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Tag Content
UUCD2 ID IUUC-Pab-098526
UUCD1 version UUC-PoA-00168
Ensembl Protein ID ENSPPYP00000004540.2
UniProt Accession H2NFK5; H2NFK5_PONAB
Genbank Protein ID ENSPPYP00000004540
Protein Name Uncharacterized protein
Genbank Nucleotide ID ABGA01037593
Gene Name CBL
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000003962.2 ENSPPYT00000004718.2 ENSPPYP00000004540.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 2.00e-07 31.5 380 419
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl  w    + +s  + CP Cr
   Q: 380  CKICAENDKD-VKIEPCGHLMCTSCLTSW----Q-ESEGQGCPFCR 419
           99********.******************....5.555555****8 PP
   
Organism Pongo abelii
Protein Sequence
(Fasta)
MAGNVKKSSG AGGGSGSGGS GSGGLIGLMK DAFQPHHHHH HLSPHPPGTV DKKMVEKCWK 60
LMDKVVRLCQ NPKLALKNSP PYILDLLPDT YQHLRTILSR YEGKMETLGE NEYFRVFMEN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-098526|E3,RING|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGCGGCTTT CTGGGAGCTG TGGGCAGGCG AGCTGCTCGA AACCGGTGGC CCGGGGGTCG 60
TCGCTGCCCA GTCCGGCCGC GGCCGGCCGC TTCCCCGAGC TTACCAGTAA GCCGGTCCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-098526|E3,RING|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR009060--UBA-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3
PF00627--UBA
SMART

SM00184--RING
SM00165--UBA
Gene Ontology

GO:0005829--C:cytosol
GO:0016600--C:flotillin complex
GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0043066--P:negative regulation of apoptotic process
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0048260--P:positive regulation of receptor-mediated endocytosis
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002357 Ailuropoda melanoleuca 91.42 0.00e+00 1483.00
IUUC-Apl-004041 Anas platyrhynchos 84.71 0.00e+00 1376.00
IUUC-Aca-004899 Anolis carolinensis 81.18 0.00e+00 1258.00
IUUC-Ame-010746 Astyanax mexicanus 60.11 0.00e+00 627.00
IUUC-Bta-012759 Bos taurus 91.57 0.00e+00 1526.00
IUUC-Cja-019207 Callithrix jacchus 97.25 0.00e+00 1628.00
IUUC-Cfa-020897 Canis familiaris 93.24 0.00e+00 1531.00
IUUC-Cpo-021453 Cavia porcellus 91.31 0.00e+00 1516.00
IUUC-Csa-023136 Chlorocebus sabaeus 98.24 0.00e+00 1625.00
IUUC-Cho-024282 Choloepus hoffmanni 86.31 0.00e+00 1269.00
IUUC-Cin-025574 Ciona intestinalis 71.54 1.00e-177 615.00
IUUC-Csv-025938 Ciona savignyi 69.87 7.00e-173 599.00
IUUC-Dre-027644 Danio rerio 68.88 0.00e+00 1040.00
IUUC-Dno-030025 Dasypus novemcinctus 93.20 0.00e+00 1492.00
IUUC-Dme-032213 Drosophila melanogaster 74.81 0.00e+00 644.00
IUUC-Ete-033118 Echinops telfairi 80.23 0.00e+00 817.00
IUUC-Eca-033900 Equus caballus 94.37 0.00e+00 1514.00
IUUC-Eeu-035142 Erinaceus europaeus 86.08 0.00e+00 961.00
IUUC-Fca-035455 Felis catus 91.72 0.00e+00 1513.00
IUUC-Fal-037182 Ficedula albicollis 95.01 0.00e+00 902.00
IUUC-Gmo-038698 Gadus morhua 87.30 0.00e+00 870.00
IUUC-Gga-040438 Gallus gallus 83.74 0.00e+00 1408.00
IUUC-Gac-042166 Gasterosteus aculeatus 76.49 0.00e+00 888.00
IUUC-Ggo-045618 Gorilla gorilla 98.90 0.00e+00 1644.00
IUUC-Hsa-046177 Homo sapiens 99.01 0.00e+00 1634.00
IUUC-Itr-048795 Ictidomys tridecemlineatus 96.29 0.00e+00 1010.00
IUUC-Lch-050095 Latimeria chalumnae 74.56 0.00e+00 1169.00
IUUC-Loc-052570 Lepisosteus oculatus 71.65 0.00e+00 1122.00
IUUC-Laf-054008 Loxodonta africana 91.46 0.00e+00 1538.00
IUUC-Mcc-054676 Macaca mulatta 98.13 0.00e+00 1622.00
IUUC-Mga-059239 Meleagris gallopavo 83.37 0.00e+00 1410.00
IUUC-Mmr-060907 Microcebus murinus 93.08 0.00e+00 1537.00
IUUC-Mdo-062595 Monodelphis domestica 88.19 0.00e+00 1414.00
IUUC-Mmu-063725 Mus musculus 91.69 0.00e+00 1581.00
IUUC-Mpu-066771 Mustela putorius furo 91.80 0.00e+00 1532.00
IUUC-Mlu-067206 Myotis lucifugus 76.35 0.00e+00 1087.00
IUUC-Nle-069285 Nomascus leucogenys 95.70 0.00e+00 1528.00
IUUC-Opr-071026 Ochotona princeps 92.76 0.00e+00 1496.00
IUUC-Ont-071954 Oreochromis niloticus 70.56 0.00e+00 1041.00
IUUC-Ocu-074657 Oryctolagus cuniculus 92.71 0.00e+00 1462.00
IUUC-Ola-087165 Oryzias latipes 66.91 0.00e+00 1059.00
IUUC-Oga-088198 Otolemur garnettii 83.95 0.00e+00 1340.00
IUUC-Oar-090258 Ovis aries 91.68 0.00e+00 1463.00
IUUC-Ptr-090710 Pan troglodytes 99.01 0.00e+00 1634.00
IUUC-Pan-092785 Papio anubis 98.13 0.00e+00 1623.00
IUUC-Pfo-096990 Poecilia formosa 90.16 0.00e+00 818.00
IUUC-Pca-100984 Procavia capensis 78.97 2.00e-170 592.00
IUUC-Pva-102352 Pteropus vampyrus 96.86 0.00e+00 897.00
IUUC-Rno-105876 Rattus norvegicus 90.07 0.00e+00 1547.00
IUUC-Sha-107588 Sarcophilus harrisii 86.10 0.00e+00 1224.00
IUUC-Sar-112959 Sorex araneus 88.48 0.00e+00 1426.00
IUUC-Ssc-115261 Sus scrofa 93.01 0.00e+00 1542.00
IUUC-Tgu-116580 Taeniopygia guttata 81.66 0.00e+00 1313.00
IUUC-Tru-118731 Takifugu rubripes 68.34 0.00e+00 1035.00
IUUC-Tsy-118982 Tarsius syrichta 87.86 0.00e+00 1064.00
IUUC-Tni-120725 Tetraodon nigroviridis 68.71 0.00e+00 1032.00
IUUC-Tbe-128018 Tupaia belangeri 95.43 0.00e+00 1161.00
IUUC-Ttr-128927 Tursiops truncatus 93.78 0.00e+00 1586.00
IUUC-Vpa-130369 Vicugna pacos 93.71 0.00e+00 1447.00
IUUC-Xtr-132474 Xenopus tropicalis 73.83 0.00e+00 1145.00
Created Date 25-Jun-2017

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