iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045392

Ensembl Protein ID

ENSGGOP00000023666.1

UniProt Accession

G3S6F9; G3S6F9_GORGO

Protein Name

Uncharacterized protein

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000001197.2	ENSGGOT00000000158.2	ENSGGOP00000023666.1
ENSGGOG00000001197.2	ENSGGOT00000001206.2	ENSGGOP00000001182.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-31	106.3	1552	1586
UBD/Beta-Prp	7.30e-52	176.8	1419	1622

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++laf ++ ++l+s+++ g+ikvW+++ ++
   Q: 1552 HKDWVCALAFiPGrPMLLSACRAGVIKVWNVDNFT 1586
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqclee... 131
            e +++++ +s++g +++ +++ +++++w+ls +++v +l+gh   v++l++ +   + d +v+Gs+d ++++++l  g+c+     
   Q: 1419 GEHQINQIALSSSG-TMLYAASGNAVRIWELSRFQPVGKLTGHIGPVMCLTVTQtasQHDLVVTGSKDHYVKMFEL--GECVTGtig 1502
           5667999******9.99999********************************9998556***************65..667765779 PP
   S: 132  ....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
               ++ +h + + c+++++  ++l+sGs D+ ++ Wdl +++l+++   +h+d v  l+f + ++ l+s+ + g +k+w++ + + 
   Q: 1503 pthnFEPPHYDGIECLAIQG--DILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWNVDNFTP 1587
           9999999***********99..9*************************999************************************ PP
   S: 215  vrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           + + +gh+++++ + +    +++ ++ssD  +++W++
   Q: 1588 IGEIKGHDSPINAICTN--AKHIFTASSDCRVKLWNY 1622
           ************77777..****************96 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAGQGDCCVK VAVRIRPQLS KEKIEGCHIC TSVTPGEPQV LLGKDKAFTY DFVFDLDTWQ 60
EQIYSTCVSK LIEGCFEGYN ATVLAYGQTG AGKTYTMGTG FDMATSEEEQ GIIPRAIAHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGGTGGC TGCCGGGTGG GAGGTGTGTG CGCGTGTGCC GCGCCGTAGG GAGCGGCGGG 60
TCGCGCTGCC GGCTGTCAGC TAGCTCCGCG CCGCCGCCCG ATGGCGCGAG GAGGCGCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	96.37	0.00e+00	2823.00
IUUC-Apl-003204	Anas platyrhynchos	76.23	0.00e+00	1579.00
IUUC-Aca-004506	Anolis carolinensis	82.04	0.00e+00	1632.00
IUUC-Ame-011515	Astyanax mexicanus	75.51	0.00e+00	1457.00
IUUC-Bta-013185	Bos taurus	77.11	0.00e+00	2179.00
IUUC-Cja-018844	Callithrix jacchus	94.84	0.00e+00	2866.00
IUUC-Cfa-021187	Canis familiaris	97.45	0.00e+00	2889.00
IUUC-Cpo-022444	Cavia porcellus	94.23	0.00e+00	2842.00
IUUC-Csa-023852	Chlorocebus sabaeus	98.97	0.00e+00	2941.00
IUUC-Dre-027839	Danio rerio	75.25	0.00e+00	1443.00
IUUC-Dno-030058	Dasypus novemcinctus	92.64	0.00e+00	2763.00
IUUC-Dor-030673	Dipodomys ordii	92.21	0.00e+00	2679.00
IUUC-Ete-032705	Echinops telfairi	83.06	0.00e+00	902.00
IUUC-Eca-033885	Equus caballus	95.83	0.00e+00	2805.00
IUUC-Eeu-035338	Erinaceus europaeus	82.64	0.00e+00	2201.00
IUUC-Fca-035388	Felis catus	97.61	0.00e+00	2702.00
IUUC-Fal-037044	Ficedula albicollis	87.14	0.00e+00	2693.00
IUUC-Gmo-039034	Gadus morhua	68.06	0.00e+00	1261.00
IUUC-Gac-041328	Gasterosteus aculeatus	72.45	0.00e+00	2272.00
IUUC-Hsa-046713	Homo sapiens	99.27	0.00e+00	2950.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	97.25	0.00e+00	1688.00
IUUC-Loc-052703	Lepisosteus oculatus	79.30	0.00e+00	2494.00
IUUC-Laf-054193	Loxodonta africana	86.75	0.00e+00	2491.00
IUUC-Mcc-055484	Macaca mulatta	97.50	0.00e+00	2902.00
IUUC-Meu-056278	Macropus eugenii	82.96	0.00e+00	1197.00
IUUC-Mga-059816	Meleagris gallopavo	84.13	0.00e+00	2575.00
IUUC-Mmr-061071	Microcebus murinus	93.48	0.00e+00	2784.00
IUUC-Mdo-062845	Monodelphis domestica	90.89	0.00e+00	2785.00
IUUC-Mmu-063967	Mus musculus	95.75	0.00e+00	2823.00
IUUC-Mpu-066448	Mustela putorius furo	95.87	0.00e+00	2873.00
IUUC-Nle-070037	Nomascus leucogenys	97.10	0.00e+00	2246.00
IUUC-Opr-070325	Ochotona princeps	91.95	0.00e+00	2660.00
IUUC-Ont-071851	Oreochromis niloticus	72.83	0.00e+00	2303.00
IUUC-Oan-073615	Ornithorhynchus anatinus	88.60	0.00e+00	2543.00
IUUC-Ocu-073855	Oryctolagus cuniculus	96.30	0.00e+00	2842.00
IUUC-Ola-086703	Oryzias latipes	71.67	0.00e+00	2274.00
IUUC-Oga-088171	Otolemur garnettii	94.90	0.00e+00	2815.00
IUUC-Oar-089693	Ovis aries	78.13	0.00e+00	1232.00
IUUC-Ptr-090535	Pan troglodytes	97.83	0.00e+00	1845.00
IUUC-Pan-091917	Papio anubis	98.84	0.00e+00	2710.00
IUUC-Psi-093752	Pelodiscus sinensis	77.96	0.00e+00	1400.00
IUUC-Pfo-096827	Poecilia formosa	69.94	0.00e+00	1358.00
IUUC-Pab-098441	Pongo abelii	99.15	0.00e+00	2959.00
IUUC-Pca-100781	Procavia capensis	95.38	0.00e+00	905.00
IUUC-Pva-103099	Pteropus vampyrus	91.16	0.00e+00	1352.00
IUUC-Rno-105872	Rattus norvegicus	95.57	0.00e+00	2866.00
IUUC-Sha-107097	Sarcophilus harrisii	89.31	0.00e+00	2650.00
IUUC-Ssc-115638	Sus scrofa	94.52	0.00e+00	2462.00
IUUC-Tgu-116504	Taeniopygia guttata	87.24	0.00e+00	1696.00
IUUC-Tru-118242	Takifugu rubripes	73.31	0.00e+00	1480.00
IUUC-Ttr-128824	Tursiops truncatus	89.70	0.00e+00	2258.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence