iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrli 65
           e+  CpI le+ +dPv++ +G+ +  ++I +  +++++  cP+++ +++++++ Pn+ l +l 
   Q: 12   EDVTCPICLEILQDPVTIDCGHNFCLKCINQIGKTSENiLCPLCKCSVSKNTFRPNKLLASLA 74
           6789*************************9965555557******************997765 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCle ++d p++ +CgH f+++C++++     ++s +++CPlC+
   Q: 16   CPICLEILQD-PVTIDCGHNFCLKCINQI----GKTSENILCPLCK 56
           **********.999***************....789*********7 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MADPKMASQL QEDVTCPICL EILQDPVTID CGHNFCLKCI NQIGKTSENI LCPLCKCSVS 60
KNTFRPNKLL ASLAEKIQTM DPADIQQEKE EARCQKHKKK LYYFCEQDGA LLCVVCRDSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTGAGGGA GGGCTTACCG TCTGTTTTCT TCTCTTTAGA ATATTCCCCA TTTAGGTCTG 60
ACTCTTTTCT GTCATTATTG ACTTAACCCC CTCTCTTCCC GTGTCCTCCT CTAATCCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:0032897--P:negative regulation of viral transcription
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:1902186--P:regulation of viral release from host cell

KEGG

rno:294208

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013042	Bos taurus	51.87	7.00e-148	517.00
IUUC-Cho-024490	Choloepus hoffmanni	40.27	7.00e-64	237.00
IUUC-Dno-029706	Dasypus novemcinctus	51.56	3.00e-90	325.00
IUUC-Dor-031004	Dipodomys ordii	46.47	4.00e-84	304.00
IUUC-Ggo-045224	Gorilla gorilla	52.91	8.00e-90	324.00
IUUC-Hsa-046727	Homo sapiens	52.91	2.00e-89	322.00
IUUC-Itr-049020	Ictidomys tridecemlineatus	47.44	2.00e-141	495.00
IUUC-Kpa-049137	Komagataella pastoris	33.33	2.00e-09	57.00
IUUC-Laf-053632	Loxodonta africana	50.39	6.00e-126	444.00
IUUC-Mmu-063149	Mus musculus	82.25	0.00e+00	845.00
IUUC-Nle-069068	Nomascus leucogenys	52.29	2.00e-88	319.00
IUUC-Opr-070792	Ochotona princeps	44.21	4.00e-64	238.00
IUUC-Ocu-074338	Oryctolagus cuniculus	49.85	3.00e-86	311.00
IUUC-Oar-089628	Ovis aries	51.87	5.00e-140	491.00
IUUC-Ptr-090661	Pan troglodytes	52.91	3.00e-90	325.00
IUUC-Pan-091882	Papio anubis	45.92	2.00e-106	379.00
IUUC-Ppa-095342	Physcomitrella patens	29.47	2.00e-09	55.80
IUUC-Pab-098566	Pongo abelii	51.99	3.00e-94	338.00
IUUC-Ssc-115425	Sus scrofa	47.88	3.00e-89	322.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence