iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107111

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AEFK01217766

Gene Name

UCHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000016418.1	ENSSHAT00000019487.1	ENSSHAP00000019331.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	87.27	5.00e-86	313.00	IUUC-Hsa-045820
DUB/UCH	87.27	5.00e-86	313.00	IUUC-Hsa-045820
UBD/Other/Other	87.27	5.00e-86	313.00	IUUC-Hsa-045820

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

HENFRKKQIE ELKGQEVSSK VYFMKQTVGN SCGTVGLIHA VANNQDKLNF DDGSVLKQFI 60
SETAKLSPED RAKCFEKNEA IQAAHDAVAQ EGQCRVDDEV NFHFILFNNV DGHLYELDGR 120

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Nucleotide Sequence
(Fasta)

CATGAAAACT TCAGGAAAAA ACAGATTGAA GAGCTGAAGG GGCAAGAAGT TAGTTCTAAG 60
GTGTACTTCA TGAAGCAGAC TGTAGGCAAC TCCTGTGGTA CCGTTGGCCT CATCCATGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR030297--UCHL1

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:1904115--C:axon cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0044306--C:neuron projection terminus
GO:0043025--C:neuronal cell body
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0016874--F:ligase activity
GO:0008242--F:omega peptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007628--P:adult walking behavior
GO:0007412--P:axon target recognition
GO:0019896--P:axonal transport of mitochondrion
GO:0008283--P:cell proliferation
GO:0042755--P:eating behavior
GO:0048747--P:muscle fiber development
GO:0043407--P:negative regulation of MAP kinase activity
GO:0050905--P:neuromuscular process
GO:0016579--P:protein deubiquitination
GO:0002931--P:response to ischemia
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001376	Ailuropoda melanoleuca	87.43	4.00e-86	310.00
IUUC-Apl-003693	Anas platyrhynchos	74.10	1.00e-72	265.00
IUUC-Aca-004716	Anolis carolinensis	74.10	4.00e-73	267.00
IUUC-Bta-013521	Bos taurus	87.88	5.00e-87	313.00
IUUC-Cja-019642	Callithrix jacchus	86.06	3.00e-86	310.00
IUUC-Cfa-020442	Canis familiaris	87.88	2.00e-87	315.00
IUUC-Cpo-021723	Cavia porcellus	86.67	2.00e-86	310.00
IUUC-Csa-023626	Chlorocebus sabaeus	86.06	4.00e-86	310.00
IUUC-Cho-024548	Choloepus hoffmanni	92.00	1.00e-23	102.00
IUUC-Dno-029325	Dasypus novemcinctus	87.88	1.00e-87	315.00
IUUC-Dor-030114	Dipodomys ordii	86.06	1.00e-86	311.00
IUUC-Ete-033092	Echinops telfairi	86.06	1.00e-85	308.00
IUUC-Eca-033854	Equus caballus	85.92	3.00e-73	266.00
IUUC-Eeu-034493	Erinaceus europaeus	87.88	2.00e-87	314.00
IUUC-Fal-036693	Ficedula albicollis	72.89	6.00e-71	259.00
IUUC-Gga-041078	Gallus gallus	72.89	1.00e-71	262.00
IUUC-Ggo-044827	Gorilla gorilla	87.27	3.00e-87	314.00
IUUC-Hsa-045820	Homo sapiens	87.27	3.00e-87	314.00
IUUC-Itr-048496	Ictidomys tridecemlineatus	86.67	2.00e-86	311.00
IUUC-Lch-050121	Latimeria chalumnae	70.73	2.00e-68	251.00
IUUC-Laf-053916	Loxodonta africana	84.43	3.00e-84	304.00
IUUC-Mcc-054838	Macaca mulatta	86.06	4.00e-86	310.00
IUUC-Meu-056478	Macropus eugenii	97.58	2.00e-94	337.00
IUUC-Mga-059878	Meleagris gallopavo	72.89	2.00e-71	261.00
IUUC-Mdo-062544	Monodelphis domestica	96.36	1.00e-92	332.00
IUUC-Mmu-063300	Mus musculus	87.27	4.00e-87	313.00
IUUC-Mpu-066128	Mustela putorius furo	86.62	1.00e-73	268.00
IUUC-Mlu-067778	Myotis lucifugus	86.06	3.00e-86	310.00
IUUC-Nle-069686	Nomascus leucogenys	87.27	3.00e-87	314.00
IUUC-Opr-070535	Ochotona princeps	85.45	2.00e-86	311.00
IUUC-Ocu-074590	Oryctolagus cuniculus	87.88	2.00e-87	314.00
IUUC-Oga-089013	Otolemur garnettii	86.06	2.00e-85	308.00
IUUC-Oar-089861	Ovis aries	87.88	5.00e-87	313.00
IUUC-Ptr-091536	Pan troglodytes	87.27	2.00e-87	314.00
IUUC-Pan-092909	Papio anubis	86.06	4.00e-86	310.00
IUUC-Psi-093818	Pelodiscus sinensis	79.52	2.00e-76	277.00
IUUC-Pab-098048	Pongo abelii	87.27	3.00e-87	314.00
IUUC-Pca-100818	Procavia capensis	58.39	6.00e-41	159.00
IUUC-Pva-102954	Pteropus vampyrus	87.88	5.00e-87	313.00
IUUC-Rno-105966	Rattus norvegicus	87.27	4.00e-87	313.00
IUUC-Sar-113190	Sorex araneus	67.54	1.00e-35	140.00
IUUC-Ssc-115908	Sus scrofa	81.93	2.00e-77	281.00
IUUC-Tsy-119561	Tarsius syrichta	85.45	8.00e-85	305.00
IUUC-Tbe-128048	Tupaia belangeri	86.67	9.00e-87	311.00
IUUC-Ttr-128494	Tursiops truncatus	87.20	7.00e-86	309.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence