iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067328

Ensembl Protein ID

ENSMLUP00000006968.2

UniProt Accession

G1P9Q0; G1P9Q0_MYOLU

Genbank Protein ID

ENSMLUP00000006968

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02008743

Gene Name

GNB4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000007640.2	ENSMLUT00000007634.2	ENSMLUP00000006968.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-37	126.1	224	258
UBD/Beta-Prp	4.10e-50	170.7	46	269

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH +++++++f ++   +++GsdD t++++Dlr +
   Q: 224  GHVSDINAVSFfPNgYAFATGSDDATCRLFDLRAD 258
           8*********99885679**************987 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
            + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   +h++   ++ v+++++ psg++++ G+ d++  +++l+t++    
   Q: 46   RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR 134
           446899*****************************************************************************987776 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
               l gh g  +c ++ + ++ +v++s D+ + lWd++t++  +t+tg h ++v sls++++++ +vsg++d + klwd++ g c ++
   Q: 135  vsrELPGHIGYLSCCRFLD-DSQIVTSSGDTNCALWDIETAQQTTTFTG-HSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQS 221
           6779*************99.67789***********************9.*************************************** PP
   S: 218  lnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           + gh + ++ v f+pn+  +++gs+D + r++dlr ++ l  +++   ++
   Q: 222  FSGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHD--NI 269
           **************************************99988874..44 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MSELEQLRQE AEQLRNQIQD ARKACNDTTL VQITSNMDSV GRIQMRTRRT LRGHLAKIYA 60
MHWGYDSRLL VSASQDGKLI IWDSYTTNKM HAIPLRSSWV MTCAYAPSGN YVACGGLDNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTGAAC TGGAACAGTT GAGGCAGGAA GCCGAACAAC TACGGAATCA GATCCAGGTA 60
AGAGCAATCC TTTTCATTTT CTCAAAAACA TTTTTAACAT TTTTATCTCA TACCAGTAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0007165--P:signal transduction
GO:0021762--P:substantia nigra development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001727	Ailuropoda melanoleuca	98.45	0.00e+00	659.00
IUUC-Apl-003923	Anas platyrhynchos	94.14	1.00e-174	605.00
IUUC-Aca-004754	Anolis carolinensis	94.12	3.00e-175	607.00
IUUC-Bta-013200	Bos taurus	98.45	0.00e+00	658.00
IUUC-Cja-019845	Callithrix jacchus	98.45	0.00e+00	659.00
IUUC-Cfa-020395	Canis familiaris	98.45	0.00e+00	659.00
IUUC-Cpo-021376	Cavia porcellus	97.83	0.00e+00	657.00
IUUC-Csa-023295	Chlorocebus sabaeus	98.76	0.00e+00	660.00
IUUC-Cho-024766	Choloepus hoffmanni	98.15	0.00e+00	662.00
IUUC-Dno-029802	Dasypus novemcinctus	98.36	9.00e-180	622.00
IUUC-Dme-031748	Drosophila melanogaster	81.76	4.00e-173	600.00
IUUC-Ete-032710	Echinops telfairi	95.78	2.00e-178	618.00
IUUC-Eca-033628	Equus caballus	98.14	0.00e+00	657.00
IUUC-Eeu-034978	Erinaceus europaeus	96.34	3.00e-156	543.00
IUUC-Fal-037616	Ficedula albicollis	94.43	6.00e-176	609.00
IUUC-Gmo-039556	Gadus morhua	91.64	3.00e-179	620.00
IUUC-Gga-040249	Gallus gallus	94.43	6.00e-176	609.00
IUUC-Gac-041805	Gasterosteus aculeatus	90.71	3.00e-179	620.00
IUUC-Ggo-044954	Gorilla gorilla	98.45	0.00e+00	659.00
IUUC-Hsa-046105	Homo sapiens	98.76	0.00e+00	660.00
IUUC-Itr-048623	Ictidomys tridecemlineatus	98.76	0.00e+00	657.00
IUUC-Kpa-049192	Komagataella pastoris	38.89	2.00e-62	233.00
IUUC-Mcc-055787	Macaca mulatta	98.76	0.00e+00	660.00
IUUC-Mga-060050	Meleagris gallopavo	94.14	1.00e-174	605.00
IUUC-Mmr-060931	Microcebus murinus	98.76	0.00e+00	660.00
IUUC-Mdo-063055	Monodelphis domestica	94.12	1.00e-175	608.00
IUUC-Mmu-064368	Mus musculus	95.36	0.00e+00	644.00
IUUC-Mpu-066358	Mustela putorius furo	98.45	0.00e+00	659.00
IUUC-Nle-069612	Nomascus leucogenys	98.76	0.00e+00	660.00
IUUC-Ont-071287	Oreochromis niloticus	91.64	3.00e-179	620.00
IUUC-Oan-072913	Ornithorhynchus anatinus	94.74	6.00e-177	612.00
IUUC-Ocu-074126	Oryctolagus cuniculus	98.14	0.00e+00	663.00
IUUC-Ola-087297	Oryzias latipes	91.38	5.00e-180	623.00
IUUC-Oar-089360	Ovis aries	98.45	0.00e+00	659.00
IUUC-Ptr-091437	Pan troglodytes	98.76	0.00e+00	660.00
IUUC-Pan-092195	Papio anubis	98.45	0.00e+00	659.00
IUUC-Psi-093718	Pelodiscus sinensis	94.43	6.00e-176	609.00
IUUC-Pfo-096251	Poecilia formosa	91.33	1.00e-178	619.00
IUUC-Sha-106534	Sarcophilus harrisii	94.12	9.00e-176	608.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	35.48	4.00e-59	221.00
IUUC-Smo-108835	Selaginella moellendorffii	43.58	2.00e-74	272.00
IUUC-Sar-113642	Sorex araneus	98.16	9.00e-160	555.00
IUUC-Tgu-117198	Taeniopygia guttata	94.43	6.00e-176	609.00
IUUC-Tru-118399	Takifugu rubripes	91.02	6.00e-179	619.00
IUUC-Tsy-119354	Tarsius syrichta	95.36	0.00e+00	641.00
IUUC-Ttr-129243	Tursiops truncatus	98.76	0.00e+00	660.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence