iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013385

UUCD1 version

UUC-BoT-00872

Ensembl Protein ID

ENSBTAP00000024312.4

UniProt Accession

Q58D15; Q29RH5; TRI54_BOVIN

Genbank Protein ID

AAX46629.1; AAI14172.1

Protein Name

Tripartite motif-containing protein 54

Genbank Nucleotide ID

BT021782; BC114171

Gene Name

TRIM54

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000018267.4	ENSBTAT00000024312.4	ENSBTAP00000024312.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.70e-09	36.8	26	82

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw...........pglknssskefrCPlCr 46
           C+iCle+f++++++lpC+H  +++C + +                ss ++frCP Cr
   Q: 26   CPICLEMFSKPVVILPCQHNLCRKCANDVfqasnplwqsrSSTTVSSGGRFRCPSCR 82
           *************************87777777888899866777799********8 PP

Organism

Bos taurus

Functional Description
(View)

May bind and stabilize microtubules during myotubes formation.

Protein Sequence
(Fasta)

MNFTVGFKPL LGDAHSMDNL EKQLICPICL EMFSKPVVIL PCQHNLCRKC ANDVFQASNP 60
LWQSRSSTTV SSGGRFRCPS CRHEVVLDRH GVYGLQRNLL VENIIDIYKQ ESSRPLHSKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCGCTGCCC ACAGAGTGGA CAAGAGGGGT TTGGGAAACA GAAGGAGAAG TTTCCAGGGA 60
CAGAGCCATT CAGGGAGAGA GGACGAGAAA AAGCTACGTG TGCCTGGCCA GGGTACAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0479--Metal-binding
KW-0493--Microtubule
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR017903--COS_domain
IPR033492--TRIM54
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51262--COS
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005874--C:microtubule
GO:0005875--C:microtubule associated complex
GO:0030018--C:Z disc
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0055001--P:muscle cell development
GO:0007026--P:negative regulation of microtubule depolymerization

KEGG

bta:535320

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002282	Ailuropoda melanoleuca	96.01	7.00e-133	466.00
IUUC-Cja-019697	Callithrix jacchus	77.72	1.00e-128	452.00
IUUC-Cfa-020995	Canis familiaris	97.58	2.00e-169	587.00
IUUC-Cpo-021913	Cavia porcellus	93.68	0.00e+00	637.00
IUUC-Csa-023342	Chlorocebus sabaeus	96.10	4.00e-177	613.00
IUUC-Cin-025224	Ciona intestinalis	51.46	3.00e-93	335.00
IUUC-Csv-026374	Ciona savignyi	50.53	1.00e-80	292.00
IUUC-Dre-027562	Danio rerio	69.58	1.00e-142	499.00
IUUC-Dno-029582	Dasypus novemcinctus	96.66	1.00e-169	589.00
IUUC-Dor-031139	Dipodomys ordii	93.91	0.00e+00	639.00
IUUC-Ete-032346	Echinops telfairi	98.52	3.00e-109	388.00
IUUC-Eca-033645	Equus caballus	97.30	2.00e-178	618.00
IUUC-Eeu-035333	Erinaceus europaeus	69.41	5.00e-116	410.00
IUUC-Fca-035865	Felis catus	97.58	0.00e+00	631.00
IUUC-Fal-036978	Ficedula albicollis	82.07	1.00e-167	582.00
IUUC-Gga-040452	Gallus gallus	81.52	2.00e-161	561.00
IUUC-Ggo-044467	Gorilla gorilla	85.54	7.00e-171	593.00
IUUC-Hsa-046379	Homo sapiens	95.26	5.00e-176	609.00
IUUC-Itr-047912	Ictidomys tridecemlineatus	93.99	0.00e+00	633.00
IUUC-Lch-050029	Latimeria chalumnae	78.66	4.00e-154	537.00
IUUC-Loc-051801	Lepisosteus oculatus	79.58	3.00e-134	470.00
IUUC-Laf-054215	Loxodonta africana	95.07	0.00e+00	660.00
IUUC-Mcc-055027	Macaca mulatta	86.28	9.00e-172	596.00
IUUC-Meu-056412	Macropus eugenii	92.76	2.00e-166	577.00
IUUC-Mmr-060920	Microcebus murinus	96.10	0.00e+00	630.00
IUUC-Mdo-062832	Monodelphis domestica	95.14	1.00e-163	568.00
IUUC-Mmu-063707	Mus musculus	93.17	5.00e-179	620.00
IUUC-Mlu-067653	Myotis lucifugus	80.43	4.00e-137	480.00
IUUC-Nle-069020	Nomascus leucogenys	95.26	1.00e-176	612.00
IUUC-Opr-070577	Ochotona princeps	78.17	5.00e-143	500.00
IUUC-Ont-072491	Oreochromis niloticus	63.05	1.00e-120	426.00
IUUC-Oan-073101	Ornithorhynchus anatinus	94.55	1.00e-171	595.00
IUUC-Ocu-074454	Oryctolagus cuniculus	97.60	1.00e-176	612.00
IUUC-Oga-088361	Otolemur garnettii	97.90	4.00e-175	607.00
IUUC-Oar-089950	Ovis aries	84.15	3.00e-147	514.00
IUUC-Ptr-090785	Pan troglodytes	85.29	3.00e-170	590.00
IUUC-Pan-092344	Papio anubis	96.38	8.00e-178	615.00
IUUC-Pab-098322	Pongo abelii	91.92	3.00e-166	577.00
IUUC-Pca-100385	Procavia capensis	75.73	5.00e-118	417.00
IUUC-Rno-105134	Rattus norvegicus	93.65	0.00e+00	648.00
IUUC-Sha-106768	Sarcophilus harrisii	94.83	1.00e-176	612.00
IUUC-Tgu-117494	Taeniopygia guttata	80.43	3.00e-158	550.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence