iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033518

Ensembl Protein ID

ENSECAP00000021881.1

UniProt Accession

F6X8X0; F6X8X0_HORSE

Protein Name

Uncharacterized protein

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024186.1	ENSECAT00000026246.1	ENSECAP00000021881.1
ENSECAG00000024186.1	ENSECAT00000026247.1	ENSECAP00000021882.1
ENSECAG00000024186.1	ENSECAT00000026270.1	ENSECAP00000021902.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.00e-29	99.3	1333	1367
UBD/Beta-Prp	5.00e-44	150.8	1437	1652

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1333 GHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQE 1367
           899*****99767*****************99976 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
           + e++++++ ++p+g +++ +++ ++++ wdl+ ++ + +l+gh   v++l++++  +g d +++Gs+d +i+++d+ +g       
   Q: 1437 SGENQINQIALNPTG-TFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQisNGqDLIITGSKDHYIKMFDVTEGALGTVsp 1522
           56789*********9.99**************************************9888*****************9998765467 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
              ++ +h + +  +++++  + l+sGs D+ ++ Wdl++++ll++   +h+d v  l + +  + l+sg + g +klw++ t   v
   Q: 1523 thnFEPPHYDGIEALTIQG--DNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWVCALGVVPGHPVLLSGCRGGILKLWNMDTFVPV 1607
           7889999999999999999..7799**********************999************************************* PP
   S: 216  rtlnghtdnvksvrfspnderlvsgssDgsiriW...dlrsgdllkt 259
            +++gh+++++ + +   ++++ ++++D+++riW   +l+ g++  t
   Q: 1608 GEMKGHDSPINAICVN--STHIFTAADDRTVRIWkarNLQDGQVSDT 1652
           ***********99888..****************9999999988765 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

ISLRIRPQLA KEKIEGCHIC TSVTPGEPQV FLGKDKAFTF DYVFDIDSQQ EQIYAQCIEK 60
LIEGCFEGYN ATVFAYGQTG AGKTYTMGTG FDVNIIEEEQ GIISRAVKHL FKNIEEKKHT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTCTCTCA GAATAAGACC ACAGCTTGCC AAAGAAAAGA TTGAAGGATG CCATATCTGT 60
ACATCTGTCA CACCGGGAGA ACCTCAGGTT TTCCTAGGGA AAGATAAAGC TTTTACTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	96.03	0.00e+00	3062.00
IUUC-Apl-003353	Anas platyrhynchos	84.35	0.00e+00	2647.00
IUUC-Aca-004467	Anolis carolinensis	84.27	0.00e+00	2728.00
IUUC-Ame-011430	Astyanax mexicanus	65.48	0.00e+00	1300.00
IUUC-Bta-013485	Bos taurus	95.97	0.00e+00	2976.00
IUUC-Cel-018402	Caenorhabditis elegans	52.53	3.00e-147	516.00
IUUC-Cja-019385	Callithrix jacchus	92.74	0.00e+00	2948.00
IUUC-Cfa-020986	Canis familiaris	96.88	0.00e+00	3018.00
IUUC-Cpo-022297	Cavia porcellus	92.24	0.00e+00	2882.00
IUUC-Csa-023685	Chlorocebus sabaeus	95.02	0.00e+00	2998.00
IUUC-Cho-024531	Choloepus hoffmanni	91.58	0.00e+00	1072.00
IUUC-Cin-025160	Ciona intestinalis	47.35	4.00e-88	318.00
IUUC-Csv-026158	Ciona savignyi	58.02	2.00e-176	613.00
IUUC-Dre-028532	Danio rerio	67.38	0.00e+00	2102.00
IUUC-Dno-029972	Dasypus novemcinctus	91.36	0.00e+00	2783.00
IUUC-Ete-032872	Echinops telfairi	80.20	0.00e+00	1047.00
IUUC-Fca-036197	Felis catus	96.70	0.00e+00	3017.00
IUUC-Fal-037534	Ficedula albicollis	83.86	0.00e+00	2651.00
IUUC-Gga-040687	Gallus gallus	83.47	0.00e+00	2618.00
IUUC-Gac-041626	Gasterosteus aculeatus	68.27	0.00e+00	2186.00
IUUC-Ggo-044457	Gorilla gorilla	95.91	0.00e+00	2999.00
IUUC-Hsa-046372	Homo sapiens	96.09	0.00e+00	3018.00
IUUC-Lch-049786	Latimeria chalumnae	59.89	0.00e+00	1868.00
IUUC-Loc-052689	Lepisosteus oculatus	74.81	0.00e+00	2378.00
IUUC-Laf-054018	Loxodonta africana	90.20	0.00e+00	2781.00
IUUC-Mcc-055558	Macaca mulatta	96.15	0.00e+00	3026.00
IUUC-Meu-056080	Macropus eugenii	88.93	0.00e+00	997.00
IUUC-Mga-059283	Meleagris gallopavo	83.83	0.00e+00	2586.00
IUUC-Mmr-060773	Microcebus murinus	94.35	0.00e+00	2910.00
IUUC-Mdo-062688	Monodelphis domestica	89.82	0.00e+00	2624.00
IUUC-Mmu-063997	Mus musculus	92.25	0.00e+00	2864.00
IUUC-Mpu-066354	Mustela putorius furo	95.19	0.00e+00	2999.00
IUUC-Mlu-067599	Myotis lucifugus	95.68	0.00e+00	2977.00
IUUC-Nle-069477	Nomascus leucogenys	96.21	0.00e+00	3019.00
IUUC-Opr-070188	Ochotona princeps	79.85	0.00e+00	1772.00
IUUC-Ont-071717	Oreochromis niloticus	58.56	0.00e+00	1030.00
IUUC-Oan-073055	Ornithorhynchus anatinus	88.81	0.00e+00	2653.00
IUUC-Ocu-074302	Oryctolagus cuniculus	91.73	0.00e+00	2926.00
IUUC-Ola-087491	Oryzias latipes	64.28	0.00e+00	1877.00
IUUC-Oga-088799	Otolemur garnettii	94.43	0.00e+00	2689.00
IUUC-Oar-089629	Ovis aries	93.87	0.00e+00	2951.00
IUUC-Pan-092214	Papio anubis	94.59	0.00e+00	2987.00
IUUC-Psi-093757	Pelodiscus sinensis	81.90	0.00e+00	2538.00
IUUC-Pfo-096978	Poecilia formosa	65.86	0.00e+00	1319.00
IUUC-Pab-097984	Pongo abelii	96.21	0.00e+00	2986.00
IUUC-Pca-101061	Procavia capensis	79.04	0.00e+00	1457.00
IUUC-Pva-102306	Pteropus vampyrus	93.81	0.00e+00	2890.00
IUUC-Rno-105354	Rattus norvegicus	91.03	0.00e+00	2818.00
IUUC-Sha-106938	Sarcophilus harrisii	89.07	0.00e+00	1810.00
IUUC-Ssc-115810	Sus scrofa	95.38	0.00e+00	2951.00
IUUC-Tgu-117076	Taeniopygia guttata	81.81	0.00e+00	2523.00
IUUC-Tru-118091	Takifugu rubripes	64.63	0.00e+00	1261.00
IUUC-Tsy-119020	Tarsius syrichta	94.45	0.00e+00	2985.00
IUUC-Tni-120813	Tetraodon nigroviridis	66.61	0.00e+00	2104.00
IUUC-Tbe-127494	Tupaia belangeri	80.79	0.00e+00	1022.00
IUUC-Ttr-128393	Tursiops truncatus	92.83	0.00e+00	2144.00
IUUC-Vpa-130675	Vicugna pacos	83.67	0.00e+00	793.00
IUUC-Xtr-132829	Xenopus tropicalis	79.17	0.00e+00	2540.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence