iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067459

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02038681

Gene Name

NAE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000012976.2	ENSMLUT00000012982.2	ENSMLUP00000011811.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.30e-130	435.6	15	528

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvn 89
           YDRQ+rlwG+++qe+l+sa+v+l++a+++G+E+lKnL+l G+gs+t++D+++v+ ++ +++F+++++++gk++A++++e+l+eln dv+
   Q: 15   YDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLILPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNRAQATMEFLQELNNDVS 103
           ***************************************************************************************** PP
   S: 90   veaheesiteleeeiv.FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd...dppqktiPfc 174
           ++++ees+++l ++++ Ff++f++Vv+++ ++++ ++++++++n ++pl++++t+Gl+G++r+iik++++++s++d   +++++++Pf+
   Q: 104  GSFVEESPENLLDNDPsFFCRFTIVVATQLPESTLLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDnalEDLRLDKPFP 192
           ***************************************************************************************** PP
   S: 175  tlketpn..........aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks......edeenfeeaieiavkafak 247
           +l+e+             ++++++w+v+++k+l+++++e++++ +++++ekee++d++++++ +      edeenfeeai+++++a+++
   Q: 193  ELREHYFqsydlhhmdkRDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEEFRDLIRQGILKnengapEDEENFEEAIKNVNTALNT 281
           *****7777777778879**********************************************9************************ PP
   S: 248  ttins.ikqllksfecdivtkskspfwv............................................................. 274
           t+i+s i +++++++c ++tk++++fw+                                                             
   Q: 282  TQIPSsIGDIFNDDRCINITKQTPSFWIlaralkefvakegqgnlpvrgtipdmiadsgkyiklqnvyrekakkdaaavgnhvakllqs 370
           ***************************************************************************************** PP
   S: 275  ..............sfcsnaealqvp...........ekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds.. 331
                          fcsn++ l+v            ++v+ de+++++++p     lyl+lra++rf+k++gr+pg++++++++d+  
   Q: 371  igrapesisekelkLFCSNSAFLRVVrcrslaeeyglDTVNRDEIISSMDSPdneivLYLMLRAVDRFHKQHGRYPGVSNYQVEEDIgk 459
           ************************777777888888899******999999999*********************************99 PP
   S: 332  avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfdae 404
           + +++t ++    +++g++ +++dd+++e++++++++ +t++a++gG+aaqEviK+++++f+ ++n++++ ++
   Q: 460  LKSCLTGFL----QEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGM 528
           9********....********************************************************9776 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

RAPPGKLSAA QEQKYDRQLR LWGDHGQEAL ESAHVCLINA TATGTEILKN LILPGIGSFT 60
IIDGNQVSGE DAGNNFFLQR SSIGKNRAQA TMEFLQELNN DVSGSFVEES PENLLDNDPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGCCCCTC CGGGAAAACT TTCCCNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0033314--P:mitotic DNA replication checkpoint
GO:0051402--P:neuron apoptotic process
GO:0045116--P:protein neddylation
GO:0043523--P:regulation of neuron apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	43.02	2.00e-127	449.00
IUUC-Aml-002333	Ailuropoda melanoleuca	94.98	0.00e+00	1059.00
IUUC-Atr-002644	Amborella trichopoda	41.71	6.00e-116	410.00
IUUC-Apl-003446	Anas platyrhynchos	83.08	0.00e+00	909.00
IUUC-Aca-004450	Anolis carolinensis	76.12	0.00e+00	902.00
IUUC-Aly-006187	Arabidopsis lyrata	40.19	1.00e-124	439.00
IUUC-Ath-007600	Arabidopsis thaliana	40.57	3.00e-125	442.00
IUUC-Ago-007900	Ashbya gossypii	26.74	1.00e-39	157.00
IUUC-Acl-008333	Aspergillus clavatus	34.47	1.00e-82	300.00
IUUC-Afl-008529	Aspergillus flavus	36.69	7.00e-90	324.00
IUUC-Afu-009071	Aspergillus fumigatus	34.00	6.00e-84	305.00
IUUC-Ani-009443	Aspergillus nidulans	33.45	6.00e-80	291.00
IUUC-Ang-009669	Aspergillus niger	32.92	9.00e-84	304.00
IUUC-Aor-009914	Aspergillus oryzae	36.01	2.00e-86	313.00
IUUC-Ate-010450	Aspergillus terreus	34.84	2.00e-86	313.00
IUUC-Ame-011183	Astyanax mexicanus	72.11	0.00e+00	825.00
IUUC-Bgr-012111	Blumeria graminis	32.73	2.00e-66	246.00
IUUC-Bta-012583	Bos taurus	95.52	0.00e+00	1066.00
IUUC-Bci-013892	Botrytis cinerea	32.84	7.00e-66	244.00
IUUC-Bdi-014592	Brachypodium distachyon	43.81	4.00e-130	458.00
IUUC-Bol-016401	Brassica oleracea	40.80	2.00e-124	439.00
IUUC-Bra-017506	Brassica rapa	39.21	3.00e-121	428.00
IUUC-Cel-018456	Caenorhabditis elegans	35.90	7.00e-93	334.00
IUUC-Cja-020007	Callithrix jacchus	94.99	0.00e+00	1062.00
IUUC-Cfa-020324	Canis familiaris	95.52	0.00e+00	1063.00
IUUC-Cpo-022248	Cavia porcellus	64.44	1.00e-178	619.00
IUUC-Csa-023149	Chlorocebus sabaeus	96.91	0.00e+00	918.00
IUUC-Cho-024537	Choloepus hoffmanni	84.20	0.00e+00	793.00
IUUC-Cin-025763	Ciona intestinalis	50.00	9.00e-155	540.00
IUUC-Csv-026113	Ciona savignyi	46.21	3.00e-145	508.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	31.72	2.00e-65	243.00
IUUC-Cne-026884	Cryptococcus neoformans	30.51	3.00e-71	263.00
IUUC-Cme-027210	Cyanidioschyzon merolae	26.67	5.00e-19	89.40
IUUC-Dre-028140	Danio rerio	72.40	0.00e+00	841.00
IUUC-Dno-030033	Dasypus novemcinctus	95.34	0.00e+00	936.00
IUUC-Dor-030513	Dipodomys ordii	65.61	5.00e-111	394.00
IUUC-Dse-031536	Dothistroma septosporum	34.97	2.00e-86	313.00
IUUC-Dme-031683	Drosophila melanogaster	43.93	4.00e-126	444.00
IUUC-Ete-032420	Echinops telfairi	82.01	0.00e+00	872.00
IUUC-Eca-033992	Equus caballus	97.09	0.00e+00	906.00
IUUC-Eeu-034713	Erinaceus europaeus	79.53	1.00e-116	413.00
IUUC-Fca-036548	Felis catus	94.40	0.00e+00	1052.00
IUUC-Fal-037600	Ficedula albicollis	80.11	0.00e+00	881.00
IUUC-Fox-038037	Fusarium oxysporum	33.70	3.00e-76	279.00
IUUC-Fso-038387	Fusarium solani	34.77	2.00e-78	286.00
IUUC-Gmo-038562	Gadus morhua	70.86	0.00e+00	820.00
IUUC-Ggr-040005	Gaeumannomyces graminis	34.23	2.00e-73	270.00
IUUC-Gga-041129	Gallus gallus	82.84	0.00e+00	925.00
IUUC-Gac-042558	Gasterosteus aculeatus	71.94	0.00e+00	825.00
IUUC-Gma-043610	Glycine max	41.94	8.00e-122	430.00
IUUC-Ggo-045611	Gorilla gorilla	94.99	0.00e+00	1059.00
IUUC-Hsa-046563	Homo sapiens	95.87	0.00e+00	1063.00
IUUC-Hvu-047790	Hordeum vulgare	39.03	5.00e-78	285.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	94.96	0.00e+00	1062.00
IUUC-Kpa-049309	Komagataella pastoris	35.54	1.00e-82	300.00
IUUC-Lch-050038	Latimeria chalumnae	74.53	0.00e+00	843.00
IUUC-Lpe-051535	Leersia perrieri	41.97	4.00e-113	401.00
IUUC-Loc-051917	Lepisosteus oculatus	68.07	0.00e+00	782.00
IUUC-Lma-053112	Leptosphaeria maculans	36.03	2.00e-89	323.00
IUUC-Laf-053690	Loxodonta africana	94.78	0.00e+00	1060.00
IUUC-Mcc-055117	Macaca mulatta	93.70	0.00e+00	1046.00
IUUC-Meu-056761	Macropus eugenii	75.56	0.00e+00	808.00
IUUC-Mor-057230	Magnaporthe oryzae	33.99	2.00e-78	286.00
IUUC-Mpo-057514	Magnaporthe poae	33.82	3.00e-71	262.00
IUUC-Mtr-058551	Medicago truncatula	41.21	2.00e-118	419.00
IUUC-Mla-059183	Melampsora laricipopulina	36.40	4.00e-97	348.00
IUUC-Mga-060144	Meleagris gallopavo	82.10	0.00e+00	901.00
IUUC-Mvi-060221	Microbotryum violaceum	35.91	7.00e-83	301.00
IUUC-Mmr-061325	Microcebus murinus	92.95	0.00e+00	1038.00
IUUC-Mdo-062532	Monodelphis domestica	89.87	0.00e+00	1004.00
IUUC-Mmu-063956	Mus musculus	94.78	0.00e+00	1057.00
IUUC-Mac-064521	Musa acuminata	41.10	1.00e-122	433.00
IUUC-Mpu-066716	Mustela putorius furo	94.44	0.00e+00	995.00
IUUC-Nfi-068245	Neosartorya fischeri	34.36	2.00e-84	306.00
IUUC-Ncr-068910	Neurospora crassa	35.27	2.00e-78	286.00
IUUC-Nle-070034	Nomascus leucogenys	93.73	0.00e+00	1028.00
IUUC-Opr-070552	Ochotona princeps	84.29	0.00e+00	857.00
IUUC-Ont-071426	Oreochromis niloticus	72.59	0.00e+00	842.00
IUUC-Oan-073389	Ornithorhynchus anatinus	82.96	0.00e+00	767.00
IUUC-Ocu-074911	Oryctolagus cuniculus	94.96	0.00e+00	1065.00
IUUC-Oba-075437	Oryza barthii	43.43	4.00e-120	425.00
IUUC-Obr-076684	Oryza brachyantha	43.45	1.00e-115	410.00
IUUC-Ogl-077170	Oryza glaberrima	43.43	4.00e-120	425.00
IUUC-Ogu-078844	Oryza glumaepatula	44.22	2.00e-113	402.00
IUUC-Oin-079105	Oryza indica	43.43	2.00e-119	422.00
IUUC-Olo-080943	Oryza longistaminata	41.16	6.00e-108	384.00
IUUC-Oni-082891	Oryza nivara	40.76	2.00e-113	402.00
IUUC-Opu-083457	Oryza punctata	43.43	1.00e-119	423.00
IUUC-Oru-084960	Oryza rufipogon	40.95	3.00e-108	385.00
IUUC-Osa-085358	Oryza sativa	43.62	3.00e-120	425.00
IUUC-Ola-086420	Oryzias latipes	70.59	7.00e-166	576.00
IUUC-Olu-087625	Ostreococcus lucimarinus	30.88	5.00e-60	225.00
IUUC-Oga-088810	Otolemur garnettii	94.40	0.00e+00	1054.00
IUUC-Oar-089196	Ovis aries	95.36	0.00e+00	1063.00
IUUC-Ptr-090617	Pan troglodytes	95.71	0.00e+00	1065.00
IUUC-Pan-092761	Papio anubis	95.71	0.00e+00	1068.00
IUUC-Psi-093191	Pelodiscus sinensis	85.52	0.00e+00	953.00
IUUC-Pma-094380	Petromyzon marinus	61.45	0.00e+00	664.00
IUUC-Pno-095084	Phaeosphaeria nodorum	33.27	3.00e-77	283.00
IUUC-Ppa-095875	Physcomitrella patens	40.57	2.00e-120	426.00
IUUC-Pfo-096467	Poecilia formosa	71.62	0.00e+00	826.00
IUUC-Pab-098255	Pongo abelii	94.62	0.00e+00	881.00
IUUC-Pop-099722	Populus trichocarpa	41.51	8.00e-127	447.00
IUUC-Pca-100807	Procavia capensis	77.44	2.00e-116	412.00
IUUC-Ppe-101280	Prunus persica	40.79	1.00e-123	436.00
IUUC-Pva-102333	Pteropus vampyrus	91.84	0.00e+00	1011.00
IUUC-Pgr-103401	Puccinia graminis	32.49	9.00e-80	291.00
IUUC-Ptt-103889	Puccinia triticina	28.50	4.00e-59	222.00
IUUC-Pte-104355	Pyrenophora teres	36.81	2.00e-92	332.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	36.81	2.00e-93	336.00
IUUC-Rno-105810	Rattus norvegicus	94.03	0.00e+00	1048.00
IUUC-Sce-106397	Saccharomyces cerevisiae	26.90	1.00e-37	150.00
IUUC-Sha-106770	Sarcophilus harrisii	87.86	2.00e-149	520.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	33.02	6.00e-80	291.00
IUUC-Spo-108276	Schizosaccharomyces pombe	36.02	4.00e-86	311.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	32.00	2.00e-67	250.00
IUUC-Smo-109296	Selaginella moellendorffii	43.10	9.00e-125	440.00
IUUC-Sit-110157	Setaria italica	45.28	1.00e-136	479.00
IUUC-Sly-111105	Solanum lycopersicum	40.82	2.00e-123	436.00
IUUC-Stu-112469	Solanum tuberosum	41.19	1.00e-125	443.00
IUUC-Sar-113083	Sorex araneus	72.73	0.00e+00	743.00
IUUC-Sbi-113813	Sorghum bicolor	45.28	5.00e-136	477.00
IUUC-Sre-115058	Sporisorium reilianum	38.68	7.00e-85	308.00
IUUC-Tgu-116772	Taeniopygia guttata	80.11	0.00e+00	882.00
IUUC-Tru-118686	Takifugu rubripes	71.46	0.00e+00	832.00
IUUC-Tsy-119111	Tarsius syrichta	86.32	1.00e-143	503.00
IUUC-Tni-120231	Tetraodon nigroviridis	65.98	0.00e+00	744.00
IUUC-Tca-121491	Theobroma cacao	41.17	3.00e-118	418.00
IUUC-Tre-122103	Trichoderma reesei	36.95	1.00e-82	300.00
IUUC-Tvi-122672	Trichoderma virens	37.20	1.00e-76	280.00
IUUC-Tae-125679	Triticum aestivum	43.62	1.00e-129	456.00
IUUC-Tur-126487	Triticum urartu	42.29	2.00e-123	435.00
IUUC-Tme-127097	Tuber melanosporum	38.25	4.00e-95	342.00
IUUC-Ttr-128465	Tursiops truncatus	88.68	0.00e+00	975.00
IUUC-Uma-129645	Ustilago maydis	33.72	6.00e-90	325.00
IUUC-Vda-129989	Verticillium dahliae	31.23	1.00e-57	217.00
IUUC-Vpa-130529	Vicugna pacos	91.09	0.00e+00	1009.00
IUUC-Vvi-131059	Vitis vinifera	41.92	1.00e-123	436.00
IUUC-Xtr-132002	Xenopus tropicalis	78.18	0.00e+00	897.00
IUUC-Xma-133930	Xiphophorus maculatus	72.02	0.00e+00	830.00
IUUC-Yli-134505	Yarrowia lipolytica	35.35	2.00e-86	313.00
IUUC-Zma-135895	Zea mays	45.33	5.00e-135	474.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence