.00
IUUC-Hvu-047798	Hordeum vulgare	32.27	3.00e-24	106.00
IUUC-Lch-049935	Latimeria chalumnae	74.50	0.00e+00	781.00
IUUC-Loc-052286	Lepisosteus oculatus	67.76	0.00e+00	748.00
IUUC-Laf-053926	Loxodonta africana	66.94	0.00e+00	737.00
IUUC-Mcc-055733	Macaca mulatta	93.75	0.00e+00	941.00
IUUC-Mtr-057869	Medicago truncatula	33.18	2.00e-25	110.00
IUUC-Mmr-061210	Microcebus murinus	64.01	0.00e+00	729.00
IUUC-Mdo-062516	Monodelphis domestica	83.06	0.00e+00	883.00
IUUC-Mmu-064082	Mus musculus	96.30	0.00e+00	981.00
IUUC-Mac-065156	Musa acuminata	31.58	4.00e-27	116.00
IUUC-Mpu-065934	Mustela putorius furo	97.34	0.00e+00	971.00
IUUC-Mlu-068137	Myotis lucifugus	84.41	0.00e+00	904.00
IUUC-Nle-068969	Nomascus leucogenys	64.01	0.00e+00	724.00
IUUC-Opr-070869	Ochotona princeps	77.89	0.00e+00	778.00
IUUC-Ont-072492	Oreochromis niloticus	71.83	0.00e+00	783.00
IUUC-Ocu-074350	Oryctolagus cuniculus	96.09	0.00e+00	942.00
IUUC-Oba-075616	Oryza barthii	34.11	7.00e-25	108.00
IUUC-Obr-076215	Oryza brachyantha	34.91	5.00e-26	112.00
IUUC-Ogl-077159	Oryza glaberrima	34.11	6.00e-25	108.00
IUUC-Ogu-078228	Oryza glumaepatula	34.58	2.00e-25	110.00
IUUC-Oin-079079	Oryza indica	34.21	2.00e-25	110.00
IUUC-Olo-080309	Oryza longistaminata	34.29	2.00e-24	107.00
IUUC-Oni-082428	Oryza nivara	34.11	7.00e-25	108.00
IUUC-Opu-083527	Oryza punctata	34.58	5.00e-25	109.00
IUUC-Oru-084678	Oryza rufipogon	34.21	2.00e-25	110.00
IUUC-Osa-086117	Oryza sativa	34.21	2.00e-25	110.00
IUUC-Ola-087224	Oryzias latipes	71.82	0.00e+00	778.00
IUUC-Oga-088351	Otolemur garnettii	95.35	0.00e+00	999.00
IUUC-Ptr-091607	Pan troglodytes	97.00	0.00e+00	935.00
IUUC-Pan-092403	Papio anubis	96.51	0.00e+00	928.00
IUUC-Pma-094398	Petromyzon marinus	65.63	4.00e-174	605.00
IUUC-Pfo-096104	Poecilia formosa	69.26	0.00e+00	748.00
IUUC-Pab-098396	Pongo abelii	97.00	0.00e+00	935.00
IUUC-Pop-100071	Populus trichocarpa	32.22	6.00e-24	105.00
IUUC-Pca-100945	Procavia capensis	57.48	1.00e-176	613.00
IUUC-Ppe-101208	Prunus persica	32.28	1.00e-26	115.00
IUUC-Pva-102748	Pteropus vampyrus	66.61	0.00e+00	692.00
IUUC-Rno-105688	Rattus norvegicus	96.30	0.00e+00	984.00
IUUC-Smo-109113	Selaginella moellendorffii	33.09	1.00e-26	114.00
IUUC-Sit-110427	Setaria italica	34.58	3.00e-25	110.00
IUUC-Sly-111849	Solanum lycopersicum	35.53	1.00e-26	115.00
IUUC-Stu-112224	Solanum tuberosum	35.53	2.00e-26	114.00
IUUC-Sbi-114009	Sorghum bicolor	31.83	7.00e-24	105.00
IUUC-Ssc-115332	Sus scrofa	95.69	0.00e+00	986.00
IUUC-Tru-117692	Takifugu rubripes	69.48	0.00e+00	772.00
IUUC-Tsy-119412	Tarsius syrichta	91.91	2.00e-65	243.00
IUUC-Tni-120689	Tetraodon nigroviridis	68.71	0.00e+00	760.00
IUUC-Tca-121461	Theobroma cacao	32.65	7.00e-27	115.00
IUUC-Tae-125555	Triticum aestivum	32.10	8.00e-25	108.00
IUUC-Tur-126322	Triticum urartu	32.26	4.00e-25	109.00
IUUC-Tbe-127643	Tupaia belangeri	97.38	0.00e+00	658.00
IUUC-Ttr-128550	Tursiops truncatus	95.36	0.00e+00	999.00
IUUC-Vvi-131372	Vitis vinifera	32.62	6.00e-24	105.00
IUUC-Xtr-132108	Xenopus tropicalis	73.54	0.00e+00	796.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence